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Evaluating quantum algorithms at utility-scale - involving more than 100 qubits - is a key step toward advancing real-world applications of quantum computing. In this study, we benchmark seven state-of-the-art quantum emulators employing…

The tremendous advance in computer technology in the past decade has made it possible to achieve the performance of a supercomputer on a very small budget. We have built a multi-CPU cluster of Pentium PC capable of parallel computations…

Distributed, Parallel, and Cluster Computing · Computer Science 2009-11-07 X. Q. Luo , E. B. Gregory , J. C. Yang , Y. L. Wang , D. Chang , Y. Lin

Scaling up quantum devices is a central challenge for realizing practical quantum computation. Modular quantum architectures promise scalability, yet experiments to date have relied on either $\sim\!10^{3}$-qubit monolithic chips or fragile…

Quantum Physics · Physics 2025-11-10 Keren Li , Zidong Lin , Zheng An , Guanru Feng , Zipeng Wu , Shiyao Hou , Jingen Xiang

Hybrid quantum computing systems that combine discrete-variable qubits with continuous-variable qumodes offer promising advantages for quantum simulation, error correction, and sensing applications. However, existing quantum software…

Quantum Physics · Physics 2026-03-12 Jim Furches , Timothy J. Stavenger , Carlos Ortiz Marrero

Classical simulation of quantum computers is an irreplaceable step in the design of quantum algorithms. Exponential simulation costs demand the use of high-performance computing techniques, and in particular distribution, whereby the…

Quantum Physics · Physics 2023-11-06 Tyson Jones , Bálint Koczor , Simon C. Benjamin

Distributed quantum computing is motivated by the difficulty in building large-scale, individual quantum computers. To solve that problem, a large quantum circuit is partitioned and distributed to small quantum computers for execution.…

Quantum Physics · Physics 2023-10-09 Marc Grau Davis , Joaquin Chung , Dirk Englund , Rajkumar Kettimuthu

Quantum computers provide a fundamentally new computing paradigm that promises to revolutionize our ability to solve broad classes of problems. Surprisingly, the basic mathematical structures of gate-based quantum computing, such as unitary…

Quantum Physics · Physics 2019-08-20 Brian R. La Cour , S. Andrew Lanham , Corey I. Ostrove

Advances in quantum simulator technology is increasingly required because research on quantum algorithms is becoming more sophisticated and complex. State vector simulation utilizes CPU and memory resources in computing nodes exponentially…

Quantum Physics · Physics 2024-09-04 Mikio Morita , Yoshinori Tomita , Junpei Koyama , Koichi Kimura

A hybrid scheme that utilizes MPI for distributed memory parallelism and OpenMP for shared memory parallelism is presented. The work is motivated by the desire to achieve exceptionally high Reynolds numbers in pseudospectral computations of…

Computational Physics · Physics 2010-03-24 Pablo D. Mininni , Duane L. Rosenberg , Raghu Reddy , Annick Pouquet

Achieving high-performance computation on quantum systems presents a formidable challenge that necessitates bridging the capabilities between quantum hardware and classical computing resources. This study introduces an innovative…

Quantum Physics · Physics 2024-03-19 Kuan-Cheng Chen , Xiaoren Li , Xiaotian Xu , Yun-Yuan Wang , Chen-Yu Liu

In this work, we propose a framework in the form of a Python package, specifically designed for the analysis of Quantum Machine Learning models. This framework is based on the PennyLane simulator and facilitates the evaluation and training…

Quantum Physics · Physics 2025-09-17 Melvin Strobl , Maja Franz , Eileen Kuehn , Wolfgang Mauerer , Achim Streit

Population pharmacokinetic/pharmacodynamic (PK/PD) modeling traditionally relies on classical ordinary differential equations to simulate drug dynamics. In this work, we reformulate a compartmental PK/PD model as an open quantum system and…

Machine Learning · Computer Science 2026-05-12 Isshaan Singh , Nandan Patel

Quantum circuit simulators have a long tradition of exploiting massive hardware parallelism. Most of the times, parallelism has been supported by special purpose libraries tailored specifically for the quantum circuits. Quantum circuit…

Quantum Physics · Physics 2021-06-29 Oumarou Oumarou , Alexandru Paler , Robert Basmadjian

Quantum circuit simulation is crucial for the development of quantum algorithms, particularly given the high cost and noise limitations of physical quantum hardware. While full-state quantum circuit simulation is commonly employed for…

Quantum Physics · Physics 2026-04-15 Chuan-Chi Wang , Yan-Jie Wang , Chia-Heng Tu , Shih-Hao Hung

Circuit design for quantum machine learning remains a formidable challenge. Inspired by the applications of tensor networks across different fields and their novel presence in the classical machine learning context, one proposed method to…

The big challenge in quantum computing is to realize scalable multi-qubit systems with cross-talk free addressability and efficient coupling of arbitrarily selected qubits. Quantum networks promise a solution by integrating smaller qubit…

The growing demand for robust quantum programming frameworks has unveiled a critical limitation: current large language model (LLM) based quantum code assistants heavily rely on remote APIs, introducing challenges related to privacy,…

Quantum circuit execution is the central task in quantum computation. Due to inherent quantum-mechanical constraints, quantum computing workflows often involve a considerable number of independent measurements over a large set of slightly…

Quantum Physics · Physics 2024-06-06 Daniel Claudino , Dmitry I. Lyakh , Alexander J. McCaskey

We present a framework for differentiable quantum transforms. Such transforms are metaprograms capable of manipulating quantum programs in a way that preserves their differentiability. We highlight their potential with a set of relevant…

Present quantum computers are constrained by limited qubit capacity and restricted physical connectivity, leading to challenges in large-scale quantum computations. Distributing quantum computations across a network of quantum computers is…

Quantum Physics · Physics 2024-05-14 Ranjani G Sundaram , Himanshu Gupta , C. R. Ramakrishnan