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Accurate fine-grained segmentation of the renal vasculature is critical for nephrological analysis, yet it faces challenges due to diverse and insufficiently annotated images. Existing methods struggle to accurately segment intricate…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Yitian Long , Zhongze Wu , Xiu Su , Lining Yu , Ruining Deng , Haichun Yang , Yuankai Huo

Feature selection is essential in the analysis of molecular systems and many other fields, but several uncertainties remain: What is the optimal number of features for a simplified, interpretable model that retains essential information?…

Machine Learning · Computer Science 2025-01-22 Romina Wild , Felix Wodaczek , Vittorio Del Tatto , Bingqing Cheng , Alessandro Laio

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam

For automated assessment of knee MRI scans, both accuracy and interpretability are essential for clinical use and adoption. Traditional radiomics rely on predefined features chosen at the population level; while more interpretable, they are…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Yaxi Chen , Simin Ni , Shuai Li , Shaheer U. Saeed , Aleksandra Ivanova , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

Thyroid nodule segmentation in ultrasound images is crucial for accurate diagnosis and treatment planning. However, existing methods face challenges in segmentation accuracy, interpretability, and generalization, which hinder their…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Xinjie Sun , Boxiong Wei , Yalong Jiang , Liquan Mao , Qi Zhao

Cell instance segmentation in cytology images has significant importance for biology analysis and cancer screening, while remains challenging due to 1) the extensive overlapping translucent cell clusters that cause the ambiguous boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Hao Jiang , Rushan Zhang , Yanning Zhou , Yumeng Wang , Hao Chen

Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imaging (MRI), provides a noninvasive means of observing the aging…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Jingru Fu , Antonios Tzortzakakis , José Barroso , Eric Westman , Daniel Ferreira , Rodrigo Moreno

The objective of this study was to develop an automated pipeline that enhances thyroid disease classification using thyroid scintigraphy images, aiming to decrease assessment time and increase diagnostic accuracy. Anterior thyroid…

Weakly supervised 3D instance segmentation is essential for 3D scene understanding, especially as the growing scale of data and high annotation costs associated with fully supervised approaches. Existing methods primarily rely on two forms…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Xuexun Liu , Xiaoxu Xu , Qiudan Zhang , Lin Ma , Xu Wang

Nonlinear registration of 2D histological sections with corresponding slices of MRI data is a critical step of 3D histology reconstruction. This task is difficult due to the large differences in image contrast and resolution, as well as the…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Juan Eugenio Iglesias , Marc Modat , Loic Peter , Allison Stevens , Roberto Annunziata , Tom Vercauteren , Ed Lein , Bruce Fischl , Sebastien Ourselin

Nuclei instance segmentation is an essential task in pathology image analysis, serving as the foundation for many downstream applications. The release of several public datasets has significantly advanced research in this area, yet many…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Jin Tae Kwak

Robotic-assisted tracheal intubation requires the robot to distinguish anatomical features like an experienced physician using deep-learning techniques. However, real datasets of oropharyngeal organs are limited due to patient privacy…

Image and Video Processing · Electrical Eng. & Systems 2023-07-29 Guankun Wang , Tian-Ao Ren , Jiewen Lai , Long Bai , Hongliang Ren

The quantification of biomarkers on immunohistochemistry breast cancer images is essential for defining appropriate therapy for breast cancer patients, as well as for extracting relevant information on disease prognosis. This is an arduous…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Blanca Maria Priego-Torresa , Barbara Lobato-Delgado , Lidia Atienza-Cuevas , Daniel Sanchez-Morillo

Instance segmentation of biological images is essential for studying object behaviors and properties. The challenges, such as clustering, occlusion, and adhesion problems of the objects, make instance segmentation a non-trivial task.…

Computer Vision and Pattern Recognition · Computer Science 2019-11-22 Jingru Yi , Hui Tang , Pengxiang Wu , Bo Liu , Daniel J. Hoeppner , Dimitris N. Metaxas , Lianyi Han , Wei Fan

Large-scale semantic segmentation networks often achieve high performance, while their application can be challenging when faced with limited sample sizes and computational resources. In scenarios with restricted network size and…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Wentao Wang , Xili Wang

Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced…

Generally, microscopy image analysis in biology relies on the segmentation of individual nuclei, using a dedicated stained image, to identify individual cells. However stained nuclei have drawbacks like the need for sample preparation, and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Gendarme Mathieu , Lambert Annika M. , El Debs Bachir

Multimodal magnetic resonance imaging (MRI) is crucial for brain tumor segmentation, with many methods leveraging its four key modalities to capture complementary information for effective sub-region analysis. However, the absence of…

Artificial Intelligence · Computer Science 2026-05-19 Sha Tao , Jiao Pan , Yu Guo , Chao Yao