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Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

With the rapid advancement of retrieval-augmented vision-language models, multimodal medical retrieval-augmented generation (MMed-RAG) systems are increasingly adopted in clinical decision support. These systems enhance medical applications…

Cryptography and Security · Computer Science 2025-11-25 Yingjia Shang , Yi Liu , Huimin Wang , Furong Li , Wenfang Sun , Wu Chengyu , Yefeng Zheng

Retrieval-augmented generation (RAG) is a widely adopted paradigm for enhancing LLMs in medical applications by incorporating expert multimodal knowledge during generation. However, the underlying retrieval databases may naturally contain,…

Cryptography and Security · Computer Science 2026-05-12 Peiru Yang , Haoran Zheng , Tong Ju , Shiting Wang , Wanchun Ni , Jiajun Liu , Shangguang Wang , Yongfeng Huang , Tao Qi

Multimodal retrieval-augmented generation (RAG) enhances the visual reasoning capability of vision-language models (VLMs) by dynamically accessing information from external knowledge bases. In this work, we introduce \textit{Poisoned-MRAG},…

Cryptography and Security · Computer Science 2025-03-17 Yinuo Liu , Zenghui Yuan , Guiyao Tie , Jiawen Shi , Pan Zhou , Lichao Sun , Neil Zhenqiang Gong

Multimodal Large Language Models (MLLMs) have shown impressive performance in vision and text tasks. However, hallucination remains a major challenge, especially in fields like healthcare where details are critical. In this work, we show…

Computation and Language · Computer Science 2025-02-24 Yun-Wei Chu , Kai Zhang , Christopher Malon , Martin Renqiang Min

Medical large vision-language Models (Med-LVLMs) have shown promise in clinical applications but suffer from factual inaccuracies and unreliable outputs, posing risks in real-world diagnostics. While RAG has emerged as a potential solution,…

Computation and Language · Computer Science 2026-05-05 Zhe Chen , Yusheng Liao , Zhiyuan Zhu , Haolin Li , Hongcheng Liu , Yanfeng Wang , Yu Wang

Security concerns related to Large Language Models (LLMs) have been extensively explored, yet the safety implications for Multimodal Large Language Models (MLLMs), particularly in medical contexts (MedMLLMs), remain insufficiently studied.…

Cryptography and Security · Computer Science 2024-08-22 Xijie Huang , Xinyuan Wang , Hantao Zhang , Yinghao Zhu , Jiawen Xi , Jingkun An , Hao Wang , Hao Liang , Chengwei Pan

Multi-Modal Language Models (MLLMs) have transformed artificial intelligence by combining visual and text data, making applications like image captioning, visual question answering, and multi-modal content creation possible. This ability to…

Cryptography and Security · Computer Science 2024-11-11 Pete Janowczyk , Linda Laurier , Ave Giulietta , Arlo Octavia , Meade Cleti

Retrieval-Augmented Generation (RAG) systems enhance response credibility and traceability by displaying reference contexts, but this transparency simultaneously introduces a novel black-box attack vector. Existing document poisoning…

Computation and Language · Computer Science 2026-01-27 Runqi Sui

Vision language models (VLMs) extend the reasoning capabilities of large language models (LLMs) to cross-modal settings, yet remain highly vulnerable to multimodal jailbreak attacks. Existing defenses predominantly rely on safety…

Artificial Intelligence · Computer Science 2026-04-14 Mengxuan Wang , Yuxin Chen , Gang Xu , Tao He , Hongjie Jiang , Ming Li

Large Language Models (LLMs) have demonstrated impressive capabilities in answering questions, but they lack domain-specific knowledge and are prone to hallucinations. Retrieval Augmented Generation (RAG) is one approach to address these…

Computation and Language · Computer Science 2024-10-30 Monica Riedler , Stefan Langer

Retrieval-Augmented Generation (RAG) systems have emerged as a promising solution to mitigate LLM hallucinations and enhance their performance in knowledge-intensive domains. However, these systems are vulnerable to adversarial poisoning…

Information Retrieval · Computer Science 2025-07-29 Jinyan Su , Jin Peng Zhou , Zhengxin Zhang , Preslav Nakov , Claire Cardie

Retrieval-augmented generation (RAG) has become a common practice in multimodal large language models (MLLM) to enhance factual grounding and reduce hallucination. Yet, its reliance on retrieval exposes MLLMs to knowledge poisoning attacks,…

Multimodal large language models (MLLMs) are pushing recommender systems (RecSys) toward content-grounded retrieval and ranking via cross-modal fusion. We find that while cross-modal consensus often mitigates conventional poisoning that…

Cryptography and Security · Computer Science 2026-02-09 Guowei Guan , Yurong Hao , Jiaming Zhang , Tiantong Wu , Fuyao Zhang , Tianxiang Chen , Longtao Huang , Cyril Leung , Wei Yang Bryan Lim

Multimodal Large Language Models (MLLMs) have significantly advanced AI-assisted medical diagnosis, but they often generate factually inconsistent responses that deviate from established medical knowledge. Retrieval-Augmented Generation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Jinhong Wang , Tajamul Ashraf , Zongyan Han , Jorma Laaksonen , Rao Mohammad Anwer

Retrieval-Augmented Generation (RAG) systems, which integrate Large Language Models (LLMs) with external knowledge sources, are vulnerable to a range of adversarial attack vectors. This paper examines the importance of RAG systems through…

Cryptography and Security · Computer Science 2025-06-03 Chris M. Ward , Josh Harguess

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

While Multimodal Large Language Models (MLLMs) show remarkable capabilities, their safety alignments are susceptible to jailbreak attacks. Existing attack methods typically focus on text-image interplay, treating the visual modality as a…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Yuan Xiong , Ziqi Miao , Lijun Li , Chen Qian , Jie Li , Jing Shao

Misdiagnosis causes significant harm to healthcare systems worldwide, leading to increased costs and patient risks. MedRAG is a smart multimodal healthcare copilot equipped with powerful large language model (LLM) reasoning, designed to…

Artificial Intelligence · Computer Science 2025-06-04 Xuejiao Zhao , Siyan Liu , Su-Yin Yang , Chunyan Miao

Medical retrieval-augmented generation (RAG) systems typically operate on text chunks extracted from biomedical literature, discarding the rich visual content (tables, figures, structured layouts) of original document pages. We propose…

Artificial Intelligence · Computer Science 2026-05-01 Xupeng Chen , Binbin Shi , Chenqian Le , Jiaqi Zhang , Kewen Wang , Ran Gong , Jinhan Zhang , Chihang Wang
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