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Functional connections in the brain are frequently represented by weighted networks, with nodes representing locations in the brain, and edges representing the strength of connectivity between these locations. One challenge in analyzing…

Applications · Statistics 2022-09-28 Yura Kim , Daniel Kessler , Elizaveta Levina

Accurate diagnosis of Parkinson's disease (PD) from MRI remains challenging due to symptom variability and pathological heterogeneity. Most existing methods rely on conventional magnitude-based MRI modalities, such as T1-weighted images…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Rui Jin , Chen Chen , Yin Liu , Hongfu Sun , Min Zeng , Min Li , Yang Gao

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

Graph Neural Networks (GNN) have recently gained popularity in the forecasting domain due to their ability to model complex spatial and temporal patterns in tasks such as traffic forecasting and region-based demand forecasting. Most of…

Machine Learning · Computer Science 2023-12-08 Abishek Sriramulu , Nicolas Fourrier , Christoph Bergmeir

In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to find meaningful temporal latent representations of an…

Modeling clinical time-series data is hampered by the challenge of capturing latent, time-varying dependencies among features. State-of-the-art approaches often rely on black-box mechanisms or simple aggregation, failing to explicitly model…

Machine Learning · Computer Science 2026-01-21 Yubo Li , Rema Padman

Parameter estimation in structural dynamics generally involves inferring the values of physical, geometric, or even customized parameters based on first principles or expert knowledge, which is challenging for complex structural systems. In…

Computational Engineering, Finance, and Science · Computer Science 2025-04-08 Mingyuan Zhou , Haoze Song , Wenjing Ye , Wei Wang , Zhilu Lai

Trajectory prediction is fundamental to various intelligent technologies, such as autonomous driving and robotics. The motion prediction of pedestrians and vehicles helps emergency braking, reduces collisions, and improves traffic safety.…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Yao Liu , Binghao Li , Xianzhi Wang , Claude Sammut , Lina Yao

Morphological development into evolutionary patterns under structural instability is ubiquitous in living systems and often of vital importance for engineering structures. Here we propose a data-driven approach to understand and predict…

Pattern Formation and Solitons · Physics 2024-07-23 Yingjie Zhao , Zhiping Xu

Robust forecasting of the future anatomical changes inflicted by an ongoing disease is an extremely challenging task that is out of grasp even for experienced healthcare professionals. Such a capability, however, is of great importance…

Computer Vision and Pattern Recognition · Computer Science 2022-11-09 Dmitrii Lachinov , Arunava Chakravarty , Christoph Grechenig , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the death of dopaminergic neurons, leading to various movement disorder symptoms. Early diagnosis of PD is crucial to prevent adverse effects, yet…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Nabil Daiyan , Md Rakibul Haque

Time series prediction is an important problem in machine learning. Previous methods for time series prediction did not involve additional information. With a lot of dynamic knowledge graphs available, we can use this additional information…

Machine Learning · Computer Science 2020-07-14 Sankalp Garg , Navodita Sharma , Woojeong Jin , Xiang Ren

Electronic Health Records (EHR) systematically organize patient health data through standardized medical codes, serving as a comprehensive and invaluable source for predictive modeling. Graph neural networks (GNNs) have demonstrated…

Machine Learning · Computer Science 2025-08-29 Haiyan Wang , Ye Yuan

Accurate and real-time traffic forecasting plays an important role in the Intelligent Traffic System and is of great significance for urban traffic planning, traffic management, and traffic control. However, traffic forecasting has always…

Machine Learning · Computer Science 2019-08-13 Ling Zhao , Yujiao Song , Chao Zhang , Yu Liu , Pu Wang , Tao Lin , Min Deng , Haifeng Li

Computational models of neurodegeneration aim to emulate the evolving pattern of pathology in the brain during neurodegenerative disease, such as Alzheimer's disease. Previous studies have made specific choices on the mechanisms of…

Quantitative Methods · Quantitative Biology 2023-08-11 Tiantian He , Elinor Thompson , Anna Schroder , Neil P. Oxtoby , Ahmed Abdulaal , Frederik Barkhof , Daniel C. Alexander

Temporality, a crucial characteristic in the formation of social relationships, was used to quantify the long-term time effects of networks for link prediction models, ignoring the heterogeneity of time effects on different time scales. In…

Social and Information Networks · Computer Science 2024-06-17 Yueran Duan , Mateusz Nurek , Qing Guan , Radosław Michalski , Petter Holme

At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…

Machine Learning · Computer Science 2020-05-07 Afra Nawar , Farhan Rahman , Narayanan Krishnamurthi , Anirudh Som , Pavan Turaga

The integration and transmission of information in the brain are dependent on the interplay between structural and dynamical properties. Implicit in any pursuit aimed at understanding neural dynamics from appropriate sets of mathematically…

Neurons and Cognition · Quantitative Biology 2020-06-30 Joshua M. Roldan , Sebastian Pardo G. , Vivek Kurien George , Gabriel A. Silva

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

Quantitative Methods · Quantitative Biology 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

Clinical risk prediction using electronic health records (EHRs) is vital to facilitate timely interventions and clinical decision support. However, modeling heterogeneous and irregular temporal EHR data presents significant challenges. We…

Machine Learning · Computer Science 2025-11-04 Kun-Wei Lin , Yu-Chen Kuo , Hsin-Yao Wang , Yi-Ju Tseng