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Recent advanced LLM-powered agent systems have exhibited their remarkable capabilities in tackling complex, long-horizon tasks. Nevertheless, they still suffer from inherent limitations in resource efficiency, context management, and…

Recent research shows that LLM Agents can generate ``believable'' human behaviors via prompt-only methods, and such agents have been increasingly adopted in downstream applications. However, existing evaluation of these agents only focuses…

Computation and Language · Computer Science 2026-04-30 Yuxuan Lu , Jing Huang , Yan Han , Bingsheng Yao , Sisong Bei , Jiri Gesi , Yaochen Xie , Yisi Sang , Zheshen , Wang , Qi He , Dakuo Wang

We propose a simulation-optimization-based methodology to improve the way that organ transplant offers are made to potential recipients. Our policy can be applied to all types of organs, is implemented starting at the local level, is…

Medical Physics · Physics 2022-12-01 Ignacio Erazo , David Goldsman , Pinar Keskinocak , Joel Sokol

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

Agent-based modeling (ABM) offers powerful insights into complex systems, but its practical utility has been limited by computational constraints and simplistic agent behaviors, especially when simulating large populations. Recent…

Multiagent Systems · Computer Science 2024-11-12 Ayush Chopra , Shashank Kumar , Nurullah Giray-Kuru , Ramesh Raskar , Arnau Quera-Bofarull

Agent-based modeling plays an essential role in gaining insights into biology, sociology, economics, and other fields. However, many existing agent-based simulation platforms are not suitable for large-scale studies due to the low…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-04-25 Lukas Breitwieser , Ahmad Hesam , Fons Rademakers , Juan Gómez Luna , Onur Mutlu

The integration of Artificial Intelligence (AI) with High-Performance Computing (HPC) is transforming scientific workflows from human-directed pipelines into adaptive systems capable of autonomous decision-making. Large language models…

We present M-Reason, a demonstration system for transparent, agent-based reasoning and evidence integration in the biomedical domain, with a focus on cancer research. M-Reason leverages recent advances in large language models (LLMs) and…

Artificial Intelligence · Computer Science 2025-10-08 Oskar Wysocki , Magdalena Wysocka , Mauricio Jacobo , Harriet Unsworth , André Freitas

Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…

Human-Computer Interaction · Computer Science 2025-12-30 Veronica Bossio Botero , Vijay Yadav , Jacob Ouyang , Anzar Abbas , Michelle Worthington

Recent advances in large language models (LLMs) have opened new avenues for applying multi-agent systems in very large-scale simulations. However, there remain several challenges when conducting multi-agent simulations with existing…

Multiagent Systems · Computer Science 2024-10-29 Xuchen Pan , Dawei Gao , Yuexiang Xie , Yushuo Chen , Zhewei Wei , Yaliang Li , Bolin Ding , Ji-Rong Wen , Jingren Zhou

A major challenge in developing robust and generalizable Human Activity Recognition (HAR) systems for smart homes is the lack of large and diverse labeled datasets. Variations in home layouts, sensor configurations, and individual behaviors…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Zikang Leng , Megha Thukral , Yaqi Liu , Hrudhai Rajasekhar , Shruthi K. Hiremath , Jiaman He , Thomas Plötz

Effective modeling of how human travelers learn and adjust their travel behavior from interacting with transportation systems is critical for system assessment and planning. However, this task is also difficult due to the complex cognition…

Artificial Intelligence · Computer Science 2025-11-04 Tianming Liu , Jirong Yang , Yafeng Yin , Manzi Li , Linghao Wang , Zheng Zhu

Agent-based simulators provide granular representations of complex intelligent systems by directly modelling the interactions of the system's constituent agents. Their high-fidelity nature enables hyper-local policy evaluation and testing…

Computer-using agents powered by Vision-Language Models (VLMs) have demonstrated human-like capabilities in operating digital environments like mobile platforms. While these agents hold great promise for advancing digital automation, their…

Doctor-patient consultations require multi-turn, context-aware communication tailored to diverse patient personas. Training or evaluating doctor LLMs in such settings requires realistic patient interaction systems. However, existing…

Artificial Intelligence · Computer Science 2025-10-30 Daeun Kyung , Hyunseung Chung , Seongsu Bae , Jiho Kim , Jae Ho Sohn , Taerim Kim , Soo Kyung Kim , Edward Choi

Recent advancements in large language models (LLMs) have led to the creation of intelligent agents capable of performing complex tasks. This paper introduces a novel LLM-based multimodal agent framework designed to operate smartphone…

Computer Vision and Pattern Recognition · Computer Science 2023-12-25 Chi Zhang , Zhao Yang , Jiaxuan Liu , Yucheng Han , Xin Chen , Zebiao Huang , Bin Fu , Gang Yu

Patient simulators are gaining traction in mental health training by providing scalable exposure to complex and sensitive patient interactions. Simulating depressed patients is particularly challenging, as safety constraints and high…

Computation and Language · Computer Science 2026-04-29 Nguyen Khoi Hoang , Shuhaib Mehri , Tse-An Hsu , Yi-Jyun Sun , Quynh Xuan Nguyen Truong , Khoa D Doan , Dilek Hakkani-Tür

In this paper, our objective is to develop a multi-agent financial system that incorporates simulated trading, a technique extensively utilized by financial professionals. While current LLM-based agent models demonstrate competitive…

Artificial Intelligence · Computer Science 2025-10-07 Xiangyu Li , Yawen Zeng , Xiaofen Xing , Jin Xu , Xiangmin Xu

Online health resources and large language models (LLMs) are increasingly used as a first point of contact for medical decision-making, yet their reliability in healthcare remains limited by low accuracy, lack of transparency, and…

Artificial Intelligence · Computer Science 2026-04-22 Yujia Liu , Sophia Yu , Hongyue Jin , Jessica Wen , Alexander Qian , Terrence Lee , Mattheus Ramsis , Gi Won Choi , Lianhui Qin , Xin Liu , Edward J. Wang

Open-sourced Large Language Models (LLMs) have achieved great success in various NLP tasks, however, they are still far inferior to API-based models when acting as agents. How to integrate agent ability into general LLMs becomes a crucial…

Computation and Language · Computer Science 2024-03-20 Zehui Chen , Kuikun Liu , Qiuchen Wang , Wenwei Zhang , Jiangning Liu , Dahua Lin , Kai Chen , Feng Zhao