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Plain radiography is the most common modality to assess the stage of osteoarthritis. Our aims were to assess the relationship of radiography-based bone density and texture between radiographs with minimal and clinical post-processing, and…

Medical Physics · Physics 2019-02-07 Jukka Hirvasniemi , Jaakko Niinimäki , Jérôme Thevenot , Simo Saarakkala

OBJECTIVES: Quantitative MRI techniques such as T2 and T1$\rho$ mapping are beneficial in evaluating cartilage and meniscus. We aimed to evaluate the MIXTURE (Multi-Interleaved X-prepared Turbo-Spin Echo with IntUitive RElaxometry)…

Correlating articular cartilage material properties to quantitative magnetic resonance imaging biomarkers is a powerful approach to biofidelic finite element models. However, subject-specific relationships between imaging biomarkers such as…

Image and Video Processing · Electrical Eng. & Systems 2025-11-17 Alexander A. Donabedian , Deva D. Chan

Owing to the invasiveness and low accuracy of other tests, including biopsy and ferritin levels, magnetic resonance imaging (T2 and T2*-MRI) has been considered the standard test for patients with thalassemia (THM). Regarding deep learning…

Image and Video Processing · Electrical Eng. & Systems 2023-05-18 Iraj Abedi , Maryam Zamanian , Hamidreza Bolhasani , Milad Jalilian

Objective: We evaluate a fully-automated femoral cartilage segmentation model for measuring T2 relaxation values and longitudinal changes using multi-echo spin echo (MESE) MRI. We have open sourced this model and corresponding…

Computer Vision and Pattern Recognition · Computer Science 2020-12-24 Kevin A. Thomas , Dominik Krzemiński , Łukasz Kidziński , Rohan Paul , Elka B. Rubin , Eni Halilaj , Marianne S. Black , Akshay Chaudhari , Garry E. Gold , Scott L. Delp

Quantifying muscle tissue properties is crucial for understanding pathophysiological changes occurring in skeletal muscle (SM). In particular, T2 relaxation and diffusion MRI (dMRI) are promising techniques. However, typical methods measure…

Objective(s): T$_2$* and susceptibility ($\chi$) MRI mapping provide complimentary measures of the haemodynamic environment in the placenta. The aims of this work were to use these simultaneously obtained measures to investigate the role of…

Skull-base meningiomas are often characterized by favorable long-term prognosis, yet their anatomical complexity and proximity to critical neurovascular structures make treatment selection challenging. Stereotactic radiosurgery with…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yin Lin , Elena De Martin , Giacomo Conte , Domenico Aquino , Cristiana Pedone , Alberto Redaelli , Riccardo Barbieri , Laura Fariselli , Simona Ferrante

T2 mapping in fetal brain MRI has the potential to improve characterization of the developing brain, especially at mid-field (0.55T), where T2 decay is slower. However, this is challenging as fetal MRI acquisition relies on multiple…

Multiexponential T2 (MET2) Relaxometry and Magnetization Transfer (MT) are among the most promising MRI-derived techniques for white matter (WM) characterization. Both techniques are shown to have histologically correlated sensitivity to…

Medical Physics · Physics 2019-03-26 Teresa Serradas Duarte , Noam Shemesh

Magnetic resonance imaging (MRI) offers superior soft tissue contrast and is widely used in biomedicine. However, conventional MRI is not quantitative, which presents a bottleneck in image analysis and digital healthcare. Typically,…

Recovering the T2 distribution from multi-echo T2 magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this…

The understanding of the material properties of the layered transition metal dichalcogenides (TMDs) is critical for their applications in structural composites. The data-driven machine learning (ML) based approaches are being developed in…

Classical radiomic features are designed to quantify image appearance and intensity patterns. Compared with end-to-end deep learning (DL) models trained for disease classification, radiomics pipelines with low-dimensional parametric…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Yaxi Chen , Simin Ni , Jingjing Zhang , Shaheer U. Saeed , Yipei Wang , Aleksandra Ivanova , Rikin Hargunani , Chaozong Liu , Jie Huang , Yipeng Hu

The purpose of this work is to develop a deep learning-based method for knee menisci segmentation in 3D ultrashort echo time (UTE) cones magnetic resonance (MR) imaging, and to automatically determine MR relaxation times, namely the T1,…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Michal Byra , Mei Wu , Xiaodong Zhang , Hyungseok Jang , Ya-Jun Ma , Eric Y Chang , Sameer Shah , Jiang Du

Objectives: The role of advanced diffusion-weighted imaging (DWI) in chronic liver disease (CLD) has not been fully studied. Chronic liver disease (CLD) is a progressive deterioration of liver functions, caused by one or more etiology. This…

Tissues and Organs · Quantitative Biology 2025-09-10 Jiqing Huang , Benjamin Leporq , Valérie Hervieu , Sophie Gaillard , Jerome Dumortier , Olivier Beuf , Hélène Ratiney

Knee osteoarthritis (OA) is very common progressive and degenerative musculoskeletal disease worldwide creates a heavy burden on patients with reduced quality of life and also on society due to financial impact. Therefore, any attempt to…

Image and Video Processing · Electrical Eng. & Systems 2020-05-26 Neslihan Bayramoglu , Miika T. Nieminen , Simo Saarakkala

Purpose: We developed an artificial neural network (ANN) combining radiomics with clinical and dosimetric features to predict the extent of body mass index (BMI) increase after surgery and proton therapy, with advantage of improved accuracy…

Medical Physics · Physics 2025-09-26 Wenjun Yang , Chia-Ho Hua , Tina Davis , Jinsoo Uh , Thomas E. Merchant

The importance of radiomics features for predicting patient outcome is now well-established. Early study of prognostic features can lead to a more efficient treatment personalisation. For this reason new radiomics features obtained through…

Image and Video Processing · Electrical Eng. & Systems 2020-12-24 Paul Desbordes , Diksha , Benoit Macq

Introduction: Quantitative MRI techniques such as T2 and T1\r{ho} mapping are beneficial in evaluating knee joint pathologies; however, long acquisition times limit their clinical adoption. MIXTURE (Multi-Interleaved X-prepared Turbo-Spin…

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