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The convergence of statistical learning and molecular physics is transforming our approach to modeling biomolecular systems. Physics-informed machine learning (PIML) offers a systematic framework that integrates data-driven inference with…

Biomolecules · Quantitative Biology 2025-11-11 Aaryesh Deshpande

Large language models (LLMs) are trained on massive datasets that may include private or copyrighted content. Due to growing privacy and ownership concerns, data owners may request the removal of their data from trained models. Machine…

Machine Learning · Computer Science 2026-01-13 Zhihao Liu , Jian Lou , Yuke Hu , Xiaochen Li , Yitian Chen , Tailun Chen , Zhizhen Qin , Kui Ren , Zhan Qin

During design optimization, a smooth description of the geometry is important, especially for problems that are sensitive to the way interfaces are resolved, e.g., wave propagation or fluid-structure interaction. A levelset description of…

Computational Engineering, Finance, and Science · Computer Science 2021-12-28 Sanne J. van den Boom , Jian Zhang , Fred van Keulen , Alejandro M. Aragón

We present a novel approach that integrates unfitted finite element methods and neural networks to approximate partial differential equations on complex geometries. Easy-to-generate background meshes (e.g., a simple Cartesian mesh) that cut…

Numerical Analysis · Mathematics 2025-12-04 Wei Li , Alberto F. Martín , Santiago Badia

Self-evolving reasoning frameworks let LLMs improve their reasoning capabilities by iteratively generating and solving problems without external supervision, using verifiable rewards. Ideally, such systems are expected to explore a diverse…

Machine Learning · Computer Science 2026-03-17 Vaibhav Mishra

We present the application of a class of deep learning, known as Physics Informed Neural Networks (PINN), to learning and discovery in solid mechanics. We explain how to incorporate the momentum balance and constitutive relations into PINN,…

Machine Learning · Computer Science 2020-05-12 Ehsan Haghighat , Maziar Raissi , Adrian Moure , Hector Gomez , Ruben Juanes

A key challenge in e-learning environments like Intelligent Tutoring Systems (ITSs) is to induce effective pedagogical policies efficiently. While Deep Reinforcement Learning (DRL) often suffers from sample inefficiency and reward function…

Machine Learning · Computer Science 2024-06-05 Md Mirajul Islam , Xi Yang , John Hostetter , Adittya Soukarjya Saha , Min Chi

We present a neural network-based method for solving linear and nonlinear partial differential equations, by combining the ideas of extreme learning machines (ELM), domain decomposition and local neural networks. The field solution on each…

Numerical Analysis · Mathematics 2021-09-22 Suchuan Dong , Zongwei Li

Real-time simulation of elastic structures is essential in many applications, from computer-guided surgical interventions to interactive design in mechanical engineering. The Finite Element Method is often used as the numerical method of…

Machine Learning · Computer Science 2021-09-21 Alban Odot , Ryadh Haferssas , Stéphane Cotin

The peridynamic theory brings advantages in dealing with discontinuities, dynamic loading, and non-locality. The integro-differential formulation of peridynamics poses challenges to numerical solutions of complicated and practical problems.…

Numerical Analysis · Mathematics 2021-06-01 Xue Liang , Linjuan Wang , Jifeng Xu , Jianxiang Wang

The paper is concerned with the development of efficient and accurate solution procedures for the isogeometric boundary element method (BEM) when applied to problems that contain inclusions that have elastic properties different to the…

Numerical Analysis · Mathematics 2020-10-28 Gernot Beer , Eugenio Ruocco , Christian Duenser , Vincenzo Mallardo

Physics-informed neural networks (PINNs) are emerging as popular mesh-free solvers for partial differential equations (PDEs). Recent extensions decompose the domain, apply different PINNs to solve the problem in each subdomain, and stitch…

Machine Learning · Computer Science 2023-07-07 Shibo Li , Michael Penwarden , Yiming Xu , Conor Tillinghast , Akil Narayan , Robert M. Kirby , Shandian Zhe

In this work, we have applied physics-informed neural networks (PINN) for solving mesh deformation problems. We used the collocation PINN method to capture the new positions of the vertex nodes while preserving the connectivity information.…

Fluid Dynamics · Physics 2023-01-18 Atakan Aygun , Romit Maulik , Ali Karakus

Deep neural network approaches show promise in solving partial differential equations. However, unlike traditional numerical methods, they face challenges in enforcing essential boundary conditions. The widely adopted penalty-type methods,…

Numerical Analysis · Mathematics 2026-05-06 Haijun Yu , Shuo Zhang

This paper introduces EdgeProfiler, a fast profiling framework designed for evaluating lightweight Large Language Models (LLMs) on edge systems. While LLMs offer remarkable capabilities in natural language understanding and generation,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-18 Alyssa Pinnock , Shakya Jayakody , Kawsher A Roxy , Md Rubel Ahmed

Extreme learning machine (ELM) as an emerging branch of shallow networks has shown its excellent generalization and fast learning speed. However, for blended data, the robustness of ELM is weak because its weights and biases of hidden nodes…

Machine Learning · Computer Science 2014-09-24 Bo Han , Bo He , Mengmeng Ma , Tingting Sun , Tianhong Yan , Amaury Lendasse

Many important problems in science and engineering require solving the so-called parametric partial differential equations (PDEs), i.e., PDEs with different physical parameters, boundary conditions, shapes of computation domains, etc.…

Machine Learning · Computer Science 2022-11-22 Xiang Huang , Zhanhong Ye , Hongsheng Liu , Beiji Shi , Zidong Wang , Kang Yang , Yang Li , Bingya Weng , Min Wang , Haotian Chu , Fan Yu , Bei Hua , Lei Chen , Bin Dong

Coupled multiphysics simulations for high-dimensional, large-scale problems can be prohibitively expensive due to their computational demands. This article presents a novel framework integrating a deep operator network (DeepONet) with the…

Computational Engineering, Finance, and Science · Computer Science 2025-09-03 Fouad M. Amin , Diab W. Abueidda , Panos Pantidis , Mostafa E. Mobasher

In-context learning (ICL) is an astonishing emergent ability of large language models (LLMs). By presenting a prompt that includes multiple input-output pairs as examples and introducing a new query input, models can generate the…

Machine Learning · Computer Science 2023-10-06 Timothy Chu , Zhao Song , Chiwun Yang

Inspired by the masked language modeling (MLM) in natural language processing tasks, the masked image modeling (MIM) has been recognized as a strong self-supervised pre-training method in computer vision. However, the high random mask ratio…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Zhaowen Li , Yousong Zhu , Zhiyang Chen , Wei Li , Chaoyang Zhao , Rui Zhao , Ming Tang , Jinqiao Wang
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