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Scientific Machine Learning is a new class of approaches that integrate physical knowledge and mechanistic models with data-driven techniques for uncovering governing equations of complex processes. Among the available approaches, Universal…

Machine Learning · Statistics 2024-06-14 Nina Schmid , David Fernandes del Pozo , Willem Waegeman , Jan Hasenauer

Following a series of high-profile drug safety disasters in recent years, many countries are redoubling their efforts to ensure the safety of licensed medical products. Large-scale observational databases such as claims databases or…

Computation · Statistics 2012-08-07 Marc A. Suchard , Shawn E. Simpson , Ivan Zorych , Patrick Ryan , David Madigan

Present-day quantum systems face critical bottlenecks, including limited qubit counts, brief coherence intervals, and high susceptibility to errors-all of which obstruct the execution of large and complex circuits. The advancement of…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-13 Waylon Luo , Jiapeng Zhao , Tong Zhan , Qiang Guan

Traditional machine learning relies on explicit models and domain assumptions, limiting flexibility and interpretability. We introduce a model-free framework using surprisal (information theoretic uncertainty) to directly analyze and…

Our understanding of physical systems generally depends on our ability to match complex computational modelling with measured experimental outcomes. However, simulations with large parameter spaces suffer from inverse problem instabilities,…

Plasma Physics · Physics 2020-01-22 M. F. Kasim , T. P. Galligan , J. Topp-Mugglestone , G. Gregori , S. M. Vinko

The increased availability of massive data sets provides a unique opportunity to discover subtle patterns in their distributions, but also imposes overwhelming computational challenges. To fully utilize the information contained in big…

Statistics Theory · Mathematics 2018-04-12 Stanislav Volgushev , Shih-Kang Chao , Guang Cheng

The past century has seen a steady increase in the need of estimating and predicting complex systems and making (possibly critical) decisions with limited information. Although computers have made possible the numerical evaluation of…

Statistics Theory · Mathematics 2017-01-13 Houman Owhadi , Clint Scovel

Background: With the rapid growth of massively parallel sequencing technologies, still more laboratories are utilizing sequenced DNA fragments for genomic analyses. Interpretation of sequencing data is, however, strongly dependent on…

The quantification of social science remains a longstanding challenge, largely due to the philosophical nature of its foundational theories. Although quantum computing has advanced rapidly in recent years, its relevance to social theory…

Artificial Intelligence · Computer Science 2025-06-05 Shan Shan

The comprehensive integration of machine learning healthcare models within clinical practice remains suboptimal, notwithstanding the proliferation of high-performing solutions reported in the literature. A predominant factor hindering…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Ling Huang , Su Ruan , Yucheng Xing , Mengling Feng

The digital twin concept represents an appealing opportunity to advance condition-based and predictive maintenance paradigms for civil engineering systems, thus allowing reduced lifecycle costs, increased system safety, and increased system…

Numerical Analysis · Mathematics 2023-11-10 Matteo Torzoni , Marco Tezzele , Stefano Mariani , Andrea Manzoni , Karen E. Willcox

We introduce the concept of a Graph-Informed Neural Network (GINN), a hybrid approach combining deep learning with probabilistic graphical models (PGMs) that acts as a surrogate for physics-based representations of multiscale and…

Computational Physics · Physics 2021-03-17 Eric J. Hall , Søren Taverniers , Markos A. Katsoulakis , Daniel M. Tartakovsky

Physics-Informed Neural Networks (PINNs) are gaining popularity as a method for solving differential equations. While being more feasible in some contexts than the classical numerical techniques, PINNs still lack credibility. A remedy for…

Machine Learning · Computer Science 2022-12-15 Olga Graf , Pablo Flores , Pavlos Protopapas , Karim Pichara

In this work, we propose a framework in the form of a Python package, specifically designed for the analysis of Quantum Machine Learning models. This framework is based on the PennyLane simulator and facilitates the evaluation and training…

Quantum Physics · Physics 2025-09-17 Melvin Strobl , Maja Franz , Eileen Kuehn , Wolfgang Mauerer , Achim Streit

Recently Quantum Computation has generated a lot of interest due to the discovery of a quantum algorithm which can factor large numbers in polynomial time. The usefulness of a quantum com puter is limited by the effect of errors. Simulation…

Quantum Physics · Physics 2007-05-23 Kevin M. Obenland , Alvin M. Despain

Uncertainty Quantification (UQ) is a booming discipline for complex computational models based on the analysis of robustness, reliability and credibility. UQ analysis for nonlinear crash models with high dimensional outputs presents…

Computational Engineering, Finance, and Science · Computer Science 2021-03-31 Marc Rocas , Alberto García-González , Xabier Larrayoz , Pedro Díez

This study investigates uncertainty quantification (UQ) using quantum-classical hybrid machine learning (ML) models for applications in complex and dynamic fields, such as attaining resiliency in supply chain digital twins and financial…

Recent advancements in DeepFake generation, along with the proliferation of open-source tools, have significantly lowered the barrier for creating synthetic media. This trend poses a serious threat to the integrity and authenticity of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Spiros Baxavanakis , Manos Schinas , Symeon Papadopoulos

Debugging performance anomalies in real-world databases is challenging. Causal inference techniques enable qualitative and quantitative root cause analysis of performance downgrade. Nevertheless, causality analysis is practically…

Databases · Computer Science 2023-09-15 Zhenlan Ji , Pingchuan Ma , Shuai Wang

Quantum computers provide an opportunity to efficiently sample from probability distributions that include non-trivial interference effects between amplitudes. Using a simple process wherein all possible state histories can be specified by…

Quantum Physics · Physics 2019-08-22 Davide Provasoli , Benjamin Nachman , Wibe A. de Jong , Christian W Bauer
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