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Reinforcement Learning (RL) in environments with complex, history-dependent reward structures poses significant challenges for traditional methods. In this work, we introduce a novel approach that leverages automaton-based feedback to guide…

Machine Learning · Computer Science 2025-10-20 Mahyar Alinejad , Alvaro Velasquez , Yue Wang , George Atia

Denoising diffusion probabilistic models (DDPMs) are a recent family of generative models that achieve state-of-the-art results. In order to obtain class-conditional generation, it was suggested to guide the diffusion process by gradients…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Bahjat Kawar , Roy Ganz , Michael Elad

Diffusion models have emerged as powerful generative tools across various domains, yet tailoring pre-trained models to exhibit specific desirable properties remains challenging. While reinforcement learning (RL) offers a promising…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Fengyuan Dai , Zifeng Zhuang , Yufei Huang , Siteng Huang , Bangyan Liao , Donglin Wang , Fajie Yuan

Reinforcement Learning (RL) is a general framework concerned with an agent that seeks to maximize rewards in an environment. The learning typically happens through trial and error using explorative methods, such as epsilon-greedy. There are…

Machine Learning · Computer Science 2022-10-06 Per-Arne Andersen , Morten Goodwin , Ole-Christoffer Granmo

Latent diffusion models are the state-of-the-art for synthetic image generation. To align these models with human preferences, training the models using reinforcement learning on human feedback is crucial. Black et. al 2024 introduced…

Machine Learning · Computer Science 2024-04-09 Mo Kordzanganeh , Danial Keshvary , Nariman Arian

Large reasoning models (LRMs) aim to solve diverse and complex problems through structured reasoning. Recent advances in group-based policy optimization methods have shown promise in enabling stable advantage estimation without reliance on…

Machine Learning · Computer Science 2026-01-29 Zhizheng Jiang , Kang Zhao , Weikai Xu , Xinkui Lin , Wei Liu , Jian Luan , Shuo Shang , Peng Han

Developing bioactive molecules remains a central, time- and cost-heavy challenge in drug discovery, particularly for novel targets lacking structural or functional data. Pharmacophore modeling presents an alternative for capturing the key…

Machine Learning · Computer Science 2025-05-16 Amira Alakhdar , Barnabas Poczos , Newell Washburn

Diffusion-based large language models offer a non-autoregressive alternative for text generation, but enabling them to perform complex reasoning remains challenging. Reinforcement learning has recently emerged as an effective post-training…

Artificial Intelligence · Computer Science 2026-04-14 Shaoan Xie , Lingjing Kong , Xiangchen Song , Xinshuai Dong , Guangyi Chen , Eric P. Xing , Kun Zhang

Building virtual cells with generative models to simulate cellular behavior in silico is emerging as a promising paradigm for accelerating drug discovery. However, prior image-based generative approaches can produce implausible cell images…

Machine Learning · Computer Science 2026-05-22 Dongxia Wu , Shiye Su , Yuhui Zhang , Elaine Sui , Emma Lundberg , Emily B. Fox , Serena Yeung-Levy

Recent advancements in controllable text-to-image (T2I) diffusion models, such as Ctrl-X and FreeControl, have demonstrated robust spatial and appearance control without requiring auxiliary module training. However, these models often…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Jiwon Kim , Pureum Kim , SeonHwa Kim , Soobin Park , Eunju Cha , Kyong Hwan Jin

We propose Inner Loop Feedback (ILF), a novel approach to accelerate diffusion models' inference. ILF trains a lightweight module to predict future features in the denoising process by leveraging the outputs from a chosen diffusion backbone…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Matthew Gwilliam , Han Cai , Di Wu , Abhinav Shrivastava , Zhiyu Cheng

Generalizing locomotion policies across diverse legged robots with varying morphologies is a key challenge due to differences in observation/action dimensions and system dynamics. In this work, we propose Multi-Loco, a novel unified…

Robotics · Computer Science 2025-06-16 Shunpeng Yang , Zhen Fu , Zhefeng Cao , Guo Junde , Patrick Wensing , Wei Zhang , Hua Chen

Diffusion models achieve state-of-the-art generative performance but are fundamentally bottlenecked by their slow, iterative sampling process. While diffusion distillation techniques enable high-fidelity, few-step generation, traditional…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Linqian Fan , Peiqin Sun , Tiancheng Wen , Shun Lu , Chengru Song

Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso

Classifier-free guidance (CFG) is a cornerstone of text-to-image diffusion models, yet its effectiveness is limited by the use of static guidance scales. This "one-size-fits-all" approach fails to adapt to the diverse requirements of…

Machine learning has demonstrated remarkable promise for solving the trajectory generation problem and in paving the way for online use of trajectory optimization for resource-constrained spacecraft. However, a key shortcoming in current…

Robotics · Computer Science 2025-01-03 Julia Briden , Breanna Johnson , Richard Linares , Abhishek Cauligi

Reinforcement Learning with Verifiable Rewards (RLVR) has recently emerged as a promising framework for improving reasoning abilities in Large Language Models (LLMs). However, policy optimized with binary verification prone to overlook…

Machine Learning · Computer Science 2025-10-14 Jinghao Zhang , Naishan Zheng , Ruilin Li , Dongzhou Cheng , Zheming Liang , Feng Zhao , Jiaqi Wang

Diffusion models have been successfully applied in areas such as image, video, and audio generation. Recent works show their promise for sequential decision-making and dexterous manipulation, leveraging their ability to model complex action…

Robotics · Computer Science 2026-03-17 Maria Makarova , Qian Liu , Dzmitry Tsetserukou

Diffusion has emerged as a powerful framework for generative modeling, achieving remarkable success in applications such as image and audio synthesis. Enlightened by this progress, we propose a novel diffusion-based approach for symbolic…

Machine Learning · Computer Science 2025-06-02 Zachary Bastiani , Robert M. Kirby , Jacob Hochhalter , Shandian Zhe

The discovery of inorganic crystal structures with targeted properties is a significant challenge in materials science. Generative models, especially state-of-the-art diffusion models, offer the promise of modeling complex data…