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Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang

Generative modelling and synthetic data can be a surrogate for real medical imaging datasets, whose scarcity and difficulty to share can be a nuisance when delivering accurate deep learning models for healthcare applications. In recent…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Virginia Fernandez , Walter Hugo Lopez Pinaya , Pedro Borges , Mark S. Graham , Tom Vercauteren , M. Jorge Cardoso

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Reconciling symbolic and distributed representations is a crucial challenge that can potentially resolve the limitations of current deep learning. Remarkable advances in this direction have been achieved recently via generative…

Machine Learning · Computer Science 2021-02-09 Jindong Jiang , Sungjin Ahn

Generative modeling of anatomical structures plays a crucial role in virtual imaging trials, which allow researchers to perform studies without the costs and constraints inherent to in vivo and phantom studies. For clinical relevance,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Bram de Wilde , Max T. Rietberg , Guillaume Lajoinie , Jelmer M. Wolterink

Ultrasound and radar signals are highly beneficial for medical imaging as they are non-invasive and non-ionizing. Traditional imaging techniques have limitations in terms of contrast and physical interpretation. Quantitative medical imaging…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Tom Sharon , Yonina C. Eldar

Ultrasound imaging makes use of backscattering of waves during their interaction with scatterers present in biological tissues. Simulation of synthetic ultrasound images is a challenging problem on account of inability to accurately model…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 Francis Tom , Debdoot Sheet

Objective. Standard Magnetic Resonance Imaging (MRI) reconstruction pipelines discard phase information captured during acquisition, despite evidence that it encodes tissue properties relevant to tumor diagnosis. Current machine learning…

Image and Video Processing · Electrical Eng. & Systems 2026-04-17 Marco Schlimbach , Moritz Rempe , Jessica Mnischek , Lukas T. Rotkopf , Jens Weingarten , Jens Kleesiek , Kevin Kröninger

Data-driven cell tracking and segmentation methods in biomedical imaging require diverse and information-rich training data. In cases where the number of training samples is limited, synthetic computer-generated data sets can be used to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 David Wiesner , Julian Suk , Sven Dummer , Tereza Nečasová , Vladimír Ulman , David Svoboda , Jelmer M. Wolterink

Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…

Generative AI models hold great potential in creating synthetic brain MRIs that advance neuroimaging studies by, for example, enriching data diversity. However, the mainstay of AI research only focuses on optimizing the visual quality (such…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Wei Peng , Tomas Bosschieter , Jiahong Ouyang , Robert Paul , Ehsan Adeli , Qingyu Zhao , Kilian M. Pohl

We introduce GEM3D -- a new deep, topology-aware generative model of 3D shapes. The key ingredient of our method is a neural skeleton-based representation encoding information on both shape topology and geometry. Through a denoising…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Dmitry Petrov , Pradyumn Goyal , Vikas Thamizharasan , Vladimir G. Kim , Matheus Gadelha , Melinos Averkiou , Siddhartha Chaudhuri , Evangelos Kalogerakis

We present a computational method for real-time, patient-specific simulation of 2D ultrasound (US) images. The method uses a large number of tracked ultrasound images to learn a function that maps position and orientation of the transducer…

Image and Video Processing · Electrical Eng. & Systems 2020-05-12 Cesare Magnetti , Veronika Zimmer , Nooshin Ghavami , Emily Skelton , Jacqueline Matthew , Karen Lloyd , Jo Hajnal , Julia A. Schnabel , Alberto Gomez

Recently, it has become progressively more evident that classic diagnostic labels are unable to reliably describe the complexity and variability of several clinical phenotypes. This is particularly true for a broad range of neuropsychiatric…

Machine Learning · Computer Science 2024-02-28 Giovanna Maria Dimitri , Simeon Spasov , Andrea Duggento , Luca Passamonti , Pietro Li`o , Nicola Toschi

3D brain MRI studies often examine subtle morphometric differences between cohorts that are hard to detect visually. Given the high cost of MRI acquisition, these studies could greatly benefit from image syntheses, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Binxu Li , Wei Peng , Mingjie Li , Ehsan Adeli , Kilian M. Pohl

Ultrasound b-mode imaging is a qualitative approach and diagnostic quality strongly depends on operators' training and experience. Quantitative approaches can provide information about tissue properties; therefore, can be used for…

Image and Video Processing · Electrical Eng. & Systems 2023-11-23 Farnaz Khun Jush , Markus Biele , Peter M. Dueppenbecker , Andreas Maier

3D generative modeling is accelerating as the technology allowing the capture of geometric data is developing. However, the acquired data is often inconsistent, resulting in unregistered meshes or point clouds. Many generative learning…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Thomas Besnier , Sylvain Arguillère , Emery Pierson , Mohamed Daoudi

Rapid advancements in medical image segmentation performance have been significantly driven by the development of Convolutional Neural Networks (CNNs) and Vision Transformers (ViTs). These models follow the discriminative pixel-wise…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Jiayu Huo , Xi Ouyang , Sébastien Ourselin , Rachel Sparks

3D ultrasound delivers high-resolution, real-time images of soft tissues, which is essential for pain research. However, manually distinguishing various tissues for quantitative analysis is labor-intensive. To streamline this process, we…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Zixue Zeng , Xiaoyan Zhao , Matthew Cartier , Xin Meng , Jiantao Pu

Real-world settings often do not allow acquisition of high-resolution volumetric images for accurate morphological assessment and diagnostic. In clinical practice it is frequently common to acquire only sparse data (e.g. individual slices)…

Image and Video Processing · Electrical Eng. & Systems 2019-08-30 Benjamin Hou , Athanasios Vlontzos , Amir Alansary , Daniel Rueckert , Bernhard Kainz
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