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Mental disorders may exhibit pathological brain rhythms and neurostimulation promises to alleviate of patients' symptoms by modifying these rhythms. Today, most neurostimulation schemes are open-loop, i.e. administer experimental…

Neurons and Cognition · Quantitative Biology 2023-03-21 Thomas Wahl , Michel Duprez , Axel Hutt

Over the past decade, there has been an unprecedented international focus on improved quality and availability of medical care, which has reignited interest in clinical automation and drawn researchers toward novel solutions in the field of…

Systems and Control · Electrical Eng. & Systems 2020-01-27 Mohammad Javad Khodaei , Nicholas Candelino , Amin Mehrvarz , Nader Jalili

The application of closed-loop approaches in systems neuroscience and therapeutic stimulation holds great promise for revolutionizing our understanding of the brain and for developing novel neuromodulation therapies to restore lost…

Signal Processing · Electrical Eng. & Systems 2021-10-12 Bingzhao Zhu , Uisub Shin , Mahsa Shoaran

Neural networks modularity is a major challenge for the development of control circuits of neural activity. Under physiological limitations, the accessible regions for external stimulation are possibly different from the functionally…

Neurons and Cognition · Quantitative Biology 2018-02-23 Hanna Keren , Johannes Partzsch , Shimon Marom , Christian Mayr

Mental disorders (MD) are among the top most demanding challenges in world-wide health. According to the World Health Organization, the burden of MDs continues to grow with significant impact on health and major social and human rights. A…

Neurons and Cognition · Quantitative Biology 2023-03-21 Thomas Wahl , Joséphine Riedinger , Michel Duprez , Axel Hutt

We propose the Riskman ontology and shapes for representing and analysing information about risk management for medical devices. Risk management is concerned with taking necessary precautions to ensure that a medical device does not cause…

Robots for physical Human-Robot Collaboration (pHRC) systems need to change their behavior and how they operate in consideration of several factors, such as the performance and intention of a human co-worker and the capabilities of…

Robotics · Computer Science 2023-10-03 Avinash Singh , Dikai Liu , Chin-Teng Lin

A new hybrid tracking controller for neuromuscular electrical stimulation is proposed. The control scheme uses sampled measurements and is designed by utilizing a numerical prediction of the state variables. The tracking error of the…

Optimization and Control · Mathematics 2013-10-08 Iasson Karafyllis , Michael Malisoff , Marcio de Queiroz , Miroslav Krstic

This paper develops a Closed-Loop Error Learning Control (CLELC) algorithm for feedback linearizable systems with experimental validation on a mobile robot. Traditional feedback and feedforward controllers are designed based on the nominal…

Robotics · Computer Science 2021-03-17 Erkan Kayacan

Closed-loop neurotechnology requires the capability to predict the state evolution and its regulation under (possibly) partial measurements. There is evidence that neurophysiological dynamics can be modeled by fractional-order dynamical…

Optimization and Control · Mathematics 2019-03-05 Sarthak Chatterjee , Orlando Romero , Sérgio Pequito

Neurostimulation technologies have seen a recent surge in interest from the neuroscience and controls communities alike due to their proven potential to treat conditions such as Parkinson's Disease, and depression. The provided stimulation…

Systems and Control · Electrical Eng. & Systems 2023-01-03 Gagan Acharya , Sebastian F. Ruf , Erfan Nozari

A novel perspective on the design of robust model predictive control (MPC) methods is presented, whereby closed-loop constraint satisfaction is ensured using recursive feasibility of the MPC optimization. Necessary and sufficient conditions…

Systems and Control · Electrical Eng. & Systems 2023-03-21 Anilkumar Parsi , Marcell Bartos , Amber Srivastava , Sebastien Gros , Roy S. Smith

Clinical guidance systems have been widely adopted to help medical staffs to avoid preventable medical errors such as delay in diagnosis, treatment or untended deviations from best practice guidelines. However, because patient condition…

Computers and Society · Computer Science 2016-10-24 Maryam Rahmaniheris , Yu Jiang , Lui Sha

Despite their success in massive engineering applications, deep neural networks are vulnerable to various perturbations due to their black-box nature. Recent study has shown that a deep neural network can misclassify the data even if the…

Machine Learning · Computer Science 2021-04-29 Zhuotong Chen , Qianxiao Li , Zheng Zhang

Objective: Closed-loop deep brain stimulation (DBS) may improve current clinical DBS treatment for neurological movement disorders, but control algorithms may perform differently across patients. New metrics are needed for comparing and…

Neurons and Cognition · Quantitative Biology 2016-05-31 Jeffrey Herron , Anca Velisar , Mahsa Malekmohammadi , Helen Bronte-Stewart , Howard Jay Chizeck

Living organisms interact with their surroundings in a closed-loop fashion, where sensory inputs dictate the initiation and termination of behaviours. Even simple animals are able to develop and execute complex plans, which has not yet been…

Robotics · Computer Science 2025-01-30 Giulia Lafratta , Bernd Porr , Christopher Chandler , Alice Miller

In recent years, the integration of prediction and planning through neural networks has received substantial attention. Despite extensive studies on it, there is a noticeable gap in understanding the operation of such models within a…

Robotics · Computer Science 2024-07-09 Jiayu Guo , Mingyue Feng , Pengfei Zhu , Chengjun Li , Jian Pu

Neuromodulation techniques have emerged as promising approaches for treating a wide range of neurological disorders, precisely delivering electrical stimulation to modulate abnormal neuronal activity. While leveraging the unique…

Sleep disorders have emerged as a critical global health issue, highlighting the urgent need for effective and widely accessible intervention technologies. Non-invasive brain stimulation has garnered attention as it enables direct or…

Human-Computer Interaction · Computer Science 2025-12-04 Guisong Liu , Jiansong Zhang , Yinpei Luo , Guoliang Wei , Shuqing Sun , Shiyang Deng , Pengfei Wei , Nanxi Chen

In this paper, a novel robust tracking control scheme for a general class of discrete-time nonlinear systems affected by unknown bounded uncertainty is presented. By solving a parameterized optimal tracking control problem subject to the…

Systems and Control · Electrical Eng. & Systems 2023-12-08 Alexandros Tanzanakis , John Lygeros
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