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A recurrent idea in the study of complex systems is that optimal information processing is to be found near bifurcation points or phase transitions. However, this heuristic hypothesis has few (if any) concrete realizations where a standard…

Neurons and Cognition · Quantitative Biology 2007-05-23 Osame Kinouchi , Mauro Copelli

The converters in an AC/DC grid form actuated boundaries between the AC and DC subgrids. We show how in both simple linear and balanced dq-frame models, the states on either side of these boundaries are coupled only by control inputs. This…

Optimization and Control · Mathematics 2023-07-20 Josh A. Taylor

Fission yeast G2/M transition is regulated by a biochemical reaction networks which contains four components: Cdc13, Cdc2, Wee1, and Cdc25. This circuit is characterized by the ultrasensitive responses of Wee1 or Cdc25 to Cdc13/Cdc2…

Molecular Networks · Quantitative Biology 2016-12-06 Teng Wang , Chenzi Jin , Fangting Li

Trigger waves are self-regenerating propagating fronts that emerge from the coupling of nonlinear reaction kinetics and diffusion. In cells, trigger waves coordinate large-scale processes such as mitotic entry and stress responses. Although…

Molecular Networks · Quantitative Biology 2026-03-12 Jianwei Li , Kai Meng , Xuewen Shen , Fangting Li

Deciphering the control principles of metabolism and its interaction with other cellular functions is central to biomedicine and biotechnology. Yet, understanding the efficient control of metabolic fluxes remains elusive for large-scale…

Molecular Networks · Quantitative Biology 2015-09-04 Georg Basler , Zoran Nikoloski , Abdelhalim Larhlimi , Albert-László Barabási , Yang-Yu Liu

Many cellular networks rely on the regulated transport of their components to transduce extracellular information into precise intracellular signals. The dynamics of these networks is typically described in terms of compartmentalized…

Subcellular Processes · Quantitative Biology 2011-11-18 Jose M. G. Vilar , Leonor Saiz

Phase separation and transitions among different molecular states are ubiquitous in living cells. Such transitions can be governed by local equilibrium thermodynamics or by active processes controlled by biological fuel. It remains largely…

Biological Physics · Physics 2021-11-24 G. Bartolucci , O. Adame-Arana , X. Zhao , C. A. Weber

Changes in a cell's external or internal conditions are usually reflected in the concentrations of the relevant transcription factors. These proteins in turn modulate the expression levels of the genes under their control and sometimes need…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , Curtis G Callan , William Bialek

We present a novel, integrated control framework designed to achieve seamless transitions among a spectrum of inverter operation modes. The operation spectrum includes grid-forming (GFM), grid-following (GFL), static synchronous compensator…

Systems and Control · Electrical Eng. & Systems 2024-10-14 Alireza Askarian , Jaesang Park , Srinivasa Salapaka

We propose an information-theoretic framework for analyzing control systems based on the close relationship of controllers to communication channels. A communication channel takes an input state and transforms it into an output state. A…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Hugo Touchette , Seth Lloyd

Exploring nonlinear chemical dynamic systems for information processing has emerged as a frontier in chemical and computational research, seeking to replicate the brain's neuromorphic and dynamic functionalities. We have extensively…

Chemical Physics · Physics 2026-05-19 Zheyang Li , Xi Yu

Intracellular signaling often arises from ligand-induced oligomerization of cell surface receptors. This oligomerization or clustering process is fundamentally a cooperative behavior between near-neighbor receptor molecules; the properties…

Soft Condensed Matter · Physics 2009-10-31 Chinlin Guo , Herbert Levine

Input feed-forward output feedback passive (IF-OFP) systems define a great number of dynamical systems. In this report, we show that dissipativity and passivity-based control combined with event-triggered networked control systems (NCS)…

Optimization and Control · Mathematics 2016-07-05 Arash Rahnama , Meng Xia , Panos J. Antsaklis

Receptor-induced apoptosis is a complex signal transduction pathway involving numerous protein/protein interactions and post-transcriptional modifications. The response to death receptor stimulation varies significantly from one cell line…

Quantitative Methods · Quantitative Biology 2017-12-20 François Bertaux , Dirk Drasdo , Gregory Batt

Based on the phosphorelay kinetics operative within BvgAS two component system we propose a mathematical framework for signal transduction and gene regulation of phenotypic phases in Bordetella pertussis. The proposed model identifies a…

Molecular Networks · Quantitative Biology 2012-11-06 Arnab Bandyopadhyay , Suman K. Banik

To maintain homeostasis, living cells process information with networks of interacting molecules. Traditional models for cellular information processing have focused on networks of chemical reactions between molecules. Here, we describe how…

Biological Physics · Physics 2025-08-01 Arvind Murugan , David Zwicker , Charlotta Lorenz , Eric R. Dufresne

Agglomeration, adsorption, and extraction in dispersed multiphase systems are ubiquitously encountered in biological systems, energy industry, and medical science. In this work, a novel lattice model is extended to the three-component…

Statistical Mechanics · Physics 2022-10-12 Yiran Li , Yunfan Huang , Xukang Lu , Moran Wang

Membrane transporters contribute to the regulation of the internal environment of cells by translocating substrates across cell membranes. Like all physical systems, the behaviour of membrane transporters is constrained by the laws of…

Biomolecules · Quantitative Biology 2023-07-19 Michael Pan , Peter J. Gawthrop , Kenneth Tran , Joseph Cursons , Edmund J. Crampin

We consider the model of the optical switching center - a system with the following properties: It has two (or more) metastable states |1>, |2>, separated by a potential barrier U; it can switch from one state to another by absorbing the…

Strongly Correlated Electrons · Physics 2009-11-11 E. V. Zenkov

In this work, we investigate grid-forming control for power systems containing three-phase and single-phase converters connected to unbalanced distribution and transmission networks, investigate self-balancing between single-phase…

Systems and Control · Electrical Eng. & Systems 2022-11-15 Shahin S. Nudehi , Dominic Groß