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A stroke is defined as a neurologic deficit arising from an interruption in blood supply to the brain. According to the World Health Organization, over 15 million people suffer from strokes annually, of which almost 70% die or are…

Quantitative Methods · Quantitative Biology 2022-03-29 Rohan Kalahasty , Lakshmi Sritan Motati

Stroke lesion volume is a key radiologic measurement for assessing the prognosis of Acute Ischemic Stroke (AIS) patients, which is challenging to be automatically measured on Non-Contrast CT (NCCT) scans. Recent diffusion probabilistic…

Computer Vision and Pattern Recognition · Computer Science 2023-07-19 Jianhai Zhang , Tonghua Wan , Ethan MacDonald , Bijoy Menon , Aravind Ganesh , Qiu Wu

Coronary artery disease (CAD), one of the leading causes of mortality worldwide, necessitates effective risk assessment strategies, with coronary artery calcium (CAC) scoring via computed tomography (CT) being a key method for prevention.…

Image and Video Processing · Electrical Eng. & Systems 2026-02-11 Mahmut S. Gokmen , Caner Ozcan , Moneera N. Haque , Steve W. Leung , C. Seth Parker , W. Brent Seales , Cody Bumgardner

White matter hyperintensities (WMH) and ischaemic stroke lesions (ISL) are imaging features associated with cerebral small vessel disease (SVD) that are visible on brain magnetic resonance imaging (MRI) scans. The development and validation…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Jesse Phitidis , Alison Q. Smithard , William N. Whiteley , Joanna M. Wardlaw , Miguel O. Bernabeu , Maria Valdés Hernández

The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…

Purpose: Lesion segmentation in medical imaging is key to evaluating treatment response. We have recently shown that reinforcement learning can be applied to radiological images for lesion localization. Furthermore, we demonstrated that…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Joseph Stember , Hrithwik Shalu

Although numerous improvements have been made in the field of image segmentation using convolutional neural networks, the majority of these improvements rely on training with larger datasets, model architecture modifications, novel loss…

Computer Vision and Pattern Recognition · Computer Science 2019-07-11 Saied Asgari Taghanaki , Kumar Abhishek , Ghassan Hamarneh

In neuroimaging, generally, brain CT is more cost-effective and accessible imaging option compared to MRI. Nevertheless, CT exhibits inferior soft-tissue contrast and higher noise levels, yielding less precise structural clarity. In…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Kyobin Choo , Youngjun Jun , Mijin Yun , Seong Jae Hwang

Cardiovascular disease (CVD) is the leading cause of mortality yet largely preventable, but the key to prevention is to identify at-risk individuals before adverse events. For predicting individual CVD risk, carotid intima-media thickness…

Computer Vision and Pattern Recognition · Computer Science 2017-06-05 Jae Y. Shin , Nima Tajbakhsh , R. Todd Hurst , Christopher B. Kendall , Jianming Liang

Whole Slide Images (WSIs) are giga-pixel in scale and are typically partitioned into small instances in WSI classification pipelines for computational feasibility. However, obtaining extensive instance level annotations is costly, making…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jayanie Bogahawatte , Sachith Seneviratne , Saman Halgamuge

Accurate automatic segmentation of brain anatomy from $T_1$-weighted~($T_1$-w) magnetic resonance images~(MRI) has been a computationally intensive bottleneck in neuroimaging pipelines, with state-of-the-art results obtained by unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Amod Jog , Bruce Fischl

Coronary artery disease remains one of the leading causes of mortality globally. Despite advances in revascularization treatments like PCI and CABG, postoperative stroke is inevitable. This study aims to develop and evaluate a sophisticated…

Machine Learning · Computer Science 2025-03-18 Haonan Pan , Shuheng Chen , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Segmenting stroke lesions in MRI is challenging due to diverse acquisition protocols that limit model generalisability. In this work, we introduce two physics-constrained approaches to generate synthetic quantitative MRI (qMRI) images that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Liam Chalcroft , Jenny Crinion , Cathy J. Price , John Ashburner

Whole-slide images (WSIs) are fundamental for computational pathology, where accurate lesion segmentation is critical for clinical decision making. Existing methods partition WSIs into discrete patches, disrupting spatial continuity and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Yunheng Wu , Wenqi Huang , Liangyi Wang , Masahiro Oda , Yuichiro Hayashi , Daniel Rueckert , Kensaku Mori

Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Peter Bokor , Lukas Hudec , Ondrej Fabian , Wanda Benesova

Diffusion magnetic resonance imaging (MRI) is the only imaging modality for non-invasive movement detection of in vivo water molecules, with significant clinical and research applications. Diffusion weighted imaging (DWI) MRI acquired by…

Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to…

Image and Video Processing · Electrical Eng. & Systems 2019-11-12 Tongda Xu , Xiyan Cai , Yao Wang , Xiuyuan Wang , Sohae Chung , Els Fieremans , Joseph Rath , Steven Flanagan , Yvonne W Lui

Objective: Hydrocephalus is a medical condition in which there is an abnormal accumulation of cerebrospinal fluid (CSF) in the brain. Segmentation of brain imagery into brain tissue and CSF (before and after surgery, i.e. pre-op vs. postop)…

Image and Video Processing · Electrical Eng. & Systems 2018-09-11 Venkateswararao Cherukuri , Peter Ssenyonga , Benjamin C. Warf , Abhaya V. Kulkarni , Vishal Monga , Steven J. Schiff

Diffusion MRI (dMRI) is essential for studying brain microstructure, but high-resolution imaging remains challenging due to the inherent trade-offs between acquisition time and signal-to-noise ratio (SNR). Conventional methods often…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Mengze Gao , Congyu Liao , Guang Yang , Kawin Setsompop

Deep learning has led to state-of-the-art results for many medical imaging tasks, such as segmentation of different anatomical structures. With the increased numbers of deep learning publications and openly available code, the approach to…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Tom van Sonsbeek , Veronika Cheplygina