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Molecular dynamics (MD) is a powerful technique for studying microscopic phenomena, but its computational cost has driven significant interest in the development of deep learning-based surrogate models. We introduce generative modeling of…

Biomolecules · Quantitative Biology 2024-09-27 Bowen Jing , Hannes Stärk , Tommi Jaakkola , Bonnie Berger

We expand iterative numerically-exact influence functional path-integral tools and present a method capable of following the nonequilibrium time evolution of subsystems coupled to multiple bosonic and fermionic reservoirs simultaneously.…

Mesoscale and Nanoscale Physics · Physics 2015-06-15 Lena Simine , Dvira Segal

Human brain processes sensory information in real-time with extraordinary efficiency compared to the possibilities of current artificial computing systems. It operates as a complex nonlinear system, composed of interacting dynamic units -…

Emerging Technologies · Computer Science 2025-04-21 Manuel Escudero , Sabina Spiga , Stefano Brivio

Active systems across scales, ranging from molecular machines to human crowds, are usually modeled as assemblies of self-propelled particles driven by internally generated forces. However, these models often assume memoryless dynamics and…

Statistical Mechanics · Physics 2025-12-10 Marc Besse , Raphaël Voituriez

Molecular-scale computation is crucial for smart materials and nanoscale devices, yet creating single-molecule systems capable of complex computations remains challenging. We present a theoretical framework for a single-molecule computer…

Statistical Mechanics · Physics 2024-10-01 Zhongmin Zhang , Zhiyue Lu

Molecular dynamics simulations are indispensable for exploring the behavior of atoms and molecules. Grounded in quantum mechanical principles, quantum molecular dynamics provides high predictive power but its computational cost is dominated…

Chemical Physics · Physics 2025-09-10 Siu Wun Cheung , Youngsoo Choi , Jean-Luc Fattebert , Daniel Osei-Kuffuor

The initial stages of the evolution of an open quantum system encode the key information of its underlying dynamical correlations, which in turn can predict the trajectory at later stages. We propose a general approach based on…

Quantum Physics · Physics 2015-10-20 Javier Cerrillo , Jianshu Cao

Molecular dynamics simulations yield large amounts of trajectory data. For their durable storage and accessibility an efficient compression algorithm is paramount. State of the art domain-specific algorithms combine quantization, Huffman…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-01-13 Jan Huwald , Stephan Richter , Peter Dittrich

The prediction of complex dynamics remains an open problem across many domains of physics, where nonlinearities and multiscale interactions severely limit the reliability of conventional forecasting methods. Quantum reservoir computing…

Biological systems are promising substrates for computation because they naturally process environmental information through complex internal dynamics. In this study, we investigate whether bacterial metabolic models can act as physical…

Emerging Technologies · Computer Science 2026-04-23 Laura Alonso Bartolomé , Jean-Loup Faulon , Xavier Hinaut

This paper presents a novel methodology for the direct numerical modeling and simulation of turbulent flows. The kinetic model equation is firstly extended to turbulent flow with the account of coupled evolution of kinetic, thermal, and…

Computational Physics · Physics 2025-03-11 Xiaojian Yang , Kun Xu

Advances in artificial intelligence are driven by technologies inspired by the brain, but these technologies are orders of magnitude less powerful and energy efficient than biological systems. Inspired by the nonlinear dynamics of neural…

A system of degenerate drift-diffusion equations for the electron, hole, and oxygen vacancy densities, coupled to the Poisson equation for the electric potential, is analyzed in a three-dimensional bounded domain with mixed…

Analysis of PDEs · Mathematics 2023-11-29 Ansgar Jüngel , Martin Vetter

The Hopfield model provides a mathematically idealized yet insightful framework for understanding the mechanisms of memory storage and retrieval in the human brain. This model has inspired four decades of extensive research on learning and…

Neurons and Cognition · Quantitative Biology 2025-05-14 Simone Betteti , Giacomo Baggio , Francesco Bullo , Sandro Zampieri

We introduce a numerical tensor-network method to compute the statistics of the charge transferred across an interface partitioning an interacting one-dimensional many-body lattice system with $U(1)$ symmetry. Our approach is based on a…

Quantum Physics · Physics 2026-04-01 Hari Kumar Yadalam , Mark T. Mitchison

Memristive reservoirs draw inspiration from a novel class of neuromorphic hardware known as nanowire networks. These systems display emergent brain-like dynamics, with optimal performance demonstrated at dynamical phase transitions. In…

Disordered Systems and Neural Networks · Physics 2023-06-23 Ruomin Zhu , Jason K. Eshraghian , Zdenka Kuncic

We discuss nuclear dynamics at molecule-metal interfaces including non-equilibrium molecular junctions. Starting from the many-body states (pseudoparticle) formulation of the molecule-metal system in the molecular vibronic basis, we…

Mesoscale and Nanoscale Physics · Physics 2015-11-30 Michael Galperin , Abraham Nitzan

Quantum reservoir computing (QRC) leverages the high-dimensional, nonlinear dynamics inherent in quantum many-body systems for extracting spatiotemporal patterns in sequential and time-series data with minimal training overhead. Although…

Quantum Physics · Physics 2025-10-22 Shehbaz Tariq , Muhammad Talha , Symeon Chatzinotas , Hyundong Shin

Using methods of kinetic theory and liquid state theory we propose a description of the non-equilibrium behavior of molecular fluids which takes into account their microscopic structure and thermodynamic properties. The present work…

Statistical Mechanics · Physics 2009-02-24 Umberto Marini Bettolo Marconi , Simone Melchionna

Quantum reservoir computing has emerged as a promising paradigm for harnessing quantum systems to process temporal data efficiently by bypassing the costly training of gradient-based learning methods. Here, we demonstrate the capability of…

Quantum Physics · Physics 2026-03-20 Qingyu Li , Chiranjib Mukhopadhyay , Ludovico Minati , Abolfazl Bayat