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Detecting interaction effects among predictors on the response variable is a crucial step in various applications. In this paper, we first propose a simple method for sure screening interactions (SSI). Although its computation complexity is…
Predicting protein-protein interactions from sequences is an important goal of computational biology. Various sources of information can be used to this end. Starting from the sequences of two interacting protein families, one can use…
Motivation: The comparison of diverse genomic datasets is fundamental to understanding genome biology. Researchers must explore many large datasets of genome intervals (e.g., genes, sequence alignments) to place their experimental results…
Specific protein-protein interactions are crucial in the cell, both to ensure the formation and stability of multi-protein complexes, and to enable signal transduction in various pathways. Functional interactions between proteins result in…
As research into community finding in social networks progresses, there is a need for algorithms capable of detecting overlapping community structure. Many algorithms have been proposed in recent years that are capable of assigning each…
State-of-the-art animal classification models like SpeciesNet provide predictions across thousands of species but use conservative rollup strategies, resulting in many animals labeled at high taxonomic levels rather than species. We present…
Social networks facilitate the social space where actors or the users have ties among them. The ties and their patterns are based on their life styles and communication. Similarly, in online social media networks like Facebook, Twitter,…
In an effort to effectively model observed patterns in the spatial configuration of individuals of multiple species in nature, we introduce the saturated pairwise interaction Gibbs point process. Its main strength lies in its ability to…
Calculation of near-neighbor interactions among high dimensional, irregularly distributed data points is a fundamental task to many graph-based or kernel-based machine learning algorithms and applications. Such calculations, involving…
We have created a large database of similarity information between sub-regions of Hubble Space Telescope images. These data can be used to assess the accuracy of image search algorithms based on computer vision methods. The images were…
Knowledge of the association information between the attributes in a data set provides insight into the underlying structure of the data and explains the relationships (independence, synergy, redundancy) between the attributes and class (if…
Uncovering latent community structure in complex networks is a field that has received an enormous amount of attention. Unfortunately, whilst potentially very powerful, unsupervised methods for uncovering labels based on topology alone has…
Healthcare institutes enrich the repository of patients' disease related information in an increasing manner which could have been more useful by carrying out relational analysis. Data mining algorithms are proven to be quite useful in…
Hypergraphs, describing networks where interactions take place among any number of units, are a natural tool to model many real-world social and biological systems. In this work we propose a principled framework to model the organization of…
Emerging research suggests that the extent to which activity spaces -- the collection of an individual's routine activity locations -- overlap provides important information about the functioning of a city and its neighborhoods. To study…
Time series exploration and mining has many applications across several industrial and scientific domains. In this paper, we consider the problem of detecting locally similar pairs and groups, called bundles, over co-evolving time series.…
In theory, a major advantage to the big data approach in studying online communities is that it should be possible to collect a representative random sample from a broadly defined population. However, in practice, data collection processes…
Most existing approaches for community detection require complete information of the graph in a specific scale, which is impractical for many social networks. We propose a novel algorithm that does not embrace the universal approach but…
Predictions of missing links of incomplete networks like protein-protein interaction networks or very likely but not yet existent links in evolutionary networks like friendship networks in web society can be considered as a guideline for…
In many applications, it is common practice to obtain a network from interaction counts by thresholding each pairwise count at a prescribed value. Our analysis calls attention to the dependence of certain methods, notably Newman--Girvan…