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When using machine learning for imbalanced binary classification problems, it is common to subsample the majority class to create a (more) balanced training dataset. This biases the model's predictions because the model learns from data…

Machine Learning · Computer Science 2025-11-03 Nathan Phelps , Daniel J. Lizotte , Douglas G. Woolford

In prevalent cohort studies with delayed entry, time-to-event outcomes are often subject to left truncation where only subjects that have not experienced the event at study entry are included, leading to selection bias. Existing methods for…

Methodology · Statistics 2025-12-25 Yuyao Wang , Andrew Ying , Ronghui Xu

Standard supervised learning procedures are validated against a test set that is assumed to have come from the same distribution as the training data. However, in many problems, the test data may have come from a different distribution. We…

Machine Learning · Statistics 2019-08-28 Tim Coleman , Kimberly Kaufeld , Mary Frances Dorn , Lucas Mentch

Regression methods for interval-valued data have been increasingly studied in recent years. As most of the existing works focus on linear models, it is important to note that many problems in practice are nonlinear in nature and therefore…

Methodology · Statistics 2022-01-11 Chih-Ching Yeh , Yan Sun , Adele Cutler

Right censored survival data collected on a cohort of prevalent cases with constant incidence are length-biased, and may be used to estimate the length-biased (i.e., prevalent-case) survival function. When the incidence rate is constant,…

Statistics Theory · Mathematics 2007-06-13 Masoud Asgharian , David B. Wolfson

Interpretability is crucial for doctors, hospitals, pharmaceutical companies and biotechnology corporations to analyze and make decisions for high stakes problems that involve human health. Tree-based methods have been widely adopted for…

Machine Learning · Computer Science 2024-05-24 Rui Zhang , Rui Xin , Margo Seltzer , Cynthia Rudin

In prevalent cohort studies with follow-up, the time-to-event outcome is subject to left truncation leading to selection bias. For estimation of the distribution of time-to-event, conventional methods adjusting for left truncation tend to…

Methodology · Statistics 2025-12-29 Yuyao Wang , Andrew Ying , Ronghui Xu

We present a conformal inference method for constructing lower prediction bounds for survival times from right-censored data, extending recent approaches designed for more restrictive type-I censoring scenarios. The proposed method imputes…

Methodology · Statistics 2025-05-26 Matteo Sesia , Vladimir Svetnik

In the fight against hard-to-treat diseases such as cancer, it is often difficult to discover new treatments that benefit all subjects. For regulatory agency approval, it is more practical to identify subgroups of subjects for whom the…

Methodology · Statistics 2014-10-09 Wei-Yin Loh , Xu He , Michael Man

In this paper, we investigate right-truncated count data models incorporating cavariates into the parameters. A regression method is proposed to model right-truncated count data exibiting high heterogeneity. The study encompasses the…

Methodology · Statistics 2025-03-11 Babagnidé François Koladjo , Ricardo Anderson Donte , Epiphane Sodjinou

There are many approaches for training decision trees. This work introduces a novel gradient-based method for constructing decision trees that optimize arbitrary differentiable loss functions, overcoming the limitations of heuristic…

Machine Learning · Computer Science 2025-03-25 Andrei V. Konstantinov , Lev V. Utkin

Tree-based ensemble methods, as Random Forests and Gradient Boosted Trees, have been successfully used for regression in many applications and research studies. Furthermore, these methods have been extended in order to deal with uncertainty…

Machine Learning · Computer Science 2018-11-20 Myriam Tami , Marianne Clausel , Emilie Devijver , Adrien Dulac , Eric Gaussier , Stefan Janaqi , Meriam Chebre

Popular parametric and semiparametric hazards regression models for clustered survival data are inappropriate and inadequate when the unknown effects of different covariates and clustering are complex. This calls for a flexible modeling…

Applications · Statistics 2021-03-16 Piyali Basak , Antonio R. Linero , Debajyoti SInha , Stuart Lipsitz

In the context of personalized medicine, machine learning algorithms are growing in popularity. These algorithms require substantial information, which can be acquired effectively through the usage of previously gathered data. Open data and…

Machine Learning · Computer Science 2026-01-13 Niklas Jacobs , Manuel C. Voelkle , Norbert Kathmann , Kevin Hilbert

Precision oncology aims to prescribe the optimal cancer treatment to the right patients, maximizing therapeutic benefits. However, identifying patient subgroups that may benefit more from experimental cancer treatments based on randomized…

Methodology · Statistics 2026-01-06 Xingyu Li , Qing Liu , Tony Jiang , Hong Amy Xia , Peng Wei , Brian P. Hobbs

Longitudinal observational patient data can be used to investigate the causal effects of time-varying treatments on time-to-event outcomes. Several methods have been developed for controlling for the time-dependent confounding that…

Methodology · Statistics 2021-10-08 Ruth H. Keogh , Jon Michael Gran , Shaun R. Seaman , Gwyneth Davies , Stijn Vansteelandt

When dealing with right-censored data, where some outcomes are missing due to a limited observation period, survival analysis -- known as time-to-event analysis -- focuses on predicting the time until an event of interest occurs. Multiple…

Machine Learning · Statistics 2024-10-23 Julie Alberge , Vincent Maladière , Olivier Grisel , Judith Abécassis , Gaël Varoquaux

Survival analysis concerns the task of predicting the time until an event occurs. Often used in the medical field, survival analysis deals with incomplete (i.e., censored) data, for instance, from patients who did not experience the event…

Machine Learning · Computer Science 2026-05-29 Thalea Schlender , Peter A. N. Bosman , Tanja Alderliesten

The lifetimes of subjects which are left-censored lie below a threshold value or a limit of detection. A popular tool used to handle left-censored data is the reversed hazard rate. In this work, we study the properties and develop…

Statistics Theory · Mathematics 2022-12-27 G. Asha , Durga Vasudevan

This paper introduces a Random Survival Forest (RSF) method for functional data. The focus is specifically on defining a new functional data structure, the Censored Functional Data (CFD), for dealing with temporal observations that are…

Methodology · Statistics 2025-02-25 Elvira Romano , Giuseppe Loffredo , Fabrizio Maturo