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The detailed reconstruction of neural anatomy for connectomics studies requires a combination of resolution and large three-dimensional data capture provided by serial section electron microscopy (ssEM). The convergence of high throughput…

Computer Vision and Pattern Recognition · Computer Science 2017-11-21 Arthur W. Wetzel , Jennifer Bakal , Markus Dittrich , David G. C. Hildebrand , Josh L. Morgan , Jeff W. Lichtman

A finite element method (FEM) for solving the complex valued k({\omega}) vs. {\omega} dispersion curve of a 3D metamaterial/photonic crystal system is presented. This 3D method is a generalization of a previously reported 2D eigenvalue…

Materials Science · Physics 2015-05-28 Chris Fietz , Yaroslav Urzhumov , Gennady Shvets

Medical image colorization can greatly enhance the interpretability of the underlying imaging modality and provide insights into human anatomy. The objective of medical image colorization is to transfer a diverse spectrum of colors…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Mayuri Mathur , Anav Chaudhary , Saurabh Kumar Gupta , Ojaswa Sharma

Federated learning (FL) achieves collaborative learning without the need for data sharing, thus preventing privacy leakage. To extend FL into a fully decentralized algorithm, researchers have applied distributed optimization algorithms to…

Networking and Internet Architecture · Computer Science 2023-12-20 Akihito Taya , Yuuki Nishiyama , Kaoru Sezaki

Cancer, with its inherent heterogeneity, is commonly categorized into distinct subtypes based on unique traits, cellular origins, and molecular markers specific to each type. However, current studies primarily rely on complete multi-omics…

Machine Learning · Computer Science 2024-11-26 Yingxuan Ren , Fengtao Ren , Bo Yang

We discuss a polymer model for the 3D organization of human chromosomes. A chromosome is represented by a string of beads, with each bead being "colored" according to 1D bioinformatic data (e.g., chromatin state, histone modification, GC…

Biological Physics · Physics 2020-10-15 C. A. Brackley , D. Michieletto , F. Mouvet , J. Johnson , S. Kelly , P. R. Cook , D. Marenduzzo

Registration is widely used in image-guided therapy and image-guided surgery to estimate spatial correspondences between organs of interest between planning and treatment images. However, while high-quality computed tomography (CT) images…

Image and Video Processing · Electrical Eng. & Systems 2022-03-11 Lin Tian , Connor Puett , Peirong Liu , Zhengyang Shen , Stephen R. Aylward , Yueh Z. Lee , Marc Niethammer

3D single object tracking plays a crucial role in computer vision. Mainstream methods mainly rely on point clouds to achieve geometry matching between target template and search area. However, textureless and incomplete point clouds make it…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Zhiheng Li , Yubo Cui , Yu Lin , Zheng Fang

Hematoxylin and eosin (H&E) staining is the clinical standard for assessing tissue morphology, but it lacks molecular-level diagnostic information. In contrast, immunohistochemistry (IHC) provides crucial insights into biomarker expression,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Jingsong Liu , Xiaofeng Deng , Han Li , Azar Kazemi , Christian Grashei , Gesa Wilkens , Xin You , Tanja Groll , Nassir Navab , Carolin Mogler , Peter J. Schüffler

FAIR Digital Object (FDO) is an emerging concept that is highlighted by European Open Science Cloud (EOSC) as a potential candidate for building a ecosystem of machine-actionable research outputs. In this work we systematically evaluate FDO…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-07 Stian Soiland-Reyes , Carole Goble , Paul Groth

The count of mitotic figures (MFs) observed in hematoxylin and eosin (H&E)-stained slides is an important prognostic marker as it is a measure for tumor cell proliferation. However, the identification of MFs has a known low inter-rater…

Volumetric biological imaging often involves compromising high temporal resolution at the expense of high spatial resolution when popular scanning methods are used to capture 3D information. We introduce an integrated experimental and image…

While model architectures and training strategies have become more generic and flexible with respect to different data modalities over the past years, a persistent limitation lies in the assumption of fixed quantities and arrangements of…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Lisa Weijler , Florian Kowarsch , Michael Reiter , Pedro Hermosilla , Margarita Maurer-Granofszky , Michael Dworzak

Multi-institutional collaborations are key for learning generalizable MRI synthesis models that translate source- onto target-contrast images. To facilitate collaboration, federated learning (FL) adopts decentralized training and mitigates…

Image and Video Processing · Electrical Eng. & Systems 2022-08-24 Onat Dalmaz , Usama Mirza , Gökberk Elmas , Muzaffer Özbey , Salman UH Dar , Emir Ceyani , Salman Avestimehr , Tolga Çukur

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a critical imaging method for capturing and modeling tissue microarchitecture at a millimeter scale. A common practice to model the measured DW-MRI signal is via fiber orientation…

We present an extension of TRAPHIC, the method for radiative transfer of ionising radiation in smoothed particle hydrodynamics simulations that we introduced in Pawlik & Schaye (2008). The new version keeps all advantages of the original…

Instrumentation and Methods for Astrophysics · Physics 2011-05-10 Andreas H. Pawlik , Joop Schaye

In order to efficiently image a non-absorbing sample (a phase object), dedicated phase contrast optics are required. Typically, these optics are designed with the assumption that the sample is weakly scattering, implying a linear relation…

Optics · Physics 2020-10-22 Stewart Koppell , Mark Kasevich

Digitization, i.e., the process of converting information into a digital format, may provide various opportunities (e.g., increase in productivity, disaster recovery, and environmentally friendly solutions) and challenges for businesses. In…

Computer Vision and Pattern Recognition · Computer Science 2021-06-09 Nouna Khandan

Circular dichroism (CD) sensing plays a pivotal role in probing molecular chirality in biomedical sciences. However, engineering superchiral electromagnetic fields that can reliably amplify the faint signatures of chiral analytes remains…

Photon-counting computed tomography (PCCT) has emerged as a promising imaging technique, enabling spectral imaging and material decomposition (MD). However, images typically suffer from a low signal-to-noise ratio (SNR) due to constraints…

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