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Objectives: The present study evaluated the impact of a commercially available explainable AI algorithm in augmenting the ability of clinicians to identify lung cancer on chest X-rays (CXR). Design: This retrospective study evaluated the…
To address the limitations of Large Language Models (LLMs) in the International Classification of Diseases (ICD) coding task, where they often produce inaccurate and incomplete prediction results due to the high-dimensional and skewed…
This paper presents an innovative large language model (LLM) agent framework for enhancing diagnostic accuracy in simulated clinical environments using the AgentClinic benchmark. The proposed automatic correction enables doctor agents to…
Alignment of Large Language models (LLMs) is crucial for safe and trustworthy deployment in applications. Reinforcement learning from human feedback (RLHF) has emerged as an effective technique to align LLMs to human preferences and broader…
Clinical trials are critical for advancing medical treatments but remain prohibitively expensive and time-consuming. Accurate prediction of clinical trial outcomes can significantly reduce research and development costs and accelerate drug…
The field of lung nodule detection and cancer prediction has been rapidly developing with the support of large public data archives. Previous studies have largely focused on cross-sectional (single) CT data. Herein, we consider longitudinal…
As large language models (LLMs) are increasingly integrated into multi-agent and human-AI systems, understanding their awareness of both self-context and conversational partners is essential for ensuring reliable performance and robust…
Fulfilling the promise of precision medicine requires accurately and precisely classifying disease states. For cancer, this includes prediction of survival time from a surfeit of covariates. Such data presents an opportunity for improved…
As large language models (LLMs) become more specialized, we envision a future where millions of expert LLMs exist, each trained on proprietary data and excelling in specific domains. In such a system, answering a query requires selecting a…
Deriving personalized insights from popular wearable trackers requires complex numerical reasoning that challenges standard LLMs, necessitating tool-based approaches like code generation. Large language model (LLM) agents present a…
A burgeoning area within reinforcement learning (RL) is the design of sequential decision-making agents centered around large language models (LLMs). While autonomous decision-making agents powered by modern LLMs could facilitate numerous…
We design an efficient algorithm that outputs tests for identifying predominantly homogeneous subcohorts of patients from large in-homogeneous datasets. Our theoretical contribution is a rounding technique, similar to that of Goemans and…
Lung cancer remains one of the leading causes of morbidity and mortality worldwide, making early diagnosis critical for improving therapeutic outcomes and patient prognosis. Computer-aided diagnosis systems, which analyze computed…
Large language model (LLM) agents extend generative models with reasoning, tool use, and persistent memory, thereby enabling the automation of complex tasks. In healthcare, such systems could support documentation, care coordination, and…
Recently, Diffusion Large Language Models (dLLMs) have demonstrated unique efficiency advantages, enabled by their inherently parallel decoding mechanism and flexible generation paradigm. Meanwhile, despite the rapid advancement of Search…
Risk-adapted breast cancer screening requires robust models that leverage longitudinal imaging data. Most current deep learning models use single or limited prior mammograms and lack adaptation for real-world settings marked by imbalanced…
Retrieval-Augmented Large Language Models (LLMs), which incorporate the non-parametric knowledge from external knowledge bases into LLMs, have emerged as a promising approach to enhancing response accuracy in several tasks, such as…
Large Language Models (LLMs) have demonstrated exceptional capabilities, yet selecting the most reliable response from multiple LLMs remains a challenge, particularly in resource-constrained settings. Existing approaches often depend on…
Can Large Language Models (LLMs) accurately predict election outcomes? While LLMs have demonstrated impressive performance in various domains, including healthcare, legal analysis, and creative tasks, their ability to forecast elections…
Large Language Models (LLMs) are increasingly capable but often require significant guidance or extensive interaction history to perform effectively in complex, interactive environments. Existing methods may struggle with adapting to new…