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Next-generation multimodal foundation models capable of any-to-any cross-modal generation and multi-turn interaction will serve as core components of artificial general intelligence systems, playing a pivotal role in human-machine…

Computation and Language · Computer Science 2025-10-17 Run Luo , Xiaobo Xia , Lu Wang , Longze Chen , Renke Shan , Jing Luo , Min Yang , Tat-Seng Chua

Multimodal Transformers often produce predictions without clarifying how different modalities jointly support a decision. Most existing multimodal explainable AI (MXAI) methods extend unimodal saliency to multimodal backbones, highlighting…

Machine Learning · Computer Science 2026-03-17 Yeji Kim , Housam Khalifa Bashier Babiker , Mi-Young Kim , Randy Goebel

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples…

Machine Learning · Computer Science 2025-09-01 Xiaoyang Wang , Christopher C. Yang

Scientific Large Language Models (Sci-LLMs) are transforming how knowledge is represented, integrated, and applied in scientific research, yet their progress is shaped by the complex nature of scientific data. This survey presents a…

Computation and Language · Computer Science 2025-10-21 Ming Hu , Chenglong Ma , Wei Li , Wanghan Xu , Jiamin Wu , Jucheng Hu , Tianbin Li , Guohang Zhuang , Jiaqi Liu , Yingzhou Lu , Ying Chen , Chaoyang Zhang , Cheng Tan , Jie Ying , Guocheng Wu , Shujian Gao , Pengcheng Chen , Jiashi Lin , Haitao Wu , Lulu Chen , Fengxiang Wang , Yuanyuan Zhang , Xiangyu Zhao , Feilong Tang , Encheng Su , Junzhi Ning , Xinyao Liu , Ye Du , Changkai Ji , Pengfei Jiang , Cheng Tang , Ziyan Huang , Jiyao Liu , Jiaqi Wei , Yuejin Yang , Xiang Zhang , Guangshuai Wang , Yue Yang , Huihui Xu , Ziyang Chen , Yizhou Wang , Chen Tang , Jianyu Wu , Yuchen Ren , Siyuan Yan , Zhonghua Wang , Zhongxing Xu , Shiyan Su , Shangquan Sun , Runkai Zhao , Zhisheng Zhang , Dingkang Yang , Jinjie Wei , Jiaqi Wang , Jiahao Xu , Jiangtao Yan , Wenhao Tang , Hongze Zhu , Yu Liu , Fudi Wang , Yiqing Shen , Yuanfeng Ji , Yanzhou Su , Tong Xie , Hongming Shan , Chun-Mei Feng , Zhi Hou , Diping Song , Lihao Liu , Yanyan Huang , Lequan Yu , Bin Fu , Shujun Wang , Xiaomeng Li , Xiaowei Hu , Yun Gu , Ben Fei , Benyou Wang , Yuewen Cao , Minjie Shen , Jie Xu , Haodong Duan , Fang Yan , Hongxia Hao , Jielan Li , Jiajun Du , Yanbo Wang , Imran Razzak , Zhongying Deng , Chi Zhang , Lijun Wu , Conghui He , Zhaohui Lu , Jinhai Huang , Wenqi Shao , Yihao Liu , Siqi Luo , Yi Xin , Xiaohong Liu , Fenghua Ling , Yuqiang Li , Aoran Wang , Siqi Sun , Qihao Zheng , Nanqing Dong , Tianfan Fu , Dongzhan Zhou , Yan Lu , Wenlong Zhang , Jin Ye , Jianfei Cai , Yirong Chen , Wanli Ouyang , Yu Qiao , Zongyuan Ge , Shixiang Tang , Junjun He , Chunfeng Song , Lei Bai , Bowen Zhou

We propose to build omni-modal intelligence, which is capable of understanding any modality and learning universal representations. In specific, we propose a scalable pretraining paradigm, named Multimodal Context (MiCo), which can scale up…

Computer Vision and Pattern Recognition · Computer Science 2024-06-14 Yiyuan Zhang , Handong Li , Jing Liu , Xiangyu Yue

In the molecular domain, numerous studies have explored the use of multimodal large language models (LLMs) to construct a general-purpose, multi-task molecular model. However, these efforts are still far from achieving a truly universal…

Machine Learning · Computer Science 2025-10-31 Chengxin Hu , Hao Li , Yihe Yuan , Zezheng Song , Chenyang Zhao , Haixin Wang

Large Language Models (LLMs) are central to the one-for-all intelligent paradigm, but they face a fundamental challenge when dealing with heterogeneous scientific data such as molecules: the inherent gap between discrete linguistic symbols…

Artificial Intelligence · Computer Science 2026-05-22 Yuxuan Chen , Changwei Lv , Yunduo Xiao , Zhongjing Du , Daquan Zhou , Yukun Yan , Zheni Zeng , Zhiyuan Liu

Large foundation models (FMs) are transforming Earth science by integrating heterogeneous multimodal data, such as multi-platform imagery, gridded reanalysis data, diverse geophysical and geochemical observations, and domain-specific text,…

Instrumentation and Methods for Astrophysics · Physics 2026-05-14 Xiangyu Zhao , Bo Liu , Yuehan Zhang , Zelin Song , Wanghan Xu , Feng Liu , Fengxiang Wang , Ben Fei , Fenghua Ling , Wangxu Wei , Wenlong Zhang , Xiao-Ming Wu

Large language models like ChatGPT have shown substantial progress in natural language understanding and generation, proving valuable across various disciplines, including the medical field. Despite advancements, challenges persist due to…

Computation and Language · Computer Science 2024-04-16 Yusheng Liao , Shuyang Jiang , Yu Wang , Yanfeng Wang

Mixture of Experts (MoE) architectures have emerged as pivotal for scaling Large Language Models (LLMs) efficiently. Fine-grained MoE approaches - utilizing more numerous, smaller experts - have demonstrated potential in improving model…

Machine Learning · Computer Science 2025-06-04 Jakub Krajewski , Marcin Chochowski , Daniel Korzekwa

Multimodal Large Languages models have been progressing from uni-modal understanding toward unifying visual, audio and language modalities, collectively termed omni models. However, the correlation between uni-modal and omni-modal remains…

Computation and Language · Computer Science 2025-10-31 Chen Chen , ZeYang Hu , Fengjiao Chen , Liya Ma , Jiaxing Liu , Xiaoyu Li , Ziwen Wang , Xuezhi Cao , Xunliang Cai

Computational models have become one of the prevalent methods to model complex phenomena. To accurately model complex interactions, such as detailed biomolecular interactions, scientists often rely on multiscale models comprised of several…

Multi-modal co-learning is emerging as an effective paradigm in machine learning, enabling models to collaboratively learn from different modalities to enhance single-modality predictions. Earth Observation (EO) represents a quintessential…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Francisco Mena , Dino Ienco , Cassio F. Dantas , Roberto Interdonato , Andreas Dengel

Sparse Mixtures of Experts (SMoE) scales model capacity without significant increases in training and inference costs, but exhibits the following two issues: (1) Low expert activation, where only a small subset of experts are activated for…

Computation and Language · Computer Science 2024-04-24 Xun Wu , Shaohan Huang , Wenhui Wang , Furu Wei

Large Language Models (LLMs) are increasingly capable of generating complete applications from natural language instructions, creating new opportunities in science and education. In these domains, interactive scientific demonstrations are…

Software Engineering · Computer Science 2026-05-21 Qiaosheng Chen , Yang Liu , Lei Li , Kai Chen , Qipeng Guo , Gong Cheng , Fei Yuan

The emerging trend of advancing generalist artificial intelligence, such as GPTv4 and Gemini, has reshaped the landscape of research (academia and industry) in machine learning and many other research areas. However, domain-specific…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Xiaosong Wang , Xiaofan Zhang , Guotai Wang , Junjun He , Zhongyu Li , Wentao Zhu , Yi Guo , Qi Dou , Xiaoxiao Li , Dequan Wang , Liang Hong , Qicheng Lao , Tong Ruan , Yukun Zhou , Yixue Li , Jie Zhao , Kang Li , Xin Sun , Lifeng Zhu , Shaoting Zhang

Sparse Mixture of Experts (SMoE) has become the key to unlocking unparalleled scalability in deep learning. SMoE has the potential to exponentially increase parameter count while maintaining the efficiency of the model by only activating a…

Machine Learning · Computer Science 2024-10-21 Rachel S. Y. Teo , Tan M. Nguyen

The rapid advancement of remote sensing foundation models, particularly vision and multimodal models, has significantly enhanced the capabilities of intelligent geospatial data interpretation. These models combine various data modalities,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Ziyue Huang , Hongxi Yan , Qiqi Zhan , Shuai Yang , Mingming Zhang , Chenkai Zhang , YiMing Lei , Zeming Liu , Qingjie Liu , Yunhong Wang

We present Brain Harmony (BrainHarmonix), the first multimodal brain foundation model that unifies structural morphology and functional dynamics into compact 1D token representations. The model was pretrained on two of the largest…

Mixture of Experts (MoE) models enhance neural network scalability by dynamically selecting relevant experts per input token, enabling larger model sizes while maintaining manageable computation costs. However, efficient training of…

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