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Contrastive dimension reduction (CDR) methods aim to extract signal unique to or enriched in a treatment (foreground) group relative to a control (background) group. This setting arises in many scientific domains, such as genomics, imaging,…

Methodology · Statistics 2025-10-15 Sam Hawke , Eric Zhang , Jiawen Chen , Didong Li

Capturing patterns of variation present in a dataset is important in exploratory data analysis and unsupervised learning. Contrastive dimension reduction methods, such as contrastive principal component analysis (cPCA), find patterns unique…

Machine Learning · Computer Science 2021-04-19 Robin Tu , Alexander H. Foss , Sihai D. Zhao

We present a new technique called contrastive principal component analysis (cPCA) that is designed to discover low-dimensional structure that is unique to a dataset, or enriched in one dataset relative to other data. The technique is a…

Machine Learning · Statistics 2017-11-23 Abubakar Abid , Martin J. Zhang , Vivek K. Bagaria , James Zou

Dimensionality reduction (DR) is frequently used for analyzing and visualizing high-dimensional data as it provides a good first glance of the data. However, to interpret the DR result for gaining useful insights from the data, it would…

Machine Learning · Computer Science 2019-10-16 Takanori Fujiwara , Oh-Hyun Kwon , Kwan-Liu Ma

Dimension reduction is useful for exploratory data analysis. In many applications, it is of interest to discover variation that is enriched in a "foreground" dataset relative to a "background" dataset. Recently, contrastive principal…

Methodology · Statistics 2021-05-04 Didong Li , Andrew Jones , Barbara Engelhardt

Contrastive dimension reduction methods have been developed for case-control study data to identify variation that is enriched in the foreground (case) data X relative to the background (control) data Y. Here, we develop contrastive…

Methodology · Statistics 2024-01-09 Boyang Zhang , Sarah Nyquist , Andrew Jones , Barbara E. Engelhardt , Didong Li

Principal component analysis (PCA) is widely used for feature extraction and dimensionality reduction, with documented merits in diverse tasks involving high-dimensional data. Standard PCA copes with one dataset at a time, but it is…

Machine Learning · Computer Science 2019-01-30 Jia Chen , Gang Wang , Georgios B. Giannakis

Supervised dimension reduction (SDR) has been a topic of growing interest in data science, as it enables the reduction of high-dimensional covariates while preserving the functional relation with certain response variables of interest.…

Machine Learning · Statistics 2023-05-23 Sam Hawke , Hengrui Luo , Didong Li

Contrastive analysis (CA) refers to the exploration of variations uniquely enriched in a target dataset as compared to a corresponding background dataset generated from sources of variation that are irrelevant to a given task. For example,…

Machine Learning · Computer Science 2023-10-31 Ethan Weinberger , Ian Covert , Su-In Lee

In recent years, there has been growing interest in jointly analyzing a foreground dataset, representing an experimental group, and a background dataset, representing a control group. The goal of such contrastive investigations is to…

Statistics Theory · Mathematics 2026-01-27 Kexin Wang , Aida Maraj , Anna Seigal

Principal component analysis (PCA) is a well-known linear dimension-reduction method that has been widely used in data analysis and modeling. It is an unsupervised learning technique that identifies a suitable linear subspace for the input…

Machine Learning · Statistics 2021-09-10 Shaojie Xu , Joel Vaughan , Jie Chen , Agus Sudjianto , Vijayan Nair

Medical image segmentation plays an important role in clinical decision making, treatment planning, and disease tracking. However, it still faces two major challenges. On the one hand, there is often a ``soft boundary'' between foreground…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Mengqi Lei , Haochen Wu , Xinhua Lv , Xin Wang

Contrastive learning demonstrates great promise for representation learning. Data augmentations play a critical role in contrastive learning by providing informative views of the data without necessitating explicit labels. Nonetheless, the…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Zihu Wang , Yu Wang , Zhuotong Chen , Hanbin Hu , Peng Li

Contrastive Analysis is a sub-field of Representation Learning that aims at separating common factors of variation between two datasets, a background (i.e., healthy subjects) and a target (i.e., diseased subjects), from the salient factors…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Robin Louiset , Edouard Duchesnay , Antoine Grigis , Pietro Gori

Estimating causal effects is vital for decision making. In standard causal effect estimation, treatments are usually binary- or continuous-valued. However, in many important real-world settings, treatments can be structured,…

Machine Learning · Statistics 2024-12-02 Oriol Corcoll Andreu , Athanasios Vlontzos , Michael O'Riordan , Ciaran M. Gilligan-Lee

Self-supervised instance discrimination is an effective contrastive pretext task to learn feature representations and address limited medical image annotations. The idea is to make features of transformed versions of the same images similar…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Yejia Zhang , Xinrong Hu , Nishchal Sapkota , Yiyu Shi , Danny Z. Chen

Clustering continues to be a significant and challenging task. Recent studies have demonstrated impressive results by applying clustering to feature representations acquired through self-supervised learning, particularly on small datasets.…

Machine Learning · Computer Science 2023-07-19 Fei Ding , Dan Zhang , Yin Yang , Venkat Krovi , Feng Luo

Visual contrastive learning aims to learn representations by contrasting similar (positive) and dissimilar (negative) pairs of data samples. The design of these pairs significantly impacts representation quality, training efficiency, and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Shasvat Desai , Debasmita Ghose , Deep Chakraborty

We introduce Cluster Contrast (CueCo), a novel approach to unsupervised visual representation learning that effectively combines the strengths of contrastive learning and clustering methods. Inspired by recent advancements, CueCo is…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Nikolaos Giakoumoglou , Tania Stathaki

This paper considers the use of Robust PCA in a CUR decomposition framework and applications thereof. Our main algorithms produce a robust version of column-row factorizations of matrices $\mathbf{D}=\mathbf{L}+\mathbf{S}$ where…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 HanQin Cai , Keaton Hamm , Longxiu Huang , Deanna Needell
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