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The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…
Pulmonary pathologies are a significant global health concern, often leading to fatal outcomes if not diagnosed and treated promptly. Chest radiography serves as a primary diagnostic tool, but the availability of experienced radiologists…
Lung cancer has the highest mortality rate of deadly cancers in the world. Early detection is essential to treatment of lung cancer. However, detection and accurate diagnosis of pulmonary nodules depend heavily on the experiences of…
Objectives: To compare artificial intelligence (AI) as a second reader in detecting lung nodules on chest X-rays (CXR) versus radiologists of two binational institutions, and to evaluate AI performance when using two different modes:…
Artificial intelligence (AI) systems accelerate medical workflows and improve diagnostic accuracy in healthcare, serving as second-opinion systems. However, the unpredictability of AI errors poses a significant challenge, particularly in…
The ability of deep learning to predict with uncertainty is recognized as key for its adoption in clinical routines. Moreover, performance gain has been enabled by modelling uncertainty according to empirical evidence. While previous work…
Uncertainty is a fundamental challenge in medical practice, but current medical AI systems fail to explicitly quantify or communicate uncertainty in a way that aligns with clinical reasoning. Existing XAI works focus on interpreting model…
Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…
In recent years, AI systems in the medical domain have advanced significantly. However, despite outperforming humans, they are rarely used in practice since it is often not clear how they make their decisions. Optimal explanation and…
Deep learning (DL) models have received particular attention in medical imaging due to their promising pattern recognition capabilities. However, Deep Neural Networks (DNNs) require a huge amount of data, and because of the lack of…
Trustworthy artificial intelligence (AI) is essential in healthcare, particularly for high-stakes tasks like medical image segmentation. Explainable AI and uncertainty quantification significantly enhance AI reliability by addressing key…
The full acceptance of Deep Learning (DL) models in the clinical field is rather low with respect to the quantity of high-performing solutions reported in the literature. Particularly, end users are reluctant to rely on the rough…
While previous studies have demonstrated the potential of AI to diagnose diseases in imaging data, clinical implementation is still lagging behind. This is partly because AI models require training with large numbers of examples only…
Patients undergoing chest X-rays (CXR) often endure multiple lung diseases. When evaluating a patient's condition, due to the complex pathologies, subtle texture changes of different lung lesions in images, and patient condition…
Lung cancer remains one of the leading causes of morbidity and mortality worldwide, making early diagnosis critical for improving therapeutic outcomes and patient prognosis. Computer-aided diagnosis systems, which analyze computed…
Deep neural networks are increasingly being used for computer-aided diagnosis, but erroneous diagnoses can be extremely costly for patients. We propose a learning to defer with uncertainty (LDU) algorithm which identifies patients for whom…
Recent research has supported that system explainability improves user trust and willingness to use medical AI for diagnostic support. In this paper, we use chest disease diagnosis based on X-Ray images as a case study to investigate user…
Deep learning models show significant potential for advancing AI-assisted medical diagnostics, particularly in detecting lung cancer through medical image modalities such as chest X-rays. However, the black-box nature of these models poses…
Deep learning integration into medical imaging systems has transformed disease detection and diagnosis processes with a focus on pneumonia identification. The study introduces an intricate deep learning system using Convolutional Neural…
With the ongoing development of deep learning, an increasing number of AI models have surpassed the performance levels of human clinical practitioners. However, the prevalence of AI diagnostic products in actual clinical practice remains…