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Many imaging techniques for biological systems -- like fixation of cells coupled with fluorescence microscopy -- provide sharp spatial resolution in reporting locations of individuals at a single moment in time but also destroy the dynamics…

Subcellular Processes · Quantitative Biology 2024-05-15 Christopher E. Miles , Scott A. McKinley , Fangyuan Ding , Richard B. Lehoucq

Cell extrusion is an essential mechanism for controlling cell density in epithelial tissues. Another essential element of epithelia is curvature, which is required to achieve complex shapes, like in the lung or intestine. Here we introduce…

We consider identification, inference and validation of linear panel data models when both factors and factor loadings are accounted for by a nonparametric function. This general specification encompasses rather popular models such as the…

Econometrics · Economics 2025-06-13 Juan M. Rodriguez-Poo , Alexandra Soberon , Stefan Sperlich

A continuum model of epithelial tissue mechanics was formulated using cellular-level mechanical ingredients and cell morphogenetic processes, including cellular shape changes and cellular rearrangements. This model can include finite…

Tissues and Organs · Quantitative Biology 2017-09-06 Shuji Ishihara , Philippe Marcq , Kaoru Sugimura

Adapting pre-trained foundation models for various downstream tasks has been prevalent in artificial intelligence. Due to the vast number of tasks and high costs, adjusting all parameters becomes unfeasible. To mitigate this, several…

Computer Vision and Pattern Recognition · Computer Science 2025-02-07 Chongjie Si , Xuehui Wang , Xue Yang , Zhengqin Xu , Qingyun Li , Jifeng Dai , Yu Qiao , Xiaokang Yang , Wei Shen

The deformation of cellular membranes regulates trafficking processes, such as exocytosis and endocytosis. Classically, the Helfrich continuum model is used to characterize the forces and mechanical parameters that cells tune to accomplish…

Quantitative Methods · Quantitative Biology 2022-06-14 Sage Malingen , Padmini Rangamani

In this work I have studied the effect of disorder and system size in fiber bundle model with a certain range of stress redistribution. The strength of the bundle as well as the failure abruptness is observed with varying disorder, stress…

Statistical Mechanics · Physics 2017-11-02 Subhadeep Roy

As two-dimensional fluid shells, lipid bilayer membranes resist bending and stretching but are unable to sustain shear stresses. This property gives membranes the ability to adopt dramatic shape changes. In this paper, a finite element…

Biological Physics · Physics 2009-11-13 Lin Ma , William S. Klug

Topological defects are ubiquitous on surfaces with orientational order fields. Here, we study equilibrium states generated by the feedback between geometry and nematic order on fluid membranes with an integer topological defect. When the…

Soft Condensed Matter · Physics 2024-11-14 D. J. G. Pearce , C. Thibault , Q. Chaboche , C. Blanch-Mercader

In global supersymmetric Wess-Zumino models with minimal K\"ahler potentials, F-type supersymmetry breaking always yields instability or continuous degeneracy of non-supersymmetric vacua. As a generalization of the original O'Raifeartaigh's…

High Energy Physics - Theory · Physics 2011-05-17 Zheng Sun

Owing to additive manufacturing techniques, a structure at millimeter length scale (macroscale) can be produced by using a lattice substructure at micrometer length scale (microscale). Such a system is called a metamaterial at the…

Computational Engineering, Finance, and Science · Computer Science 2019-11-25 H. Yang , B. E. Abali , W. H. Müller , D. Timofeev

Computational models in cardiac electrophysiology are notorious for long runtimes, restricting the numbers of nodes and mesh elements in the numerical discretisations used for their solution. This makes it particularly challenging to…

Recent precision cosmological parameter constraints imply that the spatial curvature of the Universe is essentially dynamically negligible - but only if relatively strong assumptions are made about the equation of state of dark energy (DE).…

Cosmology and Nongalactic Astrophysics · Physics 2018-05-02 Amadeus Witzemann , Philip Bull , Chris Clarkson , Mario G. Santos , Marta Spinelli , Amanda Weltman

Many classical geometric inequalities on functionals of convex bodies depend on the dimension of the ambient space. We show that this dimension dependence may often be replaced (totally or partially) by different symmetry measures of the…

Metric Geometry · Mathematics 2014-12-11 René Brandenberg , Stefan König

We examine the dark energy and matter densities allowed by precision measurements of distances out to various redshifts, in the presence of spatial curvature and (near) arbitrary behavior of the dark energy equation of state. Degeneracies…

Cosmology and Nongalactic Astrophysics · Physics 2011-09-22 Arman Shafieloo , Eric V. Linder

Heterogeneity is classified in five categories---topologic, geometric, kinematic, static, and constitutive---and the first four categories are investigated in a numerical DEM simulation of biaxial compression. The simulation experiments…

Soft Condensed Matter · Physics 2019-01-23 Matthew R. Kuhn

We study how the properties of a Lagrangian density for a single real scalar field in flat spacetime change with inclusion of an overall factor depending only on the field. The focus of the paper is to obtain analytical results. So, we show…

High Energy Physics - Theory · Physics 2017-11-20 L. Losano , M. A. Marques , R. Menezes

In this paper we construct coherent states for the two-dimensional Morse potential. We find the dependence of the spectrum on the physical parameters and use this to understand the emergence of accidental degeneracies. It is observed that,…

Quantum Physics · Physics 2021-07-29 James Moran

We study the continuum limit of discrete, nonconvex energy functionals defined on crystal lattices in dimensions $d\geq 2$. Since we are interested in energy functionals with random (stationary and ergodic) pair interactions, our problem…

Analysis of PDEs · Mathematics 2018-07-26 Stefan Neukamm , Mathias Schaffner , Anja Schlomerkemper

Recently the materials possessing structure of molecular and supramolecular matrix are more and more actively studied. They are relative to many polymeric materials of a technological origin, such as rubber, and living biological tissues.…

Adaptation and Self-Organizing Systems · Physics 2013-06-27 A. A. Bedulina , A. V. Kobelev