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We introduce the delta-homology model of memory, a unified framework in which recall, learning, and prediction emerge from cycle closure, the completion of topologically constrained trajectories within the brain's latent manifold. A…

Machine Learning · Computer Science 2025-10-21 Xin Li

We propose a formal foundation for cognition rooted in algebraic topology, built on a Homological Parity Principle. This posits that even-dimensional homology represents stable Structure/Context (e.g., generative models), while…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Xin Li

Sequence learning, prediction and replay have been proposed to constitute the universal computations performed by the neocortex. The Hierarchical Temporal Memory (HTM) algorithm realizes these forms of computation. It learns sequences in an…

Neurons and Cognition · Quantitative Biology 2022-07-21 Younes Bouhadjar , Dirk J. Wouters , Markus Diesmann , Tom Tetzlaff

Contemporary ML separates the static structure of parameters from the dynamic flow of inference, yielding systems that lack the sample efficiency and thermodynamic frugality of biological cognition. In this theoretical work, we propose…

Machine Learning · Computer Science 2025-12-09 Xin Li

In this article, we introduce a Topological Data Analysis (TDA) pipeline for neural spike train data. Understanding how the brain transforms sensory information into perception and behavior requires analyzing coordinated neural population…

Methodology · Statistics 2025-12-10 Cagatay Ayhan , Audrey N. Nash , Roberto Vincis , Martin Bauer , Richard Bertram , Tom Needham

We present a topological framework for analysing neural time series that integrates Transfer Entropy (TE) with directed Persistent Homology (PH) to characterize information flow in spiking neural systems. TE quantifies directional influence…

Neurons and Cognition · Quantitative Biology 2025-08-27 Dylan Peek , Siddharth Pritam , Matthew P. Skerritt , Stephan Chalup

Topological techniques have become a popular tool for studying information flows in neural networks. In particular, simplicial homology theory is used to analyze how cognitive representations of space emerge from large conglomerates of…

Neurons and Cognition · Quantitative Biology 2025-02-19 Andrey Babichev , Vladimir Vashin , Yuri Dabaghian

We propose an information-topological framework in which cycle closure is the fundamental mechanism of memory and consciousness. Memory is not a static store but the ability to re-enter latent cycles in neural state space, with invariant…

Neural and Evolutionary Computing · Computer Science 2025-09-29 Xin Li

This paper introduces a unifying framework that links the Context-Content Uncertainty Principle (CCUP) with optimal transport (OT) via primal-dual inference. We propose that cognitive representations are not static encodings but active dual…

Neurons and Cognition · Quantitative Biology 2025-06-19 Xin Li

This paper presents a mathematically rigorous framework for brain-inspired representation learning founded on the interplay between persistent topological structures and cohomological flows. Neural computation is reformulated as the…

Machine Learning · Computer Science 2025-12-10 Preksha Girish , Rachana Mysore , Mahanthesha U , Shrey Kumar , Shipra Prashant

Biological intelligence emerges from substrates that are slow, noisy, and energetically constrained, yet it performs rapid and coherent inference in open-ended environments. Classical computational theories, built around vector-space…

Neurons and Cognition · Quantitative Biology 2026-05-12 Xin Li

We introduce \emph{Information Topology}: a framework that unifies information theory and algebraic topology by treating \emph{cycle closure} as the primitive operation of inference. The starting point is the \emph{dot-cycle dichotomy},…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Xin Li

We introduce a novel approach to endowing neural networks with emergent, long-term, large-scale memory. Distinct from strategies that connect neural networks to external memory banks via intricately crafted controllers and hand-designed…

Machine Learning · Computer Science 2020-08-18 Tri Huynh , Michael Maire , Matthew R. Walter

Just as the arrow of time structures physics, the arrow of inference organizes cognition, directing the flow of information in perception, action, and memory. The Context-Content Uncertainty Principle (CCUP) formalizes this asymmetry,…

Neurons and Cognition · Quantitative Biology 2025-06-12 Xin Li

The spiking activity of the hippocampal place cells plays a key role in producing and sustaining an internalized representation of the ambient space---a cognitive map. These cells do not only exhibit location-specific spiking during…

Neurons and Cognition · Quantitative Biology 2018-11-05 Andrey Babichev , Dmitriy Morozov , Yuri Dabaghian

The effectiveness of Spatio-temporal Graph Neural Networks (STGNNs) in time-series applications is often limited by their dependence on fixed, hand-crafted input graph structures. Motivated by insights from the Topological Data Analysis…

Machine Learning · Computer Science 2025-03-20 Viet The Nguyen , Duy Anh Pham , An Thai Le , Jans Peter , Gunther Gust

Memory consolidation, the process by which transient experiences are transformed into stable, structured representations, is a foundational organizing principle in the human brain, yet it remains largely unexplored as a design principle for…

Computation and Language · Computer Science 2026-05-12 Lungchuan Chen

The spiking activity of principal cells in mammalian hippocampus encodes an internalized neuronal representation of the ambient space---a cognitive map. Once learned, such a map enables the animal to navigate a given environment for a long…

Neurons and Cognition · Quantitative Biology 2017-10-10 Andrey Babichev , Dmitriy Morozov , Yuri Dabaghian

Working memory is a cognitive function involving the storage and manipulation of latent information over brief intervals of time, thus making it crucial for context-dependent computation. Here, we use a top-down modeling approach to examine…

Neurons and Cognition · Quantitative Biology 2021-11-17 Elham Ghazizadeh , ShiNung Ching

Associative memory architectures such as the Hopfield network have long been important conceptual and theoretical models for neuroscience and artificial intelligence. However, translating these abstract models into spiking neural networks…

Neurons and Cognition · Quantitative Biology 2025-07-02 William F. Podlaski , Christian K. Machens
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