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Topology optimization (TO) can be viewed as seeking an optimal solution in the design space of a given TO problem. For weakly non-linear TO problems, e.g., compliance minimization, sensitivity-based methods typically converge well, whereas…

Optimization and Control · Mathematics 2026-03-25 Ziliang Wang , Jiahua Wu , Jun Yang , Shintaro Yamasaki

13C-based metabolic flux analysis (13C-MFA) is a cornerstone of quantitative systems biology, yet its increasing data complexity and methodological diversity place high demands on simulation software. We introduce 13CFLUX(v3), a…

Quantitative Methods · Quantitative Biology 2025-09-30 Anton Stratmann , Martin Beyß , Johann F. Jadebeck , Wolfgang Wiechert , Katharina Nöh

Despite the remarkable progress of large language models (LLMs), the capabilities of standalone LLMs have begun to plateau when tackling real-world, complex tasks that require interaction with external tools and dynamic environments.…

The localized artificial diffusivity (LAD) method is widely regarded as the preferred multi-material regularization scheme for the compact finite difference method, because it is conservative, easy to implement, and generally robust for a…

Fluid Dynamics · Physics 2025-08-29 Steven R. Brill , Britton J. Olson , Guillaume T. Bokman

Planning is a crucial task for agents in task oriented dialogs (TODs). Human agents typically resolve user issues by following predefined workflows, decomposing workflow steps into actionable items, and performing actions by executing APIs…

Computation and Language · Computer Science 2024-06-06 Shamik Roy , Sailik Sengupta , Daniele Bonadiman , Saab Mansour , Arshit Gupta

This paper introduces "\texttt{TOPress3D}," a 3D topology optimization MATLAB code for structures subjected to design-dependent pressure loads. With a primary focus on pedagogical objectives, the code provides an easy learning experience,…

Computational Engineering, Finance, and Science · Computer Science 2024-12-31 Prabhat Kumar

Topology Optimization (TO), which maximizes structural robustness under material weight constraints, is becoming an essential step for the automatic design of mechanical parts. However, existing TO algorithms use the Finite Element Analysis…

Robotics · Computer Science 2022-04-14 Zherong Pan , Xifeng Gao , Kui Wu

The application of modern topology optimization techniques to single physics systems has seen great advances in the last three decades. However, the application of these tools to sophisticated multiphysics systems such as fluid-structure…

Numerical Analysis · Mathematics 2023-08-11 Mohamed Abdelhamid , Aleksander Czekanski

Neural network compression methods have enabled deploying large models on emerging edge devices with little cost, by adapting already-trained models to the constraints of these devices. The rapid development of AI-capable edge devices with…

Machine Learning · Computer Science 2019-12-20 Soroosh Khoram , Jing Li

Topology optimization(TO) is widely used in engineering because of its ability to save material and optimize structural performance. Although prior work has explored 2D human-centered design tool for TO, the results are often limited in…

Human-Computer Interaction · Computer Science 2026-04-24 Shuyue Feng , Cedric Caremel , Yoshihiro Kawahara

Diffusion models promise efficient parallel text generation but rely on bidirectional attention, creating a structural mismatch with pre-trained Autoregressive (AR) models. This incompatibility precludes reusing robust AR priors,…

Computation and Language · Computer Science 2026-05-29 Xiangyu Ma , Teng Xiao , Zuchao Li , Lefei Zhang

Topology optimization is a widely used design method that produces optimized material distributions for prescribed objectives and constraints through well-established numerical algorithms. Throughout the workflow, engineers make a series of…

Multiagent Systems · Computer Science 2026-05-25 Hyunjee Park , Hayoung Chung

Metal additive manufacturing (AM) processes often fabricate a near-net shape that includes the as-designed part as well as the sacrificial support structures that need to be machined away by subtractive manufacturing (SM), for instance…

Computational Engineering, Finance, and Science · Computer Science 2021-08-09 Amir M. Mirzendehdel , Morad Behandish , Saigopal Nelaturi

Transformation optics (TO) is a new method to design metamaterials that can manipulate electromagnetic fields. Inspired by the traditional TO techniques which is mostly based on the solid metamaterials with a limited range of tunability, a…

Optics · Physics 2026-02-24 R. Yan , Y. Yang , X. Tu , T. Huang , Y. Liu , C. Song

Despite significant advances in generic object detection, a persistent performance gap remains for tiny objects compared to normal-scale objects. We demonstrate that tiny objects are highly sensitive to annotation noise, where optimizing…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Huixin Sun , Linlin Yang , Ronyu Chen , Kerui Gu , Baochang Zhang , Angela Yao , Xianbin Cao

This study proposes a novel topology optimization method for unsteady fluid flows induced by actively moving rigid bodies. The key idea of the proposed method is to decouple the design and analysis domains by using separate grids. The…

Optimization and Control · Mathematics 2025-07-01 Yuta Tanabe , Kentaro Yaji , Kuniharu Ushijima

Three-dimensional topology optimization (TO) is a powerful technique in engineering design, but readily usable, open-source implementations remain limited within the popular Python scientific environment. This paper introduces PyTopo3D, a…

Graphics · Computer Science 2025-04-09 Jihoon Kim , Namwoo Kang

The integration of dynamic, sparse structures like Mixture-of-Experts (MoE) with parameter-efficient adapters (e.g., LoRA) is a powerful technique for enhancing Large Language Models (LLMs). However, this architectural enhancement comes at…

Artificial Intelligence · Computer Science 2026-03-13 Qiyang Li , Rui Kong , Yuchen Li , Hengyi Cai , Shuaiqiang Wang , Linghe Kong , Guihai Chen , Dawei Yin

We introduce a simultaneous and meshfree topology optimization (TO) framework based on physics-informed Gaussian processes (GPs). Our framework endows all design and state variables via GP priors which have a shared, multi-output mean…

Machine Learning · Computer Science 2025-03-21 Amin Yousefpour , Shirin Hosseinmardi , Xiangyu Sun , Ramin Bostanabad

A stable added-mass partitioned (AMP) algorithm is developed for fluid-structure interaction (FSI) problems involving viscous incompressible flow and compressible elastic solids. Deforming composite grids are used to effectively handle the…

Numerical Analysis · Mathematics 2019-10-23 Daniel A. Serino , Jeffrey W. Banks , William D. Henshaw , Donald W. Schwendeman