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Graphical Gaussian models are popular tools for the estimation of (undirected) gene association networks from microarray data. A key issue when the number of variables greatly exceeds the number of samples is the estimation of the matrix of…

Methodology · Statistics 2010-08-13 Nicole Kraemer , Juliane Schaefer , Anne-Laure Boulesteix

Gaussian Graphical Models (GGMs) are popular tools for studying network structures. However, many modern applications such as gene network discovery and social interactions analysis often involve high-dimensional noisy data with outliers or…

Machine Learning · Statistics 2015-10-30 Eunho Yang , Aurélie C. Lozano

Classically, statistical datasets have a larger number of data points than features ($n > p$). The standard model of classical statistics caters for the case where data points are considered conditionally independent given the parameters.…

Machine Learning · Statistics 2022-03-16 Sijia Li , Martín López-García , Neil D. Lawrence , Luisa Cutillo

The sparse precision matrix plays an essential role in the Gaussian graphical model since a zero off-diagonal element indicates conditional independence of the corresponding two variables given others. In the Gaussian graphical model, many…

Computation · Statistics 2022-03-30 Seunghwan Lee , Sang Cheol Kim , Donghyeon Yu

In recent literature, the Gaussian Graphical model (GGM; Lauritzen, 1996),a network of partial correlation coefficients, has been used to capture potential dynamic relationships between observed variables. The GGM can be estimated using…

Methodology · Statistics 2017-09-25 Sacha Epskamp

Microbiome data require statistical models that can simultaneously decode microbes' reaction to the environment and interactions among microbes. While a multiresponse linear regression model seems like a straight-forward solution, we argue…

Applications · Statistics 2022-07-26 Yunyi Shen , Claudia Solis-Lemus

Gaussian graphical models are used for determining conditional relationships between variables. This is accomplished by identifying off-diagonal elements in the inverse-covariance matrix that are non-zero. When the ratio of variables (p) to…

Applications · Statistics 2018-08-07 Donald R. Williams , Juho Piironen , Aki Vehtari , Philippe Rast

Graphical modeling explores dependences among a collection of variables by inferring a graph that encodes pairwise conditional independences. For jointly Gaussian variables, this translates into detecting the support of the precision…

Methodology · Statistics 2018-02-16 Shota Katayama , Hironori Fujisawa , Mathias Drton

We apply the network Lasso to classify partially labeled data points which are characterized by high-dimensional feature vectors. In order to learn an accurate classifier from limited amounts of labeled data, we borrow statistical strength,…

Machine Learning · Computer Science 2019-03-27 Nguyen Tran , Henrik Ambos , Alexander Jung

The paper demonstrates the use of LASSO-based estimation in network models. Taking the Exponential Random Graph Model (ERGM) as a flexible and widely used model for network data analysis, the paper focuses on the question of how to specify…

Methodology · Statistics 2024-09-13 Sergio Buttazzo , Göran Kauermann

Graphical models are frequently used to explore networks, such as genetic networks, among a set of variables. This is usually carried out via exploring the sparsity of the precision matrix of the variables under consideration. Penalized…

Applications · Statistics 2009-08-17 Jianqing Fan , Yang Feng , Yichao Wu

We propose Partial Correlation Screening (PCS) as a new row-by-row approach to estimating a large precision matrix $\Omega$. To estimate the $i$-th row of $\Omega$, $1 \leq i \leq p$, PCS uses a Screen step and a Clean step. In the Screen…

Methodology · Statistics 2014-09-12 Shiqiong Huang , Jiashun Jin , Zhigang Yao

In Gaussian graphical models, the likelihood equations must typically be solved iteratively. We investigate two algorithms: A version of iterative proportional scaling which avoids inversion of large matrices, and an algorithm based on…

Computation · Statistics 2023-12-12 Søren Højsgaard , Steffen Lauritzen

In Gaussian graphical models, conditional independence and partial correlations are natural inferential targets for understanding direct relationships in multivariate data. No comparable framework exists for spatial processes, where…

Methodology · Statistics 2026-04-14 Michele Peruzzi

Graphical modelling techniques based on sparse selection have been applied to infer complex networks in many fields, including biology and medicine, engineering, finance, and social sciences. One structural feature of some of the networks…

Statistics Theory · Mathematics 2020-03-03 Annaliza McGillivray , Abbas Khalili , David A. Stephens

We propose a new approach for the modeling large datasets of nonstationary spatial processes that combines a latent low rank process and a sparse covariance model. The low rank component coefficients are endowed with a flexible graphical…

Methodology · Statistics 2025-10-08 Matthew LeDuc , William Kleiber , Tomoko Matsuo

Anomalies and outliers are common in real-world data, and they can arise from many sources, such as sensor faults. Accordingly, anomaly detection is important both for analyzing the anomalies themselves and for cleaning the data for further…

Machine Learning · Statistics 2018-11-13 Haitao Liu , Randy C. Paffenroth , Jian Zou , Chong Zhou

Gaussian graphical regression is a powerful means that regresses the precision matrix of a Gaussian graphical model on covariates, permitting the numbers of the response variables and covariates to far exceed the sample size. Model fitting…

Methodology · Statistics 2022-05-24 Jingfei Zhang , Yi Li

The network Lasso (nLasso) has been proposed recently as an efficient learning algorithm for massive networked data sets (big data over networks). It extends the well-known least absolute shrinkage and selection operator (Lasso) from…

Machine Learning · Computer Science 2019-07-24 Alexander Jung , Nguyen Tran

Many Machine Learning algorithms are formulated as regularized optimization problems, but their performance hinges on a regularization parameter that needs to be calibrated to each application at hand. In this paper, we propose a general…

Machine Learning · Statistics 2021-03-31 Mike Laszkiewicz , Asja Fischer , Johannes Lederer