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Reliable spike detection and sorting, the process of assigning each detected spike to its originating neuron, is an essential step in the analysis of extracellular electrical recordings from neurons. The volume and complexity of the data…

Neurons and Cognition · Quantitative Biology 2018-09-05 Matthias H. Hennig , Cole Hurwitz , Martino Sorbaro

Spike sorting is an essential process in neural recording, which identifies and separates electrical signals from individual neurons recorded by electrodes in the brain, enabling researchers to study how specific neurons communicate and…

Neurons and Cognition · Quantitative Biology 2025-12-23 Yimu Zhang , Dongqi Han , Yansen Wang , Zhenning Lv , Yu Gu , Dongsheng Li

Spikes in the membrane electrical potentials of neurons play a major role in the functioning of nervous systems of animals. Obtaining the spikes from different neurons has been a challenging problem for decades. Several schemes have been…

Quantitative Methods · Quantitative Biology 2016-02-11 Anupam Mitra , Anagh Pathak , Kaushik Majumdar

Spike sorting is a critical process for decoding large-scale neural activity from extracellular recordings. The advancement of neural probes facilitates the recording of a high number of neurons with an increase in channel counts, arising a…

Signal Processing · Electrical Eng. & Systems 2025-01-31 Yuntao Han , Yihan Pan , Xiongfei Jiang , Cristian Sestito , Shady Agwa , Themis Prodromakis , Shiwei Wang

Spiking neural networks have shown much promise as an energy-efficient alternative to artificial neural networks. However, understanding the impacts of sensor noises and input encodings on the network activity and performance remains…

Computer Vision and Pattern Recognition · Computer Science 2022-06-15 Sami Barchid , José Mennesson , Jason Eshraghian , Chaabane Djéraba , Mohammed Bennamoun

Determining the positions of neurons in an extracellular recording is useful for investigating functional properties of the underlying neural circuitry. In this work, we present a Bayesian modelling approach for localizing the source of…

Neurons and Cognition · Quantitative Biology 2022-01-28 Cole L. Hurwitz , Kai Xu , Akash Srivastava , Alessio P. Buccino , Matthias H. Hennig

Objective: Spike sorting is a fundamental step in analysing extracellular recordings, enabling the isolation of single-neuron activity. However, it remains a challenging problem because extracellular traces mix overlapping spikes from…

Signal Processing · Electrical Eng. & Systems 2025-06-12 Vasileios Georgiadis , Panagiotis C. Petrantonakis

We propose to use neural networks for simultaneous detection and localization of multiple sound sources in human-robot interaction. In contrast to conventional signal processing techniques, neural network-based sound source localization…

Sound · Computer Science 2018-09-18 Weipeng He , Petr Motlicek , Jean-Marc Odobez

Decoding extracellular recordings is a crucial task in electrophysiology and brain-computer interfaces. Spike sorting, which distinguishes spikes and their putative neurons from extracellular recordings, becomes computationally demanding…

Signal Processing · Electrical Eng. & Systems 2024-12-31 Yuntao Han , Shiwei Wang

Spiking neural networks (SNNs) offer both compelling potential advantages, including energy efficiency and low latencies and challenges including the non-differentiable nature of event spikes. Much of the initial research in this area has…

Computer Vision and Pattern Recognition · Computer Science 2022-02-11 Somayeh Hussaini , Michael Milford , Tobias Fischer

An important prerequisite for the analysis of spike synchrony in extracellular recordings is the extraction of single unit activity from the recorded multi unit signal. To identify single units (SUs), potential spikes are detected and…

Neurons and Cognition · Quantitative Biology 2018-11-01 Jeyathevy Sukiban , Nicole Voges , Till A. Dembek , Robin Pauli , Michael Denker , Immo Weber , Lars Timmermann , Sonja Grün

Spike-based neuromorphic hardware promises to reduce the energy consumption of image classification and other deep learning applications, particularly on mobile phones or other edge devices. However, direct training of deep spiking neural…

Neural and Evolutionary Computing · Computer Science 2021-01-27 Christoph Stöckl , Wolfgang Maass

Spike sorting is essential for extracting neuronal information from neural signals and understanding brain function. With the advent of high-density microelectrode arrays (HDMEAs), the challenges and opportunities in multi-channel spike…

Signal Processing · Electrical Eng. & Systems 2024-12-30 Yuntao Han , Shiwei Wang , Alister Hamilton

Neuromorphic computing is henceforth a major research field for both academic and industrial actors. As opposed to Von Neumann machines, brain-inspired processors aim at bringing closer the memory and the computational elements to…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Maxence Bouvier , Alexandre Valentian , Thomas Mesquida , François Rummens , Marina Reyboz , Elisa Vianello , Edith Beigné

With the increasing application scope of spiking neural networks (SNN), the complexity of SNN models has surged, leading to an exponential growth in demand for AI computility. As the new generation computing architecture of the neural…

Hardware Architecture · Computer Science 2025-05-21 Xueke Zhu , Wenjie Lin , Yanyu Lin , Yunhao Ma , Wenxiang Cheng , Zhengyu Ma , Yonghong Tian , Huihui Zhou

Developing electrophysiological recordings of brain neuronal activity and their analysis provide a basis for exploring the structure of brain function and nervous system investigation. The recorded signals are typically a combination of…

Neurons and Cognition · Quantitative Biology 2019-11-01 Sahar Hojjatinia , Constantino M. Lagoa

Spike sorting is a crucial step in decoding multichannel extracellular neural signals, enabling the identification of individual neuronal activity. A key challenge in brain-machine interfaces (BMIs) is achieving real-time, low-power spike…

Neural and Evolutionary Computing · Computer Science 2025-07-01 Alexis Melot , Sean U. N. Wood , Yannick Coffinier , Pierre Yger , Fabien Alibart

Spike sorting algorithms are used to separate extracellular recordings of neuronal populations into single-unit spike activities. The development of customized hardware implementing spike sorting algorithms is burgeoning. However, there is…

Machine Learning · Computer Science 2025-01-30 Tim Zhang , Corey Lammie , Mostafa Rahimi Azghadi , Amirali Amirsoleimani , Majid Ahmadi , Roman Genov

Spikes are the currency in central nervous systems for information transmission and processing. They are also believed to play an essential role in low-power consumption of the biological systems, whose efficiency attracts increasing…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Qiang Yu , Shenglan Li , Huajin Tang , Longbiao Wang , Jianwu Dang , Kay Chen Tan

Artificial neural networks are being proposed as models of parts of the brain. The networks are compared to recordings of biological neurons, and good performance in reproducing neural responses is considered to support the model's…

Neurons and Cognition · Quantitative Biology 2023-09-01 Yena Han , Tomaso Poggio , Brian Cheung
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