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Related papers: NucEL: Single-Nucleotide ELECTRA-Style Genomic Pre…

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Recent studies have demonstrated the overwhelming advantage of cross-lingual pre-trained models (PTMs), such as multilingual BERT and XLM, on cross-lingual NLP tasks. However, existing approaches essentially capture the co-occurrence among…

Computation and Language · Computer Science 2021-03-23 Xiangpeng Wei , Rongxiang Weng , Yue Hu , Luxi Xing , Heng Yu , Weihua Luo

Knowing whether a Quantum Machine Learning model would perform well on a given dataset before training it can help to save critical resources. However, gathering a priori information about model performance (e.g., training speed, critical…

Quantum Physics · Physics 2025-03-05 Francesco Scala , Christa Zoufal , Dario Gerace , Francesco Tacchino

Unsupervised cell type identification is crucial for uncovering and characterizing heterogeneous populations in single cell omics studies. Although a range of clustering methods have been developed, most focus exclusively on intrinsic…

Artificial Intelligence · Computer Science 2025-12-12 Liang Peng , Haopeng Liu , Yixuan Ye , Cheng Liu , Wenjun Shen , Si Wu , Hau-San Wong

Nuclei classification is a critical step in computer-aided diagnosis with histopathology images. In the past, various methods have employed graph neural networks (GNN) to analyze cell graphs that model inter-cell relationships by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Wei Lou , Guanbin Li , Xiang Wan , Haofeng Li

Pre-trained Programming Language Models (PPLMs) achieved many recent states of the art results for many code-related software engineering tasks. Though some studies use data flow or propose tree-based models that utilize Abstract Syntax…

Software Engineering · Computer Science 2023-03-14 Iman Saberi , Fatemeh H. Fard

Large pre-trained language models (LMs) are known to encode substantial amounts of linguistic information. However, high-level reasoning skills, such as numerical reasoning, are difficult to learn from a language-modeling objective only.…

Computation and Language · Computer Science 2020-04-10 Mor Geva , Ankit Gupta , Jonathan Berant

Pre-trained masked language models have demonstrated remarkable ability as few-shot learners. In this paper, as an alternative, we propose a novel approach to few-shot learning with pre-trained token-replaced detection models like ELECTRA.…

Computation and Language · Computer Science 2023-03-22 Zicheng Li , Shoushan Li , Guodong Zhou

Accurate comprehension and controllable generation of emotion and rhetoric are pivotal for enhancing the reasoning capabilities of large language models (LLMs). Existing studies mostly rely on external optimizations, lacking in-depth…

Computation and Language · Computer Science 2026-04-21 Li Zheng , Xin Zhang , Shuyi He , Fei Li , Chong Teng , Jiangming Yang , Donghong Ji , Zhuang Li

Effective training of today's large language models (LLMs) depends on large batches and long sequences for throughput and accuracy. To handle variable-length sequences on hardware accelerators, it is common practice to introduce padding…

Computation and Language · Computer Science 2022-10-07 Mario Michael Krell , Matej Kosec , Sergio P. Perez , Andrew Fitzgibbon

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Designing a neural network architecture for molecular representation is crucial for AI-driven drug discovery and molecule design. In this work, we propose a new framework for molecular representation learning. Our contribution is threefold:…

Machine Learning · Computer Science 2022-10-18 Jiye Kim , Seungbeom Lee , Dongwoo Kim , Sungsoo Ahn , Jaesik Park

The extreme learning machine (ELM) method can yield highly accurate solutions to linear/nonlinear partial differential equations (PDEs), but requires the last hidden layer of the neural network to be wide to achieve a high accuracy. If the…

Numerical Analysis · Mathematics 2022-05-17 Naxian Ni , Suchuan Dong

Linguistic sequence labeling is a general modeling approach that encompasses a variety of problems, such as part-of-speech tagging and named entity recognition. Recent advances in neural networks (NNs) make it possible to build reliable…

Computation and Language · Computer Science 2017-11-27 Liyuan Liu , Jingbo Shang , Frank F. Xu , Xiang Ren , Huan Gui , Jian Peng , Jiawei Han

Large language models (LLMs) have shown that generative pretraining can distill vast world knowledge into compact token representations. While LLMs encapsulate extensive world knowledge, they remain limited in modeling the behavioral…

Machine Learning · Computer Science 2026-03-31 Guilin Li , Yun Zhang , Xiuyuan Chen , Chengqi Li , Bo Wang , Linghe Kong , Wenjia Wang , Weiran Huang , Matthias Hwai Yong Tan

Pre-trained models for programming language have achieved dramatic empirical improvements on a variety of code-related tasks such as code search, code completion, code summarization, etc. However, existing pre-trained models regard a code…

Tokenization sits at the boundary between high-throughput genomic input and GPU compute, posing challenges in both algorithm design and system throughput. Overlapping k-mer tokenization can introduce information leakage under masked…

Genomics · Quantitative Biology 2026-01-12 Eliatan Niktab , Hardip Patel

Successful methods for unsupervised neural machine translation (UNMT) employ crosslingual pretraining via self-supervision, often in the form of a masked language modeling or a sequence generation task, which requires the model to align the…

Computation and Language · Computer Science 2021-04-15 Alexandra Chronopoulou , Dario Stojanovski , Alexander Fraser

Electron Cryo-Tomography (ECT) enables 3D visualization of macromolecule structure inside single cells. Macromolecule classification approaches based on convolutional neural networks (CNN) were developed to separate millions of…

Quantitative Methods · Quantitative Biology 2018-03-28 Jialiang Guo , Bo Zhou , Xiangrui Zeng , Zachary Freyberg , Min Xu

Large language models have made remarkable progress in the field of molecular science, particularly in understanding and generating functional small molecules. This success is largely attributed to the effectiveness of molecular…

Biomolecules · Quantitative Biology 2025-03-14 Zicheng Ma , Chuanliu Fan , Zhicong Wang , Zhenyu Chen , Xiaohan Lin , Yanheng Li , Shihao Feng , Jun Zhang , Ziqiang Cao , Yi Qin Gao

Model Agnostic Meta-Learning (MAML) has emerged as a standard framework for meta-learning, where a meta-model is learned with the ability of fast adapting to new tasks. However, as a double-looped optimization problem, MAML needs to…

Machine Learning · Computer Science 2021-02-10 Yufan Zhou , Zhenyi Wang , Jiayi Xian , Changyou Chen , Jinhui Xu
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