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Adaptive deep brain stimulation (aDBS) has emerged as a promising treatment for Parkinson disease (PD). In aDBS, a surgically placed electrode sends dynamically altered stimuli to the brain based on neurophysiological feedback: an invasive…

Neurons and Cognition · Quantitative Biology 2025-05-16 Ekaterina Kuzmina , Dmitrii Kriukov , Mikhail Lebedev , Dmitry V. Dylov

Deep brain stimulation (DBS) is an established intervention for Parkinson's disease (PD), but conventional open-loop systems lack adaptability, are energy-inefficient due to continuous stimulation, and provide limited personalization to…

Machine Learning · Computer Science 2025-07-10 Harsh Ravivarapu , Gaurav Bagwe , Xiaoyong Yuan , Chunxiu Yu , Lan Zhang

Cortical oscillations, electrophysiological activity patterns, associated with cognitive functions and impaired in many psychiatric disorders can be observed in intracranial electroencephalography (iEEG). Direct cortical stimulation (DCS)…

Medical Physics · Physics 2018-11-22 Sankaraleengam Alagapan , Hae Won Shin , Flavio Frohlich , Hau-tieng Wu

Deep Brain Stimulation (DBS) stands as an effective intervention for alleviating the motor symptoms of Parkinson's disease (PD). Traditional commercial DBS devices are only able to deliver fixed-frequency periodic pulses to the basal…

Machine Learning · Computer Science 2024-03-12 Hao-Lun Hsu , Qitong Gao , Miroslav Pajic

Deep brain stimulation (DBS) has the potential to improve the quality of life of people with a variety of neurological diseases. A key challenge in DBS is in the placement of a stimulation electrode in the anatomical location that maximizes…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Camilo Bermudez , William Rodriguez , Yuankai Huo , Allison E. Hainline , Rui Li , Robert Shults , Pierre D. DHaese , Peter E. Konrad , Benoit M. Dawant , Bennett A. Landman

In-scanner motion degrades the quality of magnetic resonance imaging (MRI) thereby reducing its utility in the detection of clinically relevant abnormalities. We introduce a deep learning-based MRI artifact reduction model (DMAR) to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 Yijun Zhao , Jacek Ossowski , Xuming Wang , Shangjin Li , Orrin Devinsky , Samantha P. Martin , Heath R. Pardoe

Deep Brain Stimulation (DBS) is an effective treatment for Parkinson's disease, but conventional fixed-parameter stimulation can reduce battery life and cause side effects while failing to adapt to changing neural dynamics. Recent…

Decoding motor performance from brain signals offers promising avenues for adaptive deep brain stimulation (aDBS) for Parkinson's disease (PD). In a two-center cohort of 19 PD patients executing a drawing task, we decoded motor performance…

Epilepsy is the fourth most common neurological disorder and affects people of all ages worldwide. Deep Brain Stimulation (DBS) has emerged as an alternative treatment option when anti-epileptic drugs or resective surgery cannot lead to…

Image and Video Processing · Electrical Eng. & Systems 2022-01-27 Han Liu , Kathryn L. Holloway , Dario J. Englot , Benoit M. Dawant

This paper presents the results of our recent work on studying the effects of deep brain stimulation (DBS) and medication on the dynamics of brain local field potential (LFP) signals used for behavior analysis of patients with Parkinson s…

Neurons and Cognition · Quantitative Biology 2018-04-11 Hosein M. Golshan , Adam O. Hebb , Joshua Nedrud , Mohammad H. Mahoor

Deep brain stimulation (DBS) is a neurosurgical procedure successfully used to treat conditions such as Parkinson's disease. Electrostimulation, carried out by implanting electrodes into an identified focus in the brain, makes it possible…

Signal Processing · Electrical Eng. & Systems 2023-08-23 Arkadiusz Nowacki , Ewelina Kołpa , Mateusz Szychiewicz , Konrad Ciecierski

We present a nonlinear data-driven Model Predictive Control (MPC) algorithm for deep brain stimulation (DBS) for the treatment of Parkinson's disease (PD). Although DBS is typically implemented in open-loop, closed-loop DBS (CLDBS) uses the…

Optimization and Control · Mathematics 2025-09-09 Sebastian Steffen , Mark Cannon

Transcranial magnetic stimulation combined with electroencephalography (TMS-EEG) is widely used to study the reactivity and connectivity of brain regions for clinical or research purposes. The electromagnetic pulse of the TMS device…

Quantitative Methods · Quantitative Biology 2019-10-30 Panteleimon Vafeidis , Vasilios K. Kimiskidis , Dimitris Kugiumtzis

Diffusion-weighted MRI is nowadays performed routinely due to its prognostic ability, yet the quality of the scans are often unsatisfactory which can subsequently hamper the clinical utility. To overcome the limitations, here we propose a…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Hyungjin Chung , Jaehyun Kim , Jeong Hee Yoon , Jeong Min Lee , Jong Chul Ye

Three-dimensional coronary magnetic resonance angiography (CMRA) demands reconstruction algorithms that can significantly suppress the artifacts from a heavily undersampled acquisition. While unrolling-based deep reconstruction methods have…

Image and Video Processing · Electrical Eng. & Systems 2024-02-05 Zhihao Xue , Fan Yang , Juan Gao , Zhuo Chen , Hao Peng , Chao Zou , Hang Jin , Chenxi Hu

Metal artifact significantly degrades Computed Tomography (CT) image quality, impeding accurate clinical diagnosis. However, existing deep learning approaches, such as CNN and Transformer, often fail to explicitly capture the directional…

Image and Video Processing · Electrical Eng. & Systems 2026-02-09 Bowen Ning , Zekun Zhou , Xinyi Zhong , Zhongzhen Wang , HongXin Wu , HaiTao Wang , Liu Shi , Qiegen Liu

Deep Brain Stimulation (DBS) is effective in treating neurological disorders but involves invasive surgery. Non-invasive DBS aims to overcome surgical risks by means of externally applied electromagnetic fields. In this work, we present a…

Medical Physics · Physics 2026-02-24 Mika Söderström , Melker Carlsson , Patrik Nicolausson , Mariana Dalarsson

Lidar SLAM plays a significant role in mobile robot navigation and high-definition map construction. However, existing methods often face a trade-off between localization accuracy and system robustness in scenarios with a high proportion of…

Robotics · Computer Science 2025-12-02 Yongxin Shao , Aihong Tan , Binrui Wang , Yinlian Jin , Licong Guan , Peng Liao

Fast arbitrary neural style transfer has attracted widespread attention from academic, industrial and art communities due to its flexibility in enabling various applications. Existing solutions either attentively fuse deep style feature…

Computer Vision and Pattern Recognition · Computer Science 2021-08-12 Songhua Liu , Tianwei Lin , Dongliang He , Fu Li , Meiling Wang , Xin Li , Zhengxing Sun , Qian Li , Errui Ding

Deep Brain Stimulation (DBS) is a highly effective treatment for Parkinson's Disease (PD). Recent research uses reinforcement learning (RL) for DBS, with RL agents modulating the stimulation frequency and amplitude. But, these models rely…

Machine Learning · Computer Science 2025-10-07 Nicholas Carter , Arkaprava Gupta , Prateek Ganguli , Benedikt Dietrich , Vibhor Krishna , Samarjit Chakraborty
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