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Multiple sclerosis (MS) lesions occupy a small fraction of the brain volume, and are heterogeneous with regards to shape, size and locations, which poses a great challenge for training deep learning based segmentation models. We proposed a…
We propose two novel loss functions, Multiplicative Loss and Confidence-Adaptive Multiplicative Loss, for semantic segmentation in medical and cellular images. Although Cross Entropy and Dice Loss are widely used, their additive combination…
Widely used loss functions for CNN segmentation, e.g., Dice or cross-entropy, are based on integrals over the segmentation regions. Unfortunately, for highly unbalanced segmentations, such regional summations have values that differ by…
Within medical imaging segmentation, the Dice coefficient and Hausdorff-based metrics are standard measures of success for deep learning models. However, modern loss functions for medical image segmentation often only consider the Dice…
Simultaneous segmentation of multiple organs from different medical imaging modalities is a crucial task as it can be utilized for computer-aided diagnosis, computer-assisted surgery, and therapy planning. Thanks to the recent advances in…
The segmentation of skin lesions is a crucial task in clinical decision support systems for the computer aided diagnosis of skin lesions. Although deep learning-based approaches have improved segmentation performance, these models are often…
Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…
The accuracy of deep learning methods for two foundational tasks in medical image analysis -- detection and segmentation -- can suffer from class imbalance. We propose a `switching loss' function that adaptively shifts the emphasis between…
New lesion segmentation is essential to estimate the disease progression and therapeutic effects during multiple sclerosis (MS) clinical treatments. However, the expensive data acquisition and expert annotation restrict the feasibility of…
Deep-learning has proved in recent years to be a powerful tool for image analysis and is now widely used to segment both 2D and 3D medical images. Deep-learning segmentation frameworks rely not only on the choice of network architecture but…
Loss functions are error metrics that quantify the difference between a prediction and its corresponding ground truth. Fundamentally, they define a functional landscape for traversal by gradient descent. Although numerous loss functions…
Multi-task learning (MTL) can improve performance on a task by sharing representations with one or more related auxiliary-tasks. Usually, MTL-networks are trained on a composite loss function formed by a constant weighted combination of the…
Automatic segmentation methods are an important advancement in medical image analysis. Machine learning techniques, and deep neural networks in particular, are the state-of-the-art for most medical image segmentation tasks. Issues with…
We study the impact of different loss functions on lesion segmentation from medical images. Although the Cross-Entropy (CE) loss is the most popular option when dealing with natural images, for biomedical image segmentation the soft Dice…
Accurate segmentation of Multiple Sclerosis (MS) lesions in longitudinal MRI scans is crucial for monitoring disease progression and treatment efficacy. Although changes across time are taken into account when assessing images in clinical…
This paper presents a comprehensive review of loss functions and performance metrics in deep learning, highlighting key developments and practical insights across diverse application areas. We begin by outlining fundamental considerations…
Pathological morphology diagnosis is the standard diagnosis method of hydatidiform mole. As a disease with malignant potential, the hydatidiform mole section of hydrops lesions is an important basis for diagnosis. Due to incomplete lesion…
Segmentation of Hypoxic-Ischemic Encephalopathy (HIE) lesions in neonatal MRI is a crucial but challenging task due to diffuse multifocal lesions with varying volumes and the limited availability of annotated HIE lesion datasets. Using the…
Image segmentation is critically important in almost all medical image analysis for automatic interpretations and processing. However, it is often challenging to perform image segmentation due to data imbalance between intra- and…
Loss functions drive the optimization of machine learning algorithms. The choice of a loss function can have a significant impact on the training of a model, and how the model learns the data. Binary classification is one of the major…