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High-dimensional data acquired from biological experiments such as next generation sequencing are subject to a number of confounding effects. These effects include both technical effects, such as variation across batches from instrument…
Instance contrast for unsupervised representation learning has achieved great success in recent years. In this work, we explore the idea of instance contrastive learning in unsupervised domain adaptation (UDA) and propose a novel Category…
Recent multimodal models such as Contrastive Language-Image Pre-training (CLIP) have shown remarkable ability to align visual and linguistic representations. However, domains where small visual differences carry large semantic significance,…
Unsupervised image-to-image translation tasks aim to find a mapping between a source domain X and a target domain Y from unpaired training data. Contrastive learning for Unpaired image-to-image Translation (CUT) yields state-of-the-art…
Factor analysis and principal component analysis (PCA) are used in many application areas. The first step, choosing the number of components, remains a serious challenge. Our work proposes improved methods for this important problem. One of…
Efficiently utilizing discriminative features is crucial for convolutional neural networks to achieve remarkable performance in medical image segmentation and is also important for model generalization across multiple domains, where letting…
Estimating an individual's potential response to interventions from observational data is of high practical relevance for many domains, such as healthcare, public policy or economics. In this setting, it is often the case that combinations…
Image captioning, a popular topic in computer vision, has achieved substantial progress in recent years. However, the distinctiveness of natural descriptions is often overlooked in previous work. It is closely related to the quality of…
Cross-modal contrastive distillation has recently been explored for learning effective 3D representations. However, existing methods focus primarily on modality-shared features, neglecting the modality-specific features during the…
Unsupervised disentanglement of content and transformation is significantly important for analyzing shape-focused scientific image datasets, given their efficacy in solving downstream image-based shape-analyses tasks. The existing relevant…
Principal component analysis (PCA) is a widely used unsupervised dimensionality reduction technique in machine learning, applied across various fields such as bioinformatics, computer vision and finance. However, when the response variables…
Cluster interpretation after dimensionality reduction (DR) is a ubiquitous part of exploring multidimensional datasets. DR results are frequently represented by scatterplots, where spatial proximity encodes similarity among data samples. In…
Medical image segmentation is a crucial task in medical image analysis, but it can be very challenging especially when there are less labeled data but with large unlabeled data. Contrastive learning has proven to be effective for medical…
In this work, we propose a new data visualization and clustering technique for discovering discriminative structures in high-dimensional data. This technique, referred to as cPCA++, utilizes the fact that the interesting features of a…
The increasing availability of multi-sensor data sparks wide interest in multimodal self-supervised learning. However, most existing approaches learn only common representations across modalities while ignoring intra-modal training and…
As one of the most effective self-supervised representation learning methods, contrastive learning (CL) relies on multiple negative pairs to contrast against each positive pair. In the standard practice of contrastive learning, data…
This paper presents a novel positive and negative set selection strategy for contrastive learning of medical images based on labels that can be extracted from clinical data. In the medical field, there exists a variety of labels for data…
Unsupervised learning techniques in computer vision often require learning latent representations, such as low-dimensional linear and non-linear subspaces. Noise and outliers in the data can frustrate these approaches by obscuring the…
Principal component analysis (PCA) is often used for analyzing data in the most diverse areas. In this work, we report an integrated approach to several theoretical and practical aspects of PCA. We start by providing, in an intuitive and…
Motivation: Although principal component analysis is frequently applied to reduce the dimensionality of matrix data, the method is sensitive to noise and bias and has difficulty with comparability and interpretation. These issues are…