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Related papers: Generative Medical Event Models Improve with Scale

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We introduce a framework for optimizing domain-specific dataset construction in foundation model training. Specifically, we seek a cost-efficient way to estimate the quality of data sources (e.g. synthetically generated or filtered web…

In application domains such as healthcare, we want accurate predictive models that are also causally interpretable. In pursuit of such models, we propose a causal regularizer to steer predictive models towards causally-interpretable…

Machine Learning · Computer Science 2017-02-24 Mohammad Taha Bahadori , Krzysztof Chalupka , Edward Choi , Robert Chen , Walter F. Stewart , Jimeng Sun

Although understanding and characterizing causal effects have become essential in observational studies, it is challenging when the confounders are high-dimensional. In this article, we develop a general framework $\textit{CausalEGM}$ for…

Machine Learning · Statistics 2023-03-20 Qiao Liu , Zhongren Chen , Wing Hung Wong

The advent of Large Language Models (LLMs) has ushered in a new era for design science in Information Systems, demanding a paradigm shift in tailoring LLMs design for business contexts. We propose and test a novel framework to customize…

Computers and Society · Computer Science 2024-05-15 Wen Wang , Zhenyue Zhao , Tianshu Sun

Large Language Models (LLMs) have shown impressive potential to simulate human behavior. We identify a fundamental challenge in using them to simulate experiments: when LLM-simulated subjects are blind to the experimental design (as is…

Artificial Intelligence · Computer Science 2025-11-25 George Gui , Olivier Toubia

User event modeling plays a central role in many machine learning applications, with use cases spanning e-commerce, social media, finance, cybersecurity, and other domains. User events can be broadly categorized into personal events, which…

Machine Learning · Computer Science 2025-11-07 Rizal Fathony , Igor Melnyk , Owen Reinert , Nam H. Nguyen , Daniele Rosa , C. Bayan Bruss

While spatio-temporal Graph Neural Networks (GNNs) excel at modeling recurring traffic patterns, their reliability plummets during non-recurring events like accidents. This failure occurs because GNNs are fundamentally correlational models,…

Artificial Intelligence · Computer Science 2025-11-18 Luyao Niu , Zepu Wang , Shuyi Guan , Yang Liu , Peng Sun

Trace clustering has increasingly been applied to find homogenous process executions. However, current techniques have difficulties in finding a meaningful and insightful clustering of patients on the basis of healthcare data. The resulting…

Databases · Computer Science 2020-01-13 Xixi Lu , Seyed Amin Tabatabaei , Mark Hoogendoorn , Hajo A. Reijers

Deep learning (DL) creates impactful advances following a virtuous recipe: model architecture search, creating large training data sets, and scaling computation. It is widely believed that growing training sets and models should improve…

A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for…

Phenotypic characterization is essential for understanding heterogeneity in chronic diseases and for guiding personalized interventions. Long COVID, a complex and persistent condition, yet its clinical subphenotypes remain poorly…

Machine Learning · Computer Science 2026-03-20 Jing Wang , Jie Shen , Amar Sra , Qiaomin Xie , Jeremy C Weiss

Electronic Health Records (EHRs) contain rich temporal dynamics that conventional encoding approaches fail to adequately capture. While Large Language Models (LLMs) show promise for EHR modeling, they struggle to reason about sequential…

Artificial Intelligence · Computer Science 2025-10-01 Zekai Chen , Arda Pekis , Kevin Brown

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

Medical report generation demands automatic creation of coherent and precise descriptions for medical images. However, the scarcity of labelled medical image-report pairs poses formidable challenges in developing large-scale neural networks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-08 Shibin Wu , Bang Yang , Zhiyu Ye , Haoqian Wang , Hairong Zheng , Tong Zhang

Foundation models have achieved remarkable success across various domains, yet their adoption in healthcare remains limited. While significant advances have been made in medical imaging, genetic biomarkers, and time series from electronic…

Every year, millions of patients pass through emergency departments and intensive care units, where clinicians must make high-stakes decisions under time pressure and uncertainty. Machine learning could support prediction of deterioration,…

Machine Learning · Computer Science 2026-05-27 Yusuf Brima , Marcellin Atemkeng

Data scarcity is a common obstacle in medical research due to the high costs associated with data collection and the complexity of gaining access to and utilizing data. Synthesizing health data may provide an efficient and cost-effective…

Machine Learning · Computer Science 2023-08-01 Arinbjörn Kolbeinsson , Luca Foschini

Multiscale models allow for the treatment of complex phenomena involving different scales, such as remodeling and growth of tissues, muscular activation, and cardiac electrophysiology. Numerous numerical approaches have been developed to…

Numerical Analysis · Mathematics 2018-06-28 Marco Favino , Alessio Quaglino , Sonia Pozzi , Rolf Krause , Igor Pivkin

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

From simulating galaxy formation to viral transmission in a pandemic, scientific models play a pivotal role in developing scientific theories and supporting government policy decisions that affect us all. Given these critical applications,…

Software Engineering · Computer Science 2023-07-03 Andrew G. Clark , Michael Foster , Benedikt Prifling , Neil Walkinshaw , Robert M. Hierons , Volker Schmidt , Robert D. Turner
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