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This paper explores the use of a soft ground-truth mask ("soft mask'') to train a Fully Convolutional Neural Network (FCNN) for segmentation of Multiple Sclerosis (MS) lesions. Detection and segmentation of MS lesions is a complex task…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Eytan Kats , Jacob Goldberger , Hayit Greenspan

Major depressive disorder (MDD) is one of the most common mental disorders, with significant impacts on many daily activities and quality of life. It stands as one of the most common mental disorders globally and ranks as the second leading…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Nojod M. Alotaibi , Areej M. Alhothali , Manar S. Ali

Alzheimer's disease (AD) is one of the most common public health issues the world is facing today. This disease has a high prevalence primarily in the elderly accompanying memory loss and cognitive decline. AD detection is a challenging…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Zahraa Sh. Aaraji , Hawraa H. Abbas

To date, several automated strategies for identification/segmentation of Multiple Sclerosis (MS) lesions with the use of Magnetic Resonance Imaging (MRI) have been presented, but they are outperformed by human experts, from whom they act…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Giuseppe Placidi , Luigi Cinque , Daniela Iacoviello , Filippo Mignosi , Matteo Polsinelli

Ischaemic stroke is a medical condition caused by occlusion of blood supply to the brain tissue thus forming a lesion. A lesion is zoned into a core associated with irreversible necrosis typically located at the center of the lesion, while…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Rachana Sathish , Ronnie Rajan , Anusha Vupputuri , Nirmalya Ghosh , Debdoot Sheet

Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

Machine Learning · Computer Science 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh

Multiple sclerosis is an inflammatory disorder of the central nervous system. Quantitative MRI has huge potential to provide intrinsic and normative values of tissue properties useful for diagnosis, prognosis and ultimately clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-03 Haykel Snoussi , Julien Cohen-Adad , Benoit Combes , Elise Bannier , Slimane Tounekti , Anne Kerbrat , Christian Barillot , Emmanuel Caruyer

Alzheimer's disease (AD) is the most common type of dementia accompanied with brain atrophy. Structural measurements of brain atrophy in specific brain structures such as hippocampus using magnetic resonance imaging (MRI) have been reported…

Medical Physics · Physics 2016-05-10 Kenya Murase , Naohiko Gondo , Tsutomu Soma

Brain lesion volume measured on T2 weighted MRI images is a clinically important disease marker in multiple sclerosis (MS). Manual delineation of MS lesions is a time-consuming and highly operator-dependent task, which is influenced by…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Hang Zhang , Jinwei Zhang , Qihao Zhang , Jeremy Kim , Shun Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Mert R. Sabuncu , Yi Wang

The most frequent kind of dementia of the nervous system, Alzheimer's disease, weakens several brain processes (such as memory) and eventually results in death. The clinical study uses magnetic resonance imaging to diagnose AD. Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Sarasadat Foroughipoor , Kimia Moradi , Hamidreza Bolhasani

Accurately measuring the evolution of Multiple Sclerosis (MS) with magnetic resonance imaging (MRI) critically informs understanding of disease progression and helps to direct therapeutic strategy. Deep learning models have shown promise…

Machine Learning (ML) and Deep Learning (DL) have shown significant promise in healthcare, particularly in medical image segmentation, which is crucial for accurate disease diagnosis and treatment planning. Despite their potential,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Chamani Shiranthika , Zahra Hafezi Kafshgari , Hadi Hadizadeh , Parvaneh Saeedi

The accurate understanding of ischemic stroke lesions is critical for efficient therapy and prognosis of stroke patients. Magnetic resonance imaging (MRI) is sensitive to acute ischemic stroke and is a common diagnostic method for stroke.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 R. P. Chowdhury , T. Rahman

Lesions that appear hyperintense in both Fluid Attenuated Inversion Recovery (FLAIR) and T2-weighted magnetic resonance images (MRIs) of the human brain are common in the brains of the elderly population and may be caused by ischemia or…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Hans E. Atlason , Askell Love , Sigurdur Sigurdsson , Vilmundur Gudnason , Lotta M. Ellingsen

Multiple sclerosis (MS) lesions occupy a small fraction of the brain volume, and are heterogeneous with regards to shape, size and locations, which poses a great challenge for training deep learning based segmentation models. We proposed a…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Hang Zhang , Jinwei Zhang , Rongguang Wang , Qihao Zhang , Susan A. Gauthier , Pascal Spincemaille , Thanh D. Nguyen , Yi Wang

In recent years, data-driven machine learning (ML) methods have revolutionized the computer vision community by providing novel efficient solutions to many unsolved (medical) image analysis problems. However, due to the increasing privacy…

Image and Video Processing · Electrical Eng. & Systems 2021-03-08 Cosmin I. Bercea , Benedikt Wiestler , Daniel Rueckert , Shadi Albarqouni

The Lewy body dementia (LBD) is the second most common neurodegenerative dementia after Alzheimer's disease (AD). Early differentiation between AD and LBD is crucial because they require different treatment approaches, but this is…

Machine Learning · Computer Science 2025-03-12 Jing Zhang , Xiaowei Yu , Tong Chen , Chao Cao , Mingheng Chen , Yan Zhuang , Yanjun Lyu , Lu Zhang , Li Su , Tianming Liu , Dajiang Zhu

Segmentation is essential for medical image analysis to identify and localize diseases, monitor morphological changes, and extract discriminative features for further diagnosis. Skin cancer is one of the most common types of cancer…

Image and Video Processing · Electrical Eng. & Systems 2022-09-02 Hritam Basak , Rohit Kundu , Ram Sarkar

Diagnosing erythema migrans (EM) skin lesion, the most common early symptom of Lyme disease using deep learning techniques can be effective to prevent long-term complications. Existing works on deep learning based EM recognition only…

Brain lesions are abnormalities or injuries in brain tissue that are often detectable using magnetic resonance imaging (MRI), which reveals structural changes in the affected areas. This broad definition of brain lesions includes areas of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Omar Zamzam , Haleh Akrami , Anand Joshi , Richard Leahy