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Anomaly detection is an emerging approach in digital pathology for its ability to efficiently and effectively utilize data for disease diagnosis. While supervised learning approaches deliver high accuracy, they rely on extensively annotated…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Keunho Byeon , Jinsol Song , Anh Nguyen , Sangjeong Ahn , Sung Hak Lee , Jin Tae Kwak

We present a system for anomaly detection in histopathological images. In histology, normal samples are usually abundant, whereas anomalous (pathological) cases are scarce or not available. Under such settings, one-class classifiers trained…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Igor Zingman , Birgit Stierstorfer , Charlotte Lempp , Fabian Heinemann

Anomaly detection is the problem of recognizing abnormal inputs based on the seen examples of normal data. Despite recent advances of deep learning in recognizing image anomalies, these methods still prove incapable of handling complex…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Nina Shvetsova , Bart Bakker , Irina Fedulova , Heinrich Schulz , Dmitry V. Dylov

Detection of visual anomalies refers to the problem of finding patterns in different imaging data that do not conform to the expected visual appearance and is a widely studied problem in different domains. Due to the nature of anomaly…

Image and Video Processing · Electrical Eng. & Systems 2021-04-29 Dejan Stepec , Danijel Skocaj

Anomaly detection consists in identifying, within a dataset, those samples that significantly differ from the majority of the data, representing the normal class. It has many practical applications, e.g. ranging from defective product…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Pankaj Mishra , Claudio Piciarelli , Gian Luca Foresti

Pathological brain appearances may be so heterogeneous as to be intelligible only as anomalies, defined by their deviation from normality rather than any specific pathological characteristic. Amongst the hardest tasks in medical imaging,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Walter Hugo Lopez Pinaya , Petru-Daniel Tudosiu , Robert Gray , Geraint Rees , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

Knowledge-augmented learning enables the combination of knowledge-based and data-driven approaches. For anomaly detection and diagnosis, understandability is typically an important factor, especially in high-risk areas. Therefore,…

Machine Learning · Computer Science 2024-12-03 Martin Atzmueller , Tim Bohne , Patricia Windler

The increasing digitization of medical imaging enables machine learning based improvements in detecting, visualizing and segmenting lesions, easing the workload for medical experts. However, supervised machine learning requires reliable…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Maximilian E. Tschuchnig , Michael Gadermayr

Recent advancements in large-scale visual-language pre-trained models have led to significant progress in zero-/few-shot anomaly detection within natural image domains. However, the substantial domain divergence between natural and medical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Chaoqin Huang , Aofan Jiang , Jinghao Feng , Ya Zhang , Xinchao Wang , Yanfeng Wang

Image anomaly detection problems aim to determine whether an image is abnormal, and to detect anomalous areas. These methods are actively used in various fields such as manufacturing, medical care, and intelligent information.…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yunseung Lee , Pilsung Kang

Anomaly detection is vital in various industrial scenarios, including the identification of unusual patterns in production lines and the detection of manufacturing defects for quality control. Existing techniques tend to be specialized in…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Xiaohao Xu , Yunkang Cao , Huaxin Zhang , Nong Sang , Xiaonan Huang

Image anomaly detection consists in finding images with anomalous, unusual patterns with respect to a set of normal data. Anomaly detection can be applied to several fields and has numerous practical applications, e.g. in industrial…

Computer Vision and Pattern Recognition · Computer Science 2019-09-09 Claudio Piciarelli , Pankaj Mishra , Gian Luca Foresti

Data-driven machine learning has made significant strides in medical image analysis. However, most existing methods are tailored to specific modalities and assume a particular resolution (often isotropic). This limits their generalizability…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Peirong Liu , Ana Lawry Aguila , Juan E. Iglesias

Zero-shot anomaly detection aims to identify defects in unseen categories without target-specific training. Existing methods usually apply the same feature transformation to all samples, treating normal and anomalous data uniformly despite…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Muhammad Aqeel , Maham Nazir , Uzair Khan , Marco Cristani , Francesco Setti

Machine learning (ML) algorithms are optimized for the distribution represented by the training data. For outlier data, they often deliver predictions with equal confidence, even though these should not be trusted. In order to deploy…

Image and Video Processing · Electrical Eng. & Systems 2021-03-17 Milda Pocevičiūtė , Gabriel Eilertsen , Claes Lundström

Anomalies can be defined as any non-random structure which deviates from normality. Anomaly detection methods reported in the literature are numerous and diverse, as what is considered anomalous usually varies depending on particular…

Computer Vision and Pattern Recognition · Computer Science 2021-10-07 Matias Tailanian , Pablo Musé , Álvaro Pardo

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias

Anomaly detection is to recognize samples that differ in some respect from the training observations. These samples which do not conform to the distribution of normal data are called outliers or anomalies. In real-world anomaly detection…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Vahid Reza Khazaie , Anthony Wong , Yalda Mohsenzadeh

Pathological anomalies exhibit diverse appearances in medical imaging, making it difficult to collect and annotate a representative amount of data required to train deep learning models in a supervised setting. Therefore, in this work, we…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Mariana-Iuliana Georgescu

Anomaly detection in medical images refers to the identification of abnormal images with only normal images in the training set. Most existing methods solve this problem with a self-reconstruction framework, which tends to learn an identity…

Image and Video Processing · Electrical Eng. & Systems 2021-10-06 Kang Zhou , Jing Li , Weixin Luo , Zhengxin Li , Jianlong Yang , Huazhu Fu , Jun Cheng , Jiang Liu , Shenghua Gao
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