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Changes in a cell's external or internal conditions are usually reflected in the concentrations of the relevant transcription factors. These proteins in turn modulate the expression levels of the genes under their control and sometimes need…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , Curtis G Callan , William Bialek

Some systems cannot be predicted by classical theories and it is required the development of combined deterministic and stochastic theories that make used of noise for dynamical prediction. Noise is not always an interfering signal which…

Adaptation and Self-Organizing Systems · Physics 2019-05-14 Alexandra Pinto Castellanos

The proliferation of machine learning and artificial intelligence redefines the interaction between the anthropogenic and natural elements of our habitat.The use of monitoring tools, processing facilities and the internet of things supports…

Computers and Society · Computer Science 2026-01-01 Francesca Larosa , Daniel Depellegrin , Andrea Conte , Marco Molinari , Silvia Santato , Adam Wickberg , Fermin Mallor , Anna Sperotto

Biological systems are characterized by the ubiquitous roles of weak, that is, non-covalent molecular interactions, small, often very small, numbers of specific molecules per cell, and Brownian motion. These combine to produce stochastic…

Cell Behavior · Quantitative Biology 2023-04-27 Michael W. Klymkowsky

Order can spontaneously emerge from seemingly noisy interactions between biological agents, like a flock of birds changing their direction of flight in unison, without a leader or an external cue. We are interested in the generic conditions…

Biological Physics · Physics 2021-03-09 Carsten T. van de Kamp , George Dadunashvili , Johan L. A. Dubbeldam , Timon Idema

Nature presents multiple intriguing examples of processes which proceed at high precision and regularity. This remarkable stability is frequently counter to modelers' experience with the inherent stochasticity of chemical reactions in the…

Molecular Networks · Quantitative Biology 2015-12-31 Andreas Milias-Argeitis , Stefan Engblom , Pavol Bauer , Mustafa Khammash

Understanding noisy information engines is a fundamental problem of non-equilibrium physics, particularly in biomolecular systems agitated by thermal and active fluctuations in the cell. By the generalized second law of thermodynamics, the…

Statistical Mechanics · Physics 2020-09-01 Govind Paneru , Sandipan Dutta , Takahiro Sagawa , Tsvi Tlusty , Hyuk Kyu Pak

Cells are constantly exposed to fluctuating environmental conditions. External signals are sensed, processed and integrated by cellular signal transduction networks, which translate input signals into specific cellular responses by means of…

Molecular Networks · Quantitative Biology 2012-05-29 Pau Rué , Núria Domedel-Puig , Jordi Garcia-Ojalvo , Antonio J. Pons

The manner in which groups of neurons represent events in the external world is fundamental to neuroscience. Here, we analyze the population code of the retina during naturalistic stimulation and show that the information conveyed by…

Neurons and Cognition · Quantitative Biology 2007-05-23 Elad Schneidman , Jason L. Puchalla , Ronen Segev , Robert A. Harris , William Bialek , Michael J. Berry

We consider a collection of self-driven apolar particles on a substrate that organize into an active nematic phase at sufficiently high density or low noise. Using the dynamical renormalization group, we systematically study the 2d…

Soft Condensed Matter · Physics 2018-02-07 Suraj Shankar , Sriram Ramaswamy , M. Cristina Marchetti

A new class of energy-efficient digital microprocessor is being developed which is susceptible to thermal noise and consequently operates in probabilistic rather than conventional deterministic mode. Hybrid computing systems which combine…

Neurons and Cognition · Quantitative Biology 2014-12-17 T. N. Palmer , M. O'Shea

Understanding under which conditions the increase of systems complexity is evolutionary advantageous, and how this trend is related to the modulation of the intrinsic noise, are fascinating issues of utmost importance for synthetic and…

Molecular Networks · Quantitative Biology 2018-08-01 Fabrizio Pucci , Marianne Rooman

First return maps of interspike intervals for biological neurons that generate repetitive bursts of impulses can display stereotyped structures (neuronal signatures). Such structures have been linked to the possibility of multicoding and…

Neurons and Cognition · Quantitative Biology 2015-06-22 Bóris Marin , Reynaldo Daniel Pinto , Robert C Elson , Eduardo Colli

We study the effects of noise on the dynamics of a system of coupled self-propelling particles in the case where the coupling is time-delayed, and the delays are discrete and randomly generated. Previous work has demonstrated that the…

Pattern Formation and Solitons · Physics 2012-10-08 Brandon Lindley , Luis Mier-y-Teran-Romero , Ira B. Schwartz

An important characteristic of flocks of birds, school of fish, and many similar assemblies of self-propelled particles is the emergence of states of collective order in which the particles move in the same direction. When noise is added…

Statistical Mechanics · Physics 2015-01-19 M. Aldana , V. Dossetti , C. Huepe , V. M. Kenkre , H. Larralde

We theoretically describe how weak signals may be efficiently transmitted throughout more than one frequency range in noisy excitable media by kind of stochastic multiresonance. This serves us here to reinterpret recent experiments in…

Data Analysis, Statistics and Probability · Physics 2015-05-27 J. J. Torres , J. Marro , J. F. Mejias

Neurons and networks in the cerebral cortex must operate reliably despite multiple sources of noise. To evaluate the impact of both input and output noise, we determine the robustness of single-neuron stimulus selective responses, as well…

Neurons and Cognition · Quantitative Biology 2018-01-24 Ran Rubin , L. F. Abbott , Haim Sompolinsky

This paper investigates the impact of control field noise on the optimal manipulation of quantum dynamics. Simulations are performed on several multilevel quantum systems with the goal of population transfer in the presence of significant…

Chemical Physics · Physics 2009-11-11 Feng Shuang , Herschel Rabitz

We present a theory for describing the evolution of a galaxy caused by stochastic events such as weak mergers, transient spiral structure, orbiting blobs, etc. This noise excites large-scale patterns that drives the evolution of the…

Astrophysics · Physics 2009-10-31 Martin D. Weinberg

The exact microscopic structure of the environments that produces $1/f$ noise in superconducting qubits remains largely unknown, hindering our ability to have robust simulations and harness the noise. In this paper we show how it is…

Quantum Physics · Physics 2022-04-22 Miha Papič , Inés de Vega
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