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Applying machine learning to real-world medical data, e.g. from hospital archives, has the potential to revolutionize disease detection in brain images. However, detecting pathology in such heterogeneous cohorts is a difficult challenge.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Ana Lawry Aguila , Ayodeji Ijishakin , Juan Eugenio Iglesias , Tomomi Takenaga , Yukihiro Nomura , Takeharu Yoshikawa , Osamu Abe , Shouhei Hanaoka

Anomaly detection is crucial to ensure the security of cyber-physical systems (CPS). However, due to the increasing complexity of CPSs and more sophisticated attacks, conventional anomaly detection methods, which face the growing volume of…

Cryptography and Security · Computer Science 2021-01-20 Yuan Luo , Ya Xiao , Long Cheng , Guojun Peng , Danfeng Daphne Yao

Anomaly detection is being regarded as an unsupervised learning task as anomalies stem from adversarial or unlikely events with unknown distributions. However, the predictive performance of purely unsupervised anomaly detection often fails…

Machine Learning · Computer Science 2014-01-27 Nico Goernitz , Marius Micha Kloft , Konrad Rieck , Ulf Brefeld

Artificial Intelligence (AI) based image analysis has an immense potential to support diagnostic histopathology, including cancer diagnostics. However, developing supervised AI methods requires large-scale annotated datasets. A potentially…

Anomalous diffusion occurs at very different scales in nature, from atomic systems to motions in cell organelles, biological tissues or ecology, and also in artificial materials, such as cement. Being able to accurately measure the…

Machine Learning · Computer Science 2021-08-09 Òscar Garibo i Orts , Miguel A. Garcia-March , J. Alberto Conejero

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Recent studies give more attention to the anomaly detection (AD) methods that can leverage a handful of labeled anomalies along with abundant unlabeled data. These existing anomaly-informed AD methods rely on manually predefined score…

Machine Learning · Computer Science 2023-06-27 Minqi Jiang , Songqiao Han , Hailiang Huang

Training in unsupervised time series anomaly detection is constantly plagued by the discrimination between harmful `anomaly contaminations' and beneficial `hard normal samples'. These two samples exhibit analogous loss behavior that…

Machine Learning · Computer Science 2026-03-17 Ruyi Zhang , Hongzuo Xu , Songlei Jian , Yusong Tan , Haifang Zhou , Rulin Xu

The essence of unsupervised anomaly detection is to learn the compact distribution of normal samples and detect outliers as anomalies in testing. Meanwhile, the anomalies in real-world are usually subtle and fine-grained in a…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Ye Zheng , Xiang Wang , Rui Deng , Tianpeng Bao , Rui Zhao , Liwei Wu

In this work we propose a one-class self-supervised method for anomaly segmentation in images that benefits both from a modern machine learning approach and a more classic statistical detection theory. The method consists of four phases.…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Matías Tailanian , Álvaro Pardo , Pablo Musé

Anomaly detection plays a vital role in industrial manufacturing. Due to the scarcity of real defect images, unsupervised approaches that rely solely on normal images have been extensively studied. Recently, diffusion-based generative…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Sungho Kang , Hyunkyu Park , Yeonho Lee , Hanbyul Lee , Mijoo Jeong , YeongHyeon Park , Injae Lee , Juneho Yi

Contrastive Analysis (CA) detects anomalies by contrasting patterns unique to a target group (e.g., unhealthy subjects) from those in a background group (e.g., healthy subjects). In the context of brain MRIs, existing CA approaches rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Cristiano Patrício , Carlo Alberto Barbano , Attilio Fiandrotti , Riccardo Renzulli , Marco Grangetto , Luis F. Teixeira , João C. Neves

When recording the movement of individual animals, cells or molecules one will often observe changes in their diffusive behaviour at certain points in time along their trajectory. In order to capture the different diffusive modes assembled…

Statistical Mechanics · Physics 2024-10-21 Henrik Seckler , Ralf Metzler

Anomalies are intuitively easy for human experts to understand, but they are hard to define mathematically. Therefore, in order to have performance guarantees in unsupervised anomaly detection, priors need to be assumed on what the…

Machine Learning · Statistics 2020-04-08 Tiago Pimentel , Marianne Monteiro , Adriano Veloso , Nivio Ziviani

Unsupervised anomaly segmentation aims to detect patterns that are distinct from any patterns processed during training, commonly called abnormal or out-of-distribution patterns, without providing any associated manual segmentations. Since…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Ziyun Liang , Harry Anthony , Felix Wagner , Konstantinos Kamnitsas

Anomaly detection (AD) is a crucial machine learning task that aims to learn patterns from a set of normal training samples to identify abnormal samples in test data. Most existing AD studies assume that the training and test data are drawn…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Tri Cao , Jiawen Zhu , Guansong Pang

Pathology detection and delineation enables the automatic interpretation of medical scans such as chest X-rays while providing a high level of explainability to support radiologists in making informed decisions. However, annotating…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Philip Müller , Felix Meissen , Johannes Brandt , Georgios Kaissis , Daniel Rueckert

Anomaly detection and localization in medical images is a challenging task, especially when the anomaly exhibits a change of existing structures, e.g., brain atrophy or changes in the pleural space due to pleural effusions. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-29 Julia Wolleb , Robin Sandkühler , Philippe C. Cattin

Analyzing the distribution shift of data is a growing research direction in nowadays Machine Learning (ML), leading to emerging new benchmarks that focus on providing a suitable scenario for studying the generalization properties of ML…

Machine Learning · Computer Science 2023-04-04 Marius Dragoi , Elena Burceanu , Emanuela Haller , Andrei Manolache , Florin Brad

Unsupervised graph-level anomaly detection (UGAD) has attracted increasing interest due to its widespread application. In recent studies, knowledge distillation-based methods have been widely used in unsupervised anomaly detection to…

Machine Learning · Computer Science 2024-07-02 Rui Cao , Shijie Xue , Jindong Li , Qi Wang , Yi Chang
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