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Nucleic acid sensing is crucial for advancing diagnostics, therapeutic monitoring and molecu-lar biology research, by enabling the precise identification of DNA and RNA interactions. Here, we present an innovative sensing platform based on…

Enzymes are cellular protein machines using a variety of conformational changes to power fast biochemical catalysis. Our goal is to exploit the single-spin properties of the luminescent NV (nitrogen-vacancy) center in nanodiamonds to reveal…

Quantitative Methods · Quantitative Biology 2024-01-25 Ivan Perez , Anke Krueger , Joerg Wrachtrup , Fedor Jelezko , Michael Börsch

Nanodiamonds containing nitrogen-vacancy (NV) centers can serve as colloidal quantum sensors of local fields in biological and chemical environments. However, nanodiamond surfaces are challenging to modify without degrading their colloidal…

A fully integrated quantum optical technology requires active quantum systems incorporated into resonant optical microstructures and inter-connected in three dimensions via photonic wires. Nitrogen vacancy-centres (NV-centres) in diamond…

The detection of individual molecules and their dynamics has been a long-standing challenge in the field of nanotechnology. In this work, we present a method that utilizes a nitrogen vacancy (NV) center and a dangling-bond on the diamond…

Quantum Physics · Physics 2023-12-15 A. Biteri-Uribarren , P. Alsina-Bolívar , C. Munuera-Javaloy , R. Puebla , J. Casanova

The negatively-charged nitrogen-vacancy center (NV) in diamond forms a versatile system for quantum sensing applications. Combining the advantageous properties of this atomic-sized defect with scanning probe techniques such as atomic force…

Mesoscale and Nanoscale Physics · Physics 2018-12-26 Philipp Fuchs , Michel Challier , Elke Neu

Magnetometers based on nitrogen-vacancy (NV) centers in diamond have emerged as the most important solid-state quantum sensors. However, ensembles are limited in optical contrast to typically a few percent and high-sensitivity variants…

One of the biggest challenges to implement quantum protocols and quantum information processing (QIP) is achieving long coherence times, usually requiring systems at ultra-low temperatures. The nitrogen-vacancy (NV) center in diamond is a…

Achieving fast, sensitive, and parallel measurement of a large number of quantum particles is an essential task in building large-scale quantum platforms for different quantum information processing applications such as sensing,…

Quantum sensors have attracted broad interest in the quest towards sub-micronscale NMR spectroscopy. Such sensors predominantly operate at low magnetic fields. Instead, however, for high resolution spectroscopy, the high-field regime is…

Nitrogen-vacancy (NV) centers in diamond have emerged as quantum sensors capable of detecting nuclear magnetic resonance (NMR) signals at unprecedented length scales, ranging from picoliter sample volumes down to single spins at the diamond…

Chemical Physics · Physics 2025-01-07 Nick R. von Grafenstein , Karl D. Briegel , Jorge Casanova , Dominik B. Bucher

Diamond colour centres are promising optically-addressable solid state spins that can be matter-qubits, mediate deterministic interaction between photons and act as single photon emitters. Useful quantum computers will comprise millions of…

Many spintronic, magnetic-memory, and neuromorphic devices rely on spatially varying magnetic fields. Quantitatively imaging these fields with full vector information over extended areas remains a major challenge. Existing probes either…

The nitrogen-vacancy (NV) center in diamond allows room-temperature wide-field quantum magnetometry and metrology for a small volume, which is an important technology for applications in biology. Although coherence of the NV center has a…

Nitrogen-vacancy (NV) centers in diamond can be used as quantum sensors to image the magnetic field with nanoscale resolution. However, nanoscale electric-field mapping has not been achieved so far because of the relatively weak coupling…

Mesoscale and Nanoscale Physics · Physics 2021-05-04 Ke Bian , Wentian Zheng , Xianzhe Zeng , Xiakun Chen , Rainer Stohr , Andrej Denisenko , Sen Yang , Joerg Wrachtrup , Ying Jiang

Optical biosensors are indispensable in medical and environmental diagnostics, yet existing approaches are fundamentally limited in their sensitivity due to ensemble-averaged measurements. Digital biosensing has emerged as a promising…

Diamond is a solid-state platform to develop quantum technologies, but it has been a long-standing problem that the current understanding of quantum states in diamond is mostly limited to single-electron pictures. Here, we combine the full…

Chemical Physics · Physics 2023-07-19 Yilin Chen , Tonghuan Jiang , Haoxiang Chen , Erxun Han , Ali Alavi , Kuang Yu , En-Ge Wang , Ji Chen

Negatively charged nitrogen-vacancy (NV) center in diamond is the representative solid state defect qubit for quantum information science, offering long coherence time at room temperature. To achieve high sensitivity and spatial resolution,…

Materials Science · Physics 2025-08-12 Pei Li , Guanjian Hu , Xiao Yu , Bing Huang , Song Li

Nitrogen-vacancy centers in diamond allow measurement of environment properties such as temperature, magnetic and electric fields at nanoscale level, of utmost relevance for several research fields, ranging from nanotechnologies to…

Quantum sensing takes advantage of well controlled quantum systems for performing measurements with high sensitivity and precision. We have implemented a concept for quantum sensing with arbitrary frequency resolution, independent of the…

Quantum Physics · Physics 2017-06-07 J. M. Boss , K. S. Cujia , J. Zopes , C. L. Degen