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Related papers: Performance of GPT-5 in Brain Tumor MRI Reasoning

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Radiology, radiation oncology, and medical physics require decision-making that integrates medical images, textual reports, and quantitative data under high-stakes conditions. With the introduction of GPT-5, it is critical to assess whether…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Mingzhe Hu , Zach Eidex , Shansong Wang , Mojtaba Safari , Qiang Li , Xiaofeng Yang

Mammogram visual question answering (VQA) integrates image interpretation with clinical reasoning and has potential to support breast cancer screening. We systematically evaluated the GPT-5 family and GPT-4o model on four public mammography…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Qiang Li , Shansong Wang , Mingzhe Hu , Mojtaba Safari , Zachary Eidex , Xiaofeng Yang

Recent advances in large language models (LLMs) have enabled general-purpose systems to perform increasingly complex domain-specific reasoning without extensive fine-tuning. In the medical domain, decision-making often requires integrating…

Computation and Language · Computer Science 2025-08-14 Shansong Wang , Mingzhe Hu , Qiang Li , Mojtaba Safari , Xiaofeng Yang

Introduction: Large language models (LLM) have shown great potential in clinical decision support. GPT-5 is a novel LLM system that has been specifically marketed towards oncology use. Methods: Performance was assessed using two…

The transition from task-specific artificial intelligence toward general-purpose foundation models raises fundamental questions about their capacity to support the integrated reasoning required in clinical medicine, where diagnosis demands…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Alexandru Florea , Shansong Wang , Mingzhe Hu , Qiang Li , Zach Eidex , Luke del Balzo , Mojtaba Safari , Xiaofeng Yang

Large language models (LLMs) such as GPT-5 integrate advanced reasoning capabilities that may improve performance on complex medical question-answering tasks. For this latest generation of reasoning models, the configurations that maximize…

Brain tumor diagnosis is largely dependent on Magnetic Resonance Imaging (MRI) evaluation, which requires radiologists to synthesize thousands of images across multiple 3D sequences and longitudinal studies. This process requires advanced…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Shiv Ghosh , Junayd Lateef , Chih-Hua Liu , Yannan Yu , Andreas M. Rauschecker , Madhumita Sushil

Recent advances in multimodal large language models enable new possibilities for image-based decision support. However, their reliability and operational trade-offs in neuroimaging remain insufficiently understood. We present a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Katarina Trojachanec Dineva , Stefan Andonov , Ilinka Ivanoska , Ivan Kitanovski , Sasho Gramatikov , Tamara Kostova , Monika Simjanoska Misheva , Kostadin Mishev

Accurate brain tumor diagnosis requires models to not only detect lesions but also generate clinically interpretable reasoning grounded in imaging manifestations, yet existing public datasets remain limited in annotation richness and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Feng Guo , Jiaxiang Liu , Yang Li , Qianqian Shi , Mingkun Xu

This study deliberates on the application of advanced AI techniques for brain tumor classification through MRI, wherein the training includes the present best deep learning models to enhance diagnosis accuracy and the potential of usability…

This study presents a convolutional neural network (CNN)-based approach for the multi-class classification of brain tumors using magnetic resonance imaging (MRI) scans. We utilize a publicly available dataset containing MRI images…

Image and Video Processing · Electrical Eng. & Systems 2025-05-07 Natnael Alemayehu

The RSNA-MICCAI brain tumor radiogenomic classification challenge aimed to predict MGMT biomarker status in glioblastoma through binary classification on Multi parameter mpMRI scans: T1w, T1wCE, T2w and FLAIR. The dataset is splitted into…

Image and Video Processing · Electrical Eng. & Systems 2024-01-19 Amr Mohamed , Mahmoud Rabea , Aya Sameh , Ehab Kamal

Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Cecilia Diana-Albelda , Roberto Alcover-Couso , Álvaro García-Martín , Jesus Bescos , Marcos Escudero-Viñolo

MLLMs MLLMs are beginning to appear in clinical workflows, but their ability to perform complex medical reasoning remains unclear. We present Med-CMR, a fine-grained Medical Complex Multimodal Reasoning benchmark. Med-CMR distinguishes from…

Biomedical literature and clinical narratives pose multifaceted challenges for natural language understanding, from precise entity extraction and document synthesis to multi-step diagnostic reasoning. This study extends a unified benchmark…

Computation and Language · Computer Science 2025-10-24 Yu Hou , Zaifu Zhan , Min Zeng , Yifan Wu , Shuang Zhou , Rui Zhang

Thanks to the rapidly evolving integration of LLMs into decision-support tools, a significant transformation is happening across large-scale systems. Like other medical fields, the use of LLMs such as GPT-4 is gaining increasing interest in…

Accurate and interpretable classification of brain tumors from magnetic resonance imaging (MRI) is critical for effective diagnosis and treatment planning. This study presents an ensemble-based deep learning framework that combines…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Melika Filvantorkaman , Mohsen Piri , Maral Filvan Torkaman , Ashkan Zabihi , Hamidreza Moradi

Brain tumors represent one of the most critical neurological conditions, where early and accurate diagnosis is directly correlated with patient survival rates. Manual interpretation of Magnetic Resonance Imaging (MRI) scans is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Chinedu Emmanuel Mbonu , Tochukwu Sunday Belonwu , Okwuchukwu Ejike Chukwuogo , Kenechukwu Sylvanus Anigbogu

Complete resection of malignant gliomas is hampered by the difficulty in distinguishing tumor cells at the infiltration zone. Fluorescence guidance with 5-ALA assists in reaching this goal. Using hyperspectral imaging, previous work…

Glioma constitutes 80% of malignant primary brain tumors and is usually classified as HGG and LGG. The LGG tumors are less aggressive, with slower growth rate as compared to HGG, and are responsive to therapy. Tumor biopsy being challenging…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Subhashis Banerjee , Sushmita Mitra , Francesco Masulli , Stefano Rovetta
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