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Medical image registration is a critical component of clinical imaging workflows, enabling accurate longitudinal assessment, multi-modal data fusion, and image-guided interventions. Intensity-based approaches often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Eytan Kats , Mattias P. Heinrich

Existing medical image registration algorithms rely on either dataset specific training or local texture-based features to align images. The former cannot be reliably implemented without large modality-specific training datasets, while the…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Xinrui Song , Xuanang Xu , Pingkun Yan

This paper aims to create a deep learning framework that can estimate the deformation vector field (DVF) for directly registering abdominal MRI-CT images. The proposed method assumed a diffeomorphic deformation. By using topology-preserved…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Yang Lei , Luke A. Matkovic , Justin Roper , Tonghe Wang , Jun Zhou , Beth Ghavidel , Mark McDonald , Pretesh Patel , Xiaofeng Yang

We propose a deformable registration algorithm based on unsupervised learning of a low-dimensional probabilistic parameterization of deformations. We model registration in a probabilistic and generative fashion, by applying a conditional…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Julian Krebs , Tommaso Mansi , Boris Mailhé , Nicholas Ayache , Hervé Delingette

Adnexal mass evaluation via ultrasound is a challenging clinical task, often hindered by subjective interpretation and significant inter-observer variability. While automated segmentation is a foundational step for quantitative risk…

Registration is a fundamental task in medical robotics and is often a crucial step for many downstream tasks such as motion analysis, intra-operative tracking and image segmentation. Popular registration methods such as ANTs and NiftyReg…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Wentao Zhu , Yufang Huang , Daguang Xu , Zhen Qian , Wei Fan , Xiaohui Xie

Diffusion tensor cardiac magnetic resonance (DT-CMR) is a method capable of providing non-invasive measurements of myocardial microstructure. Image registration is essential to correct image shifts due to intra and inter breath-hold motion…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Fanwen Wang , Pedro F. Ferreira , Yinzhe Wu , Camila Munoz , Ke Wen , Yaqing Luo , Jiahao Huang , Dudley J. Pennell , Andrew D. Scott , Sonia Nielles-Vallespin , Guang Yang

Accurate tissue motion tracking is critical to ensure treatment outcome and safety in 2D-Cine MRI-guided radiotherapy. This is typically achieved by registration of sequential images, but existing methods often face challenges with large…

Image and Video Processing · Electrical Eng. & Systems 2025-08-15 Soorena Salari , Catherine Spino , Laurie-Anne Pharand , Fabienne Lathuiliere , Hassan Rivaz , Silvain Beriault , Yiming Xiao

Adapting foundation models to medical segmentation typically requires either backbone fine-tuning or high-capacity task-specific decoders, both of which are difficult to fit reliably when annotations are scarce. We show that frozen DINOv3…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Wei Jiang , Feng Liu , Nan Ye , Hongfu Sun

Diffeomorphic deformable image registration ensures smooth invertible transformations across inspiratory and expiratory chest CT scans. Yet, in practice, deep learning-based diffeomorphic methods struggle to capture large deformations…

Image and Video Processing · Electrical Eng. & Systems 2024-11-13 Muhammad F. A. Chaudhary , Stephanie M. Aguilera , Arie Nakhmani , Joseph M. Reinhardt , Surya P. Bhatt , Sandeep Bodduluri

Diffeomorphic image registration (DIR) is a fundamental task in 3D medical image analysis that seeks topology-preserving deformations between image pairs. To ensure diffeomorphism, a common approach is to model the deformation field as the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Mohammadjavad Matinkia , Nilanjan Ray

This study proposes an end-to-end unsupervised diffeomorphic deformable registration framework based on moving mesh parameterization. Using this parameterization, a deformation field can be modeled with its transformation Jacobian…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Ameneh Sheikhjafari , Deepa Krishnaswamy , Michelle Noga , Nilanjan Ray , Kumaradevan Punithakumar

Carotid intima-media thickness (CIMT) measured from B-mode ultrasound is an established vascular biomarker for atherosclerosis and cardiovascular risk stratification. Although a wide range of computerized methods have been proposed for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Zhenpeng Zhang , Jinwei Lu , Yurui Dong , Bo Yuan

While deep learning has achieved significant advances in accuracy for medical image segmentation, its benefits for deformable image registration have so far remained limited to reduced computation times. Previous work has either focused on…

Computer Vision and Pattern Recognition · Computer Science 2018-12-06 Alessa Hering , Sven Kuckertz , Stefan Heldmann , Mattias Heinrich

Medical image registration is a challenging task involving the estimation of spatial transformations to establish anatomical correspondence between pairs or groups of images. Recently, deep learning-based image registration methods have…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Xiang Chen , Yan Xia , Nishant Ravikumar , Alejandro F Frangi

Diffeomorphic image registration, offering smooth transformation and topology preservation, is required in many medical image analysis tasks.Traditional methods impose certain modeling constraints on the space of admissible transformations…

Computer Vision and Pattern Recognition · Computer Science 2022-11-03 Kun Han , Shanlin sun , Xiangyi Yan , Chenyu You , Hao Tang , Junayed Naushad , Haoyu Ma , Deying Kong , Xiaohui Xie

We present a novel computational approach to fast and memory-efficient deformable image registration. In the variational registration model, the computation of the objective function derivatives is the computationally most expensive…

Computer Vision and Pattern Recognition · Computer Science 2018-04-30 Lars König , Jan Rühaak , Alexander Derksen , Jan Lellmann

State-of-the-art vessel segmentation methods typically require large-scale annotated datasets and suffer from severe performance degradation under domain shifts. In clinical practice, however, acquiring extensive annotations for every new…

Image and Video Processing · Electrical Eng. & Systems 2026-03-02 Kirato Yoshihara , Yohei Sugawara , Yuta Tokuoka , Lihang Hong

Foundation vision encoders such as CLIP and DINOv2, trained on web-scale data, exhibit strong transfer performance across tasks and datasets. However, medical imaging foundation models remain constrained by smaller datasets, limiting our…

Existing foundation models (FMs) in the medical domain often require extensive fine-tuning or rely on training resource-intensive decoders, while many existing encoders are pretrained with objectives biased toward specific tasks. This…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Tim Veenboer , George Yiasemis , Eric Marcus , Vivien Van Veldhuizen , Cees G. M. Snoek , Jonas Teuwen , Kevin B. W. Groot Lipman
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