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Large Language Models (LLMs) encounter challenges with the unique syntax of specific domains, such as biomolecules. Existing fine-tuning or modality alignment techniques struggle to bridge the domain knowledge gap and understand complex…

Biomolecules · Quantitative Biology 2024-06-28 Jinzhe Liu , Xiangsheng Huang , Zhuo Chen , Yin Fang

The significant progress of large language models (LLMs) provides a promising opportunity to build human-like systems for various practical applications. However, when applied to specific task domains, an LLM pre-trained on a…

Information Retrieval · Computer Science 2023-11-21 Jing Yao , Wei Xu , Jianxun Lian , Xiting Wang , Xiaoyuan Yi , Xing Xie

Large Language Models (LLMs) have demonstrated remarkable success in various tasks such as natural language understanding, text summarization, and machine translation. However, their general-purpose nature often limits their effectiveness…

Computation and Language · Computer Science 2025-09-03 Zirui Song , Bin Yan , Yuhan Liu , Miao Fang , Mingzhe Li , Rui Yan , Xiuying Chen

Large Language Models (LLMs) perform well in general QA but often struggle in domain-specific scenarios. Retrieval-Augmented Generation (RAG) introduces external knowledge but suffers from hallucinations and latency due to noisy retrievals.…

Computation and Language · Computer Science 2025-09-19 Bolei He , Xinran He , Run Shao , Shanfu Shu , Xianwei Xue , Mingquan Cheng , Haifeng Li , Zhenhua Ling

Large language models (LLMs) excel at general programming but struggle with domain-specific software development, necessitating domain specialization methods for LLMs to learn and utilize domain knowledge and data. However, existing…

Software Engineering · Computer Science 2026-04-28 Xue Jiang , Ge Li , Jiaru Qian , Xianjie Shi , Chenjie Li , Hao Zhu , Ziyu Wang , Jielun Zhang , Zheyu Zhao , Lingwei Wu , Kechi Zhang , Jia Li , Wenpin Jiao , Zhi Jin , Yihong Dong

While Large language models (LLMs) have demonstrated considerable capabilities across various natural language tasks, they often fall short of the performance achieved by domain-specific state-of-the-art models. One potential approach to…

Computation and Language · Computer Science 2024-06-19 An Liu , Zonghan Yang , Zhenhe Zhang , Qingyuan Hu , Peng Li , Ming Yan , Ji Zhang , Fei Huang , Yang Liu

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Retrieval Augmented Generation (RAG) is a technique used to augment Large Language Models (LLMs) with contextually relevant, time-critical, or domain-specific information without altering the underlying model parameters. However,…

Information Retrieval · Computer Science 2024-08-20 Laurent Mombaerts , Terry Ding , Adi Banerjee , Florian Felice , Jonathan Taws , Tarik Borogovac

Large language models (LLMs) have showcased their capability with few-shot inference known as in-context learning. However, in-domain demonstrations are not always readily available in real scenarios, leading to cross-domain in-context…

Computation and Language · Computer Science 2023-11-21 Quanyu Long , Wenya Wang , Sinno Jialin Pan

Applying existing question answering (QA) systems to specialized domains like law and finance presents challenges that necessitate domain expertise. Although large language models (LLMs) have shown impressive language comprehension and…

Computation and Language · Computer Science 2023-10-24 Vaibhav Mavi , Abulhair Saparov , Chen Zhao

Large language models (LLMs) often exhibit limited performance on domain-specific tasks due to the natural disproportionate representation of specialized information in their training data and the static nature of these datasets. Knowledge…

Computation and Language · Computer Science 2025-09-30 Chaojun Nie , Jun Zhou , Guanxiang Wang , Shisong Wu , Zichen Wang

The deployment and application of Large Language Models (LLMs) is hindered by their memory inefficiency, computational demands, and the high costs of API inferences. Traditional distillation methods, which transfer the capabilities of LLMs…

Computation and Language · Computer Science 2024-11-21 Yifei Zhang , Bo Pan , Chen Ling , Yuntong Hu , Liang Zhao

Large Language Models (LLMs), despite their great power in language generation, often encounter challenges when dealing with intricate and knowledge-demanding queries in specific domains. This paper introduces a novel approach to enhance…

Computation and Language · Computer Science 2023-11-20 Ruohong Zhang , Luyu Gao , Chen Zheng , Zhen Fan , Guokun Lai , Zheng Zhang , Fangzhou Ai , Yiming Yang , Hongxia Yang

Logs play a critical role in providing essential information for system monitoring and troubleshooting. Recently, with the success of pre-trained language models (PLMs) and large language models (LLMs) in natural language processing (NLP),…

Software Engineering · Computer Science 2025-02-03 Lipeng Ma , Weidong Yang , Sihang Jiang , Ben Fei , Mingjie Zhou , Shuhao Li , Mingyu Zhao , Bo Xu , Yanghua Xiao

Knowledge enhanced pre-trained language models (K-PLMs) are shown to be effective for many public tasks in the literature but few of them have been successfully applied in practice. To address this problem, we propose K-AID, a systematic…

Artificial Intelligence · Computer Science 2021-09-23 Fu Sun , Feng-Lin Li , Ruize Wang , Qianglong Chen , Xingyi Cheng , Ji Zhang

The widespread adoption of Large Language Models (LLMs) for code generation, exemplified by GitHub Copilot\footnote{A coding extension powered by a Code-LLM to assist in code completion tasks} surpassing a million users, highlights the…

Software Engineering · Computer Science 2025-05-13 Ilyas Oulkadda , Julien Perez

Large Language Models (LLMs) are highly accurate in classification tasks, however, substantial computational and financial costs hinder their large-scale deployment in dynamic environments. Knowledge Distillation (KD) where a LLM "teacher"…

Machine Learning · Computer Science 2025-11-18 Viviana Luccioli , Rithika Iyengar , Ryan Panley , Flora Haberkorn , Xiaoyu Ge , Leland Crane , Nitish Sinha , Seung Jung Lee

Recent advancements in large language models (LLMs) have achieved promising performances across various applications. Nonetheless, the ongoing challenge of integrating long-tail knowledge continues to impede the seamless adoption of LLMs in…

Computation and Language · Computer Science 2024-10-21 Dawei Li , Shu Yang , Zhen Tan , Jae Young Baik , Sukwon Yun , Joseph Lee , Aaron Chacko , Bojian Hou , Duy Duong-Tran , Ying Ding , Huan Liu , Li Shen , Tianlong Chen

Digital health analytics face critical challenges nowadays. The sophisticated analysis of patient-generated health content, which contains complex emotional and medical contexts, requires scarce domain expertise, while traditional ML…

Traditional methods for evaluating the robustness of large language models (LLMs) often rely on standardized benchmarks, which can escalate costs and limit evaluations across varied domains. This paper introduces a novel framework designed…

Computation and Language · Computer Science 2024-12-03 Aihua Pei , Zehua Yang , Shunan Zhu , Ruoxi Cheng , Ju Jia
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