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As exascale systems reach unprecedented concurrency, traditional performance analysis tools struggle with the overhead of massive-scale telemetry. We present an accelerated infrastructure for the hpcanalysis framework that leverages a…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-12 Dragana Grbic

Graphics processing units have been extensively used to accelerate classical molecular dynamics simulations. However, there is much less progress on the acceleration of force evaluations for many-body potentials compared to pairwise ones.…

Computational Physics · Physics 2017-06-27 Zheyong Fan , Wei Chen , Ville Vierimaa , Ari Harju

Multi-scale computer simulations combine the computationally efficient classical algorithms with more expensive but also more accurate ab-initio quantum mechanical algorithms. This work describes one implementation of multi-scale…

Computational Physics · Physics 2014-08-20 L. Leukkunen , T. Verho , O. Lopez-Acevedo

Large scale simulations are a key pillar of modern research and require ever-increasing computational resources. Different novel manycore architectures have emerged in recent years on the way towards the exascale era. Performance…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-07-17 Philipp Grete , Forrest W. Glines , Brian W. O'Shea

Molecular Dynamics (MD) codes predict the fundamental properties of matter by following the trajectories of a collection of interacting model particles. To exploit diverse modern manycore hardware, efficient codes must use all available…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-08-04 William R. Saunders , James Grant , Eike H. Müller

The explosive growth of Large Language Models (LLMs), such as GPT-4 with 1.8 trillion parameters, demands a fundamental rethinking of data center architecture to ensure scalability, efficiency, and cost-effectiveness. Our work provides a…

Hardware Architecture · Computer Science 2025-09-09 Jesmin Jahan Tithi , Hanjiang Wu , Avishaii Abuhatzera , Fabrizio Petrini

We have developed molecular dynamics codes for a short-range interaction potential that adopt both the flat-MPI and MPI/OpenMP hybrid parallelizations on the basis of a full domain decomposition strategy. Benchmark simulations involving up…

Computational Physics · Physics 2013-11-28 Hiroshi Watanabe , Masaru Suzuki , Nobuyasu Ito

The molecular dynamics simulation code ls1 mardyn is presented. It is a highly scalable code, optimized for massively parallel execution on supercomputing architectures, and currently holds the world record for the largest molecular…

We employ pressure point analysis and roofline modeling to identify performance bottlenecks and determine an upper bound on the performance of the Canonical Polyadic Alternating Poisson Regression Multiplicative Update (CP-APR MU) algorithm…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-10 S. Isaac Geronimo Anderson , Keita Teranishi , Daniel M. Dunlavy , Jee Choi

We present a novel, hardware-agnostic implementation strategy for lattice Boltzmann (LB) simulations, which yields massive performance on homogeneous and heterogeneous many-core platforms. Based solely on C++17 Parallel Algorithms, our…

Computational Physics · Physics 2021-05-11 Jonas Latt , Christophe Coreixas , Joël Beny

Large Language Models (LLMs) typically generate outputs token by token using a fixed compute budget, leading to inefficient resource utilization. To address this shortcoming, recent advancements in mixture of expert (MoE) models,…

Molecular dynamics simulations are one of the methods in scientific computing that benefit from GPU acceleration. For those devices, SYCL is a promising API for writing portable codes. In this paper, we present the case study of "HAL's MD…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-07 Viktor Skoblin , Felix Höfling , Steffen Christgau

The Liquid Argon Time Projection Chamber (LArTPC) technology is widely used in high energy physics experiments, including the upcoming Deep Underground Neutrino Experiment (DUNE). Accurately simulating LArTPC detector responses is essential…

Instrumentation and Detectors · Physics 2023-03-01 Zhihua Dong , Kyle Knoepfel , Meifeng Lin , Brett Viren , Haiwang Yu

OpenCL is a standard for parallel programming of heterogeneous systems. The benefits of a common programming standard are clear; multiple vendors can provide support for application descriptions written according to the standard, thus…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-23 Pekka Jääskeläinen , Carlos Sánchez de La Lama , Erik Schnetter , Kalle Raiskila , Jarmo Takala , Heikki Berg

This article presents the principles, software architecture, and performance analysis of the GPU port of the lattice Boltzmann software library Palabos (J. Latt et al., "Palabos: Parallel lattice Boltzmann solver", Comput. Math. Appl. 81,…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-12 Jonas Latt , Christophe Coreixas

Modern HPC systems are increasingly relying on greater core counts and wider vector registers. Thus, applications need to be adapted to fully utilize these hardware capabilities. One class of applications that can benefit from this increase…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-06-16 James Vance , Zhen-Hao Xu , Nikita Tretyakov , Torsten Stuehn , Markus Rampp , Sebastian Eibl , Christoph Junghans , André Brinkmann

Scalable and efficient numerical simulations continue to gain importance, as computation is firmly established as the third pillar of discovery, alongside theory and experiment. Meanwhile, the performance of computing hardware grows through…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-26 Pietro Incardona , Antonio Leo , Yaroslav Zaluzhnyi , Rajesh Ramaswamy , Ivo F. Sbalzarini

The applications being developed within the U.S. Exascale Computing Project (ECP) to run on imminent Exascale computers will generate scientific results with unprecedented fidelity and record turn-around time. Many of these codes are based…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-08-04 Lipeng Wan , Axel Huebl , Junmin Gu , Franz Poeschel , Ana Gainaru , Ruonan Wang , Jieyang Chen , Xin Liang , Dmitry Ganyushin , Todd Munson , Ian Foster , Jean-Luc Vay , Norbert Podhorszki , Kesheng Wu , Scott Klasky

High-throughput structure-based screening of drug-like molecules has become a common tool in biomedical research. Recently, acceleration with graphics processing units (GPUs) has provided a large performance boost for molecular docking…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-03-07 Mathialakan Thavappiragasam , Wael Elwasif , Ada Sedova

The unabated growth in AI workload demands is driving the need for concerted advances in compute, memory, and interconnect performance. As traditional semiconductor scaling slows, high-speed interconnects have emerged as the new scaling…

Hardware Architecture · Computer Science 2025-10-21 Mikhail Bernadskiy , Peter Carson , Thomas Graham , Taylor Groves , Ho John Lee , Eric Yeh