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Early prediction of pathological complete response (pCR) following neoadjuvant chemotherapy (NAC) for breast cancer plays a critical role in surgical planning and optimizing treatment strategies. Recently, machine and deep-learning based…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Maya Gilad , Moti Freiman

As early detection of breast cancer strongly favors successful therapeutic outcomes, there is major commercial interest in optimizing breast cancer screening. However, current risk prediction models achieve modest performance and do not…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Manon A. Dorster , Felix J. Dorfner , Mason C. Cleveland , Melisa S. Guelen , Jay Patel , Dania Daye , Jean-Philippe Thiran , Albert E. Kim , Christopher P. Bridge

Automated breast tumor segmentation on the basis of dynamic contrast-enhancement magnetic resonance imaging (DCE-MRI) has shown great promise in clinical practice, particularly for identifying the presence of breast disease. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Lei Zhou , Yuzhong Zhang , Jiadong Zhang , Xuejun Qian , Chen Gong , Kun Sun , Zhongxiang Ding , Xing Wang , Zhenhui Li , Zaiyi Liu , Dinggang Shen

Digital Breast Tomosynthesis (DBT) provides an insight into the fine details of normal fibroglandular tissues and abnormal lesions by reconstructing a pseudo-3D image of the breast. In this respect, DBT overcomes a major limitation of…

Computer Vision and Pattern Recognition · Computer Science 2013-07-24 Guang Yang , John H. Hipwell , David J. Hawkes , Simon R. Arridge

Large-scale, big-variant, high-quality data are crucial for developing robust and successful deep-learning models for medical applications since they potentially enable better generalization performance and avoid overfitting. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zheyuan Zhang , Lanhong Yao , Bin Wang , Debesh Jha , Gorkem Durak , Elif Keles , Alpay Medetalibeyoglu , Ulas Bagci

Breast cancer is the most common malignancy affecting women worldwide and is notable for its morphologic and biologic diversity, with varying risks of recurrence following treatment. The Oncotype DX Breast Recurrence Score test is an…

Magnetic resonance imaging (MRI) plays a vital role in clinical diagnostics, yet it remains hindered by long acquisition times and motion artifacts. Multi-contrast MRI reconstruction has emerged as a promising direction by leveraging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Xinming Fang , Chaoyan Huang , Juncheng Li , Jun Wang , Jun Shi , Guixu Zhang

Diffusion models have shown remarkable success in visual synthesis, but have also raised concerns about potential abuse for malicious purposes. In this paper, we seek to build a detector for telling apart real images from…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Zhendong Wang , Jianmin Bao , Wengang Zhou , Weilun Wang , Hezhen Hu , Hong Chen , Houqiang Li

Detecting misleading patterns in automated diagnostic assistance systems, such as those powered by Artificial Intelligence, is critical to ensuring their reliability, particularly in healthcare. Current techniques for evaluating deep…

Diffusion magnetic resonance imaging is a noninvasive imaging technique that can indirectly infer the microstructure of tissues and provide metrics which are subject to normal variability across subjects. Potentially abnormal values or…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Samuel St-Jean , Max A. Viergever , Alexander Leemans

Compressed sensing Synthetic Aperture Radar (SAR) image formation, formulated as an inverse problem and solved with traditional iterative optimization methods can be very computationally expensive. We investigate the use of denoising…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Odysseas Pappas , Perla Mayo , Andrew Austin , Alin Achim

The differentiation between tumor recurrence and radiation-induced contrast enhancements in post-treatment glioblastoma patients remains a major clinical challenge. Existing approaches rely on clinically sparsely available diffusion MRI or…

Dynamic contrast enhanced computed tomography (CT) is an imaging technique that provides critical information on the relationship of vascular structure and dynamics in the context of underlying anatomy. A key challenge for image processing…

Early detection through imaging and accurate diagnosis is crucial in mitigating the high mortality rate associated with breast cancer. However, locating tumors from low-resolution and high-noise medical images is extremely challenging.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Feiyan Feng , Tianyu Liu , Hong Wang , Jun Zhao , Wei Li , Yanshen Sun

Predicting counterfactual outcomes in longitudinal data, where sequential treatment decisions heavily depend on evolving patient states, is critical yet notoriously challenging due to complex time-dependent confounding and inadequate…

Machine Learning · Statistics 2026-04-15 Farbod Alinezhad , Jianfei Cao , Gary J. Young , Brady Post

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a minimally invasive imaging technique which can be used for characterizing tumor biology and tumor response to radiotherapy. Pharmacokinetic (PK) estimation is widely used…

Image and Video Processing · Electrical Eng. & Systems 2018-03-06 Xia Zhu , Dipanjan Sengupta , Andrew Beers , Kalpathy-Cramer Jayashree , Theodore L. Willke

Tumor segmentation in histopathology images is often complicated by its composition of different histological subtypes and class imbalance. Oversampling subtypes with low prevalence features is not a satisfactory solution since it…

Tracer-kinetic analysis of dynamic contrast-enhanced magnetic resonance imaging data is commonly performed with the well-known Tofts model and nonlinear least squares (NLLS) regression. This approach yields point estimates of model…

Medical Physics · Physics 2020-01-08 Andreas Mittermeier , Birgit Ertl-Wagner , Jens Ricke , Olaf Dietrich , Michael Ingrisch

A method for perfusion imaging with DCE-MRI is developed based on two popular paradigms: the low-rank + sparse model for optimisation-based reconstruction, and the deep unfolding. A learnable algorithm derived from a proximal algorithm is…

Signal Processing · Electrical Eng. & Systems 2024-10-28 Ondřej Mokrý , Jiří Vitouš , Pavel Rajmic , Radovan Jiřík