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Coordinated collaboration is essential to realize the added value of and infrastructure requirements for global image data sharing in the life sciences. In this White Paper, we take a first step at presenting some of the most common use…

Existing image segmentation networks mainly leverage large-scale labeled datasets to attain high accuracy. However, labeling medical images is very expensive since it requires sophisticated expert knowledge. Thus, it is more desirable to…

Image and Video Processing · Electrical Eng. & Systems 2021-02-04 Yuhang Ding , Xin Yu , Yi Yang

Background:The electrocardiogram (ECG) is one of the most commonly used diagnostic tools in medicine and healthcare. Deep learning methods have achieved promising results on predictive healthcare tasks using ECG signals. Objective:This…

Signal Processing · Electrical Eng. & Systems 2020-05-04 Shenda Hong , Yuxi Zhou , Junyuan Shang , Cao Xiao , Jimeng Sun

Over the last decade, electron microscopy has improved up to a point that generating high quality gigavoxel sized datasets only requires a few hours. Automated image analysis, particularly image segmentation, however, has not evolved at the…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Joris Roels , Yvan Saeys

List-mode data is increasingly being uesd in SPECT and PET imaging, among other imaging modalities. However, there are still many imaging designs that effectively bin list-mode data before image reconstruction or other estimation tasks are…

Information Theory · Computer Science 2020-03-18 Eric Clarkson

Data is a cornerstone of empirical software engineering (ESE) research and practice. Data underpin numerous process and project management activities, including the estimation of development effort and the prediction of the likely location…

Software Engineering · Computer Science 2020-12-22 Michael F. Bosu , Stephen G. MacDonell

The next-generation radio astronomy instruments are providing a massive increase in sensitivity and coverage, through increased stations in the array and frequency span. Two primary problems encountered when processing the resultant…

Instrumentation and Methods for Astrophysics · Physics 2025-07-30 Richard Dodson , Alex Williamson , Qian Gong , Pascal Elahi , Andreas Wicenec , Maria J. Rioja , Jieyang Chen , Norbert Podhorszki , Scott Klasky , Martin Meyer

Light microscopy allows observing cellular features and objects with sub-micrometer resolution. As such, light microscopy has been playing a fundamental role in the life sciences for more than a hundred years. Fueled by the availability of…

Other Quantitative Biology · Quantitative Biology 2021-10-28 Johannes Hohlbein , Benedict Diederich , Barbora Marsikova , Emmanuel G. Reynaud , Seamus Holden , Wiebke Jahr , Robert Haase , Kirti Prakash

Fluorescence microscopy, widely used in the study of living cells, tissues, and organisms, often faces the challenge of photodamage. This is primarily caused by the interaction between light and biochemical components during the imaging…

Quantitative Methods · Quantitative Biology 2024-04-01 Estibaliz Gómez-de-Mariscal , Mario Del Rosario , Joanna W Pylvänäinen , Guillaume Jacquemet , Ricardo Henriques

Dealing with missing modalities in Magnetic Resonance Imaging (MRI) and overcoming their negative repercussions is considered a hurdle in biomedical imaging. The combination of a specified set of modalities, which is selected depending on…

Image and Video Processing · Electrical Eng. & Systems 2022-03-15 Reza Azad , Nika Khosravi , Mohammad Dehghanmanshadi , Julien Cohen-Adad , Dorit Merhof

Identification of charged particles in a multilayer detector by the energy loss technique may also be achieved by the use of a neural network. The performance of the network becomes worse when a large fraction of information is missing, for…

Methodology · Statistics 2020-04-14 S. Riggi , D. Riggi , F. Riggi

Information extracted from electrohysterography recordings could potentially prove to be an interesting additional source of information to estimate the risk on preterm birth. Recently, a large number of studies have reported near-perfect…

Previous studies have shown that many users do not use effective data deletion techniques upon sale or surrender of storage devices. A logical assumption is that many users are still confused concerning proper sanitization techniques of…

Cryptography and Security · Computer Science 2015-12-31 Sarah Diesburg , C. Adam Feldhaus , Mojtaba Al Fardan , Jonathan Schlicht , Nigel Ploof

The Scanning electron microscope (SEM) and Electron-Dispersive Spectroscope (EDS) are two highly effective instruments in the field of nanoscience and nanotechnology. The quality of these instruments is determined by various factors, with…

Applied Physics · Physics 2023-10-24 Hamidreza Moradi , Fatemeh Mehradnia

Due to numerous hardware shortcomings, medical image acquisition devices are susceptible to producing low-quality (i.e., low contrast, inappropriate brightness, noisy, etc.) images. Regrettably, perceptually degraded images directly impact…

Image and Video Processing · Electrical Eng. & Systems 2025-03-12 S M A Sharif , Rizwan Ali Naqvi , Mithun Biswas , Woong-Kee Loh

In present technological era, healthcare providers generate huge amount of clinical data on daily basis. Generated clinical data is stored digitally in the form of Electronic Health Records (EHR) as a central data repository of hospitals.…

Computers and Society · Computer Science 2020-08-07 Shahid Munir Shah , Rizwan Ahmed Khan

The complexity of human biology and its intricate systems holds immense potential for advancing human health, disease treatment, and scientific discovery. However, traditional manual methods for studying biological interactions are often…

Other Quantitative Biology · Quantitative Biology 2025-01-24 Himanshu Buckchash , Gyanendra Kumar Verma , Dilip K. Prasad

Cryo-electron microscopy (cryo-EM) studies using single particle reconstruction are extensively used to reveal structural information on macromolecular complexes. Aiming at the highest achievable resolution, state of the art electron…

Scanning Electron Microscopy (SEM) is critical in nanotechnology, materials science, and biological imaging due to its high spatial resolution and depth of focus. Signal-to-noise ratio (SNR) is an essential parameter in SEM because it…

Machine Learning · Computer Science 2025-10-10 K. S. Sim , I. Bukhori , D. C. Y. Ong , K. B. Gan

The high beam current and sub-angstrom resolution of aberration-corrected scanning transmission electron microscopes has enabled electron energy loss spectroscopic (EELS) mapping with atomic resolution. These spectral maps are often…

Materials Science · Physics 2023-07-19 Paul Cueva , Robert Hovden , Julia A. Mundy , Huolin L. Xin , David A. Muller