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Segmentation is vital for ophthalmology image analysis. But its various modal images hinder most of the existing segmentation algorithms applications, as they rely on training based on a large number of labels or hold weak generalization…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Zhongxi Qiu , Yan Hu , Heng Li , Jiang Liu

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Histopathology nuclei segmentation is crucial for quantitative tissue analysis and cancer diagnosis. Although existing segmentation methods have achieved strong performance, they are often computationally heavy and show limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Muhammad Hassan Maqsood , Yanming Zhu , Alfred Lam , Getamesay Dagnaw , Xuefei Yin , Alan Wee-Chung Liew

Segmentation of cellular structures in electron microscopy (EM) images is fundamental to analyzing the morphology of neurons and glial cells in the healthy and diseased brain tissue. Current neuronal segmentation applications are based on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Zewen Zhuo , Ilya Belevich , Ville Leinonen , Eija Jokitalo , Tarja Malm , Alejandra Sierra , Jussi Tohka

The success of large language models has inspired the computer vision community to explore image segmentation foundation model that is able to zero/few-shot generalize through prompt engineering. Segment-Anything(SAM), among others, is the…

Computer Vision and Pattern Recognition · Computer Science 2024-04-11 Haojie Zhang , Yongyi Su , Xun Xu , Kui Jia

Melanoma segmentation in Whole Slide Images (WSIs) is useful for prognosis and the measurement of crucial prognostic factors such as Breslow depth and primary invasive tumor size. In this paper, we present a novel approach that uses the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Qingyuan Liu , Avideh Zakhor

Segmentation in medical imaging is a critical component for the diagnosis, monitoring, and treatment of various diseases and medical conditions. Presently, the medical segmentation landscape is dominated by numerous specialized deep…

Training segmentation models for medical images continues to be challenging due to the limited availability of data annotations. Segment Anything Model (SAM) is a foundation model that is intended to segment user-defined objects of interest…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Maciej A. Mazurowski , Haoyu Dong , Hanxue Gu , Jichen Yang , Nicholas Konz , Yixin Zhang

Segment Anything Model (SAM) demonstrates powerful zero-shot capabilities; however, its accuracy and robustness significantly decrease when applied to medical image segmentation. Existing methods address this issue through modality fusion,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Yiheng Zhong , Zihong Luo , Chengzhi Liu , Feilong Tang , Zelin Peng , Ming Hu , Yingzhen Hu , Jionglong Su , Zongyuan Ge , Imran Razzak

Image segmentation is a critical task in microscopy, essential for accurately analyzing and interpreting complex visual data. This task can be performed using custom models trained on domain-specific datasets, transfer learning from…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Kamyar Barakati , Utkarsh Pratiush , Sheryl L. Sanchez , Aditya Raghavan , Delia J. Milliron , Mahshid Ahmadi , Philip D. Rack , Sergei V. Kalinin

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

Segment anything model (SAM) has emerged as the leading approach for zero-shot learning in segmentation tasks, offering the advantage of avoiding pixel-wise annotations. It is particularly appealing in medical image segmentation, where the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-29 Ziyi Huang , Hongshan Liu , Haofeng Zhang , Xueshen Li , Haozhe Liu , Fuyong Xing , Andrew Laine , Elsa Angelini , Christine Hendon , Yu Gan

Accurate characterization of carbon nanotube morphologies in electron microscopy images is vital for exposure assessment and toxicological studies, yet current workflows rely on slow, subjective manual segmentation. This work presents a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Sanjay Pradeep , Chen Wang , Matthew M. Dahm , Jeff D. Eldredge , Candace S. J. Tsai

The recent Segment Anything Models (SAMs) have emerged as foundational visual models for general interactive segmentation. Despite demonstrating robust generalization abilities, they still suffer performance degradations in scenarios…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Yuan Yao , Qiushi Yang , Miaomiao Cui , Liefeng Bo

Fabric defect segmentation is integral to textile quality control. Despite this, the scarcity of high-quality annotated data and the diversity of fabric defects present significant challenges to the application of deep learning in this…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Zhewei Chen , Wai Keung Wong , Zuofeng Zhong , Jinpiao Liao , Ying Qu

Weakly supervised semantic segmentation (WSSS) aims to bypass the need for laborious pixel-level annotation by using only image-level annotation. Most existing methods rely on Class Activation Maps (CAM) to derive pixel-level pseudo-labels…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Tianle Chen , Zheda Mai , Ruiwen Li , Wei-lun Chao

High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Jacob Hanimann , Daniel Siegismund , Mario Wieser , Stephan Steigele

Cell image segmentation is usually implemented using fully supervised deep learning methods, which heavily rely on extensive annotated training data. Yet, due to the complexity of cell morphology and the requirement for specialized…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Yu Zhu , Qiang Yang , Li Xu

The Segment-Anything Model (SAM) is a vision foundation model for segmentation with a prompt-driven framework. SAM generates class-agnostic masks based on user-specified instance-referring prompts. However, adapting SAM for automated…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Hussni Mohd Zakir , Eric Tatt Wei Ho
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