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Hypoglycemia is a severe condition of decreased blood glucose, specifically below 70 mg/dL (3.9 mmol/L). This condition can often be asymptomatic and challenging to predict in individuals with type 1 diabetes (T1D). Research on hypoglycemic…

Quantitative Methods · Quantitative Biology 2026-03-24 Vaibhav Gupta , Florian Grensing , Beyza Cinar , Louisa van den Boom , Maria Maleshkova

Effective postprandial glucose control is important to glucose management for subjects with diabetes mellitus. In this work, a data-driven meal bolus decision method is proposed without the need of subject-specific glucose management…

Systems and Control · Electrical Eng. & Systems 2021-01-21 Deheng Cai , Wei Liu , Linong Ji , Dawei Shi

Accurate blood glucose prediction can enable novel interventions for type 1 diabetes treatment, including personalized insulin and dietary adjustments. Although recent advances in transformer-based architectures have demonstrated the power…

Quantitative Methods · Quantitative Biology 2025-05-15 Meryem Altin Karagoz , Marc D. Breton , Anas El Fathi

Purpose: Understanding how the pancreas changes is critical for detecting deviations in type 2 diabetes and other pancreatic disease. We measure pancreas size and shape using morphological measurements from ages 0 to 90. Our goals are to 1)…

Diabetes is a chronicle disease where the body of a human is irregular to dissolve the blood glucose properly. The diabetes is due to lack of insulin in human body. The continuous monitoring of blood glucose is main important aspect for…

Medical Physics · Physics 2021-06-10 Prateek Jain , Amit M. Joshi , Saraju Mohanty

Research in diabetes, especially when it comes to building data-driven models to forecast future glucose values, is hindered by the sensitive nature of the data. Because researchers do not share the same data between studies, progress is…

Quantitative Methods · Quantitative Biology 2020-09-10 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Ischemic heart disease (IHD), particularly in its chronic stable form, is a subtle pathology due to its silent behavior before developing in unstable angina, myocardial infarction or sudden cardiac death. Machine learning techniques applied…

Signal Processing · Electrical Eng. & Systems 2020-11-20 Giulia Silveri , Marco Merlo , Luca Restivo , Gianfranco Sinagra , Agostino Accardo

The adoption of deep learning in healthcare is hindered by their "black box" nature. In this paper, we explore the RETAIN architecture for the task of glusose forecasting for diabetic people. By using a two-level attention mechanism, the…

Machine Learning · Computer Science 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Precise and timely forecasting of blood glucose levels is essential for effective diabetes management. While extensive research has been conducted on Type 1 diabetes mellitus, Type 2 diabetes mellitus (T2DM) presents unique challenges due…

Computational Engineering, Finance, and Science · Computer Science 2024-09-12 Yuyang Sun , Panagiotis Kosmas

Clinical time-series forecasting is increasingly studied for decision support, yet standard aggregate metrics can obscure whether a model is actually useful for the task it is meant to serve. In safety-critical settings, low average error…

Machine Learning · Computer Science 2026-05-04 Alireza Namazi , Heman Shakeri

In the UK, approximately 400,000 people with type 1 diabetes (T1D) rely on insulin delivery due to insufficient pancreatic insulin production. Managing blood glucose (BG) levels is crucial, with continuous glucose monitoring (CGM) playing a…

Machine Learning · Computer Science 2023-12-21 Chengzhe Piao , Ken Li

In the context of time-series forecasting, we propose a LSTM-based recurrent neural network architecture and loss function that enhance the stability of the predictions. In particular, the loss function penalizes the model, not only on the…

Signal Processing · Electrical Eng. & Systems 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Precise glucose level monitoring is critical for people with diabetes to avoid serious complications. While there are several methods for continuous glucose level monitoring, research on maintenance devices is limited. To mitigate the gap,…

Machine Learning · Computer Science 2024-06-10 Azmine Toushik Wasi

Diabetes is a chronic metabolic disorder characterized by persistently high blood glucose levels (BGLs), leading to severe complications such as cardiovascular disease, neuropathy, and retinopathy. Predicting BGLs enables patients to…

Daytime hypoglycemia should be accurately predicted to achieve normoglycemia and to avoid disastrous situations. Hypoglycemia, an abnormally low blood glucose level, is divided into daytime hypoglycemia and nocturnal hypoglycemia. Many…

Machine Learning · Statistics 2017-05-01 Miyeon Jung , You-Bin Lee , Sang-Man Jin , Sung-Min Park

Self-monitoring of blood glucose (SMBG) and continuous glucose monitoring (CGM) are commonly used by type 1 diabetes (T1D) patients to measure glucose concentrations. The proposed adaptive basal-bolus algorithm (ABBA) supports inputs from…

Systems and Control · Electrical Eng. & Systems 2024-12-20 Qingnan Sun , Marko V. Jankovic , João Budzinski , Brett Moore , Peter Diem , Christoph Stettler , Stavroula G. Mougiakakou

This article compares ten recently proposed neural networks and proposes two ensemble neural network-based models for blood glucose prediction. All of them are tested under the same dataset, preprocessing workflow, and tools using the…

Quantitative Methods · Quantitative Biology 2021-09-07 Felix Tena , Oscar Garnica , Juan Lanchares , J. Ignacio Hidalgo

People with diabetes must carefully monitor their blood glucose levels, especially after eating. Blood glucose regulation requires a proper combination of food intake and insulin boluses. Glucose prediction is vital to avoid dangerous…

Machine Learning · Computer Science 2023-07-06 Daniel Parra , David Joedicke , J. Manuel Velasco , Gabriel Kronberger , J. Ignacio Hidalgo

To best of the authors knowledge, this article presents the first-ever non-invasive glucometer that takes into account serum glucose for high accuracy. In case of blood glucose measurement, serum glucose value has always been considered…

Signal Processing · Electrical Eng. & Systems 2021-06-28 Prateek Jain , Amit M Joshi , Navneet Agrawal , Saraju Mohanty

We develop a new model of insulin-glucose dynamics for forecasting blood glucose in type 1 diabetics. We augment an existing biomedical model by introducing time-varying dynamics driven by a machine learning sequence model. Our model…

Machine Learning · Statistics 2020-08-10 Andrew C. Miller , Nicholas J. Foti , Emily Fox