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Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

Accurate and early diagnosis of malignant melanoma is critical for improving patient outcomes. While convolutional neural networks (CNNs) have shown promise in dermoscopic image analysis, they often neglect clinical metadata and require…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Jihyun Moon , Charmgil Hong

Large Vision-Language Models (LVLMs) have made remarkable strides in multimodal tasks such as visual question answering, visual grounding, and complex reasoning. However, they remain limited by static training data, susceptibility to…

Artificial Intelligence · Computer Science 2025-08-27 Chan-Wei Hu , Yueqi Wang , Shuo Xing , Chia-Ju Chen , Suofei Feng , Ryan Rossi , Zhengzhong Tu

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

With the rapid advancement of multimodal information retrieval, increasingly complex retrieval tasks have emerged. Existing methods predominately rely on task-specific fine-tuning of vision-language models, often those trained with…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Yikun Liu , Pingan Chen , Jiayin Cai , Xiaolong Jiang , Yao Hu , Jiangchao Yao , Yanfeng Wang , Weidi Xie

Medical large vision-language Models (Med-LVLMs) have shown promise in clinical applications but suffer from factual inaccuracies and unreliable outputs, posing risks in real-world diagnostics. While RAG has emerged as a potential solution,…

Computation and Language · Computer Science 2026-05-05 Zhe Chen , Yusheng Liao , Zhiyuan Zhu , Haolin Li , Hongcheng Liu , Yanfeng Wang , Yu Wang

Although Vision Language Models (VLMs) have shown strong generalization in medical imaging, pathology presents unique challenges due to ultra-high resolution, complex tissue structures, and nuanced clinical semantics. These factors make…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Jingru Guo , Hengzhe Zhang , Penghao Zhang , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

The scaling of large language models to encode all the world's knowledge in model parameters is unsustainable and has exacerbated resource barriers. Retrieval-Augmented Generation (RAG) presents a potential solution, yet its application to…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Varun Nagaraj Rao , Siddharth Choudhary , Aditya Deshpande , Ravi Kumar Satzoda , Srikar Appalaraju

Multimodal Retrieval-Augmented Generation (MRAG) enhances large language models (LLMs) by integrating multimodal data (text, images, videos) into retrieval and generation processes, overcoming the limitations of text-only…

Information Retrieval · Computer Science 2025-04-15 Lang Mei , Siyu Mo , Zhihan Yang , Chong Chen

Large language models equipped with retrieval-augmented generation (RAG) represent a burgeoning field aimed at enhancing answering capabilities by leveraging external knowledge bases. Although the application of RAG with language-only…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Cheng Tan , Jingxuan Wei , Linzhuang Sun , Zhangyang Gao , Siyuan Li , Bihui Yu , Ruifeng Guo , Stan Z. Li

Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Lehan Wang , Yi Qin , Honglong Yang , Xiaomeng Li

Current vision-language models (VLMs) still exhibit inferior performance on knowledge-intensive tasks, primarily due to the challenge of accurately encoding all the associations between visual objects and scenes to their corresponding…

Computation and Language · Computer Science 2024-10-16 Jingyuan Qi , Zhiyang Xu , Rulin Shao , Yang Chen , Jin Di , Yu Cheng , Qifan Wang , Lifu Huang

Large Language Models (LLMs) have demonstrated impressive capabilities in answering questions, but they lack domain-specific knowledge and are prone to hallucinations. Retrieval Augmented Generation (RAG) is one approach to address these…

Computation and Language · Computer Science 2024-10-30 Monica Riedler , Stefan Langer

Retrieval-augmented generation (RAG) is a paradigm that augments large language models (LLMs) with external knowledge to tackle knowledge-intensive question answering. While several benchmarks evaluate Multimodal LLMs (MLLMs) under…

Computation and Language · Computer Science 2025-08-18 Yin Wu , Quanyu Long , Jing Li , Jianfei Yu , Wenya Wang

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Vision-and-language multi-modal pretraining and fine-tuning have shown great success in visual question answering (VQA). Compared to general domain VQA, the performance of biomedical VQA suffers from limited data. In this paper, we propose…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Zheng Yuan , Qiao Jin , Chuanqi Tan , Zhengyun Zhao , Hongyi Yuan , Fei Huang , Songfang Huang

Radiology Report Generation (RRG) through Vision-Language Models (VLMs) promises to reduce documentation burden, improve reporting consistency, and accelerate clinical workflows. However, their clinical adoption remains limited by the lack…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Marco Salmè , Federico Siciliano , Fabrizio Silvestri , Paolo Soda , Rosa Sicilia , Valerio Guarrasi

Multimodal document question answering requires retrieving dispersed evidence from visually rich long documents and performing reliable reasoning over heterogeneous information. Existing multimodal RAG systems remain limited by two…

Information Retrieval · Computer Science 2026-03-18 Jiashu Yang , Chi Zhang , Abudukelimu Wuerkaixi , Xuxin Cheng , Cao Liu , Ke Zeng , Xu Jia , Xunliang Cai
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