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The information bottleneck (IB) principle has been suggested as a way to analyze deep neural networks. The learning dynamics are studied by inspecting the mutual information (MI) between the hidden layers and the input and output. Notably,…

Machine Learning · Computer Science 2022-02-15 Stephan Sloth Lorenzen , Christian Igel , Mads Nielsen

Efficient communication requires balancing informativity and simplicity when encoding meanings. The Information Bottleneck (IB) framework captures this trade-off formally, predicting that natural language systems cluster near an optimal…

Computation and Language · Computer Science 2026-04-07 Antoine Taroni , Ludovic Moncla , Frederique Laforest

The rise of cost involved with drug discovery and current speed of which they are discover, underscore the need for more efficient structure-based drug design (SBDD) methods. We employ Generative Flow Networks (GFlowNets), to effectively…

Machine Learning · Computer Science 2024-06-18 Grayson Lee , Tony Shen , Martin Ester

Structure-based drug design (SBDD) leverages the 3D structure of biomolecular targets to guide the creation of new therapeutic agents. Recent advances in generative models, including diffusion models and geometric deep learning, have…

Biomolecules · Quantitative Biology 2025-01-28 Ali Khodabandeh Yalabadi , Mehdi Yazdani-Jahromi , Ozlem Ozmen Garibay

The Information Bottleneck (IB) framework is a general characterization of optimal representations obtained using a principled approach for balancing accuracy and complexity. Here we present a new framework, the Dual Information Bottleneck…

Information Theory · Computer Science 2020-06-09 Zoe Piran , Ravid Shwartz-Ziv , Naftali Tishby

Learning effective joint embedding for cross-modal data has always been a focus in the field of multimodal machine learning. We argue that during multimodal fusion, the generated multimodal embedding may be redundant, and the discriminative…

Machine Learning · Computer Science 2022-12-06 Sijie Mai , Ying Zeng , Haifeng Hu

Inference capabilities of machine learning (ML) systems skyrocketed in recent years, now playing a pivotal role in various aspect of society. The goal in statistical learning is to use data to obtain simple algorithms for predicting a…

Machine Learning · Computer Science 2020-05-04 Ziv Goldfeld , Yury Polyanskiy

We view the Information Bottleneck Principle (IBP: Tishby et al., 1999; Schwartz-Ziv and Tishby, 2017) and Predictive Information Bottleneck Principle (PIBP: Still et al., 2007; Alemi, 2019) as special cases of a family of general…

Machine Learning · Computer Science 2019-12-24 Sayandev Mukherjee

Explaining the black-box predictions of NLP models naturally and accurately is an important open problem in natural language generation. These free-text explanations are expected to contain sufficient and carefully-selected evidence to form…

Computation and Language · Computer Science 2023-07-12 Qintong Li , Zhiyong Wu , Lingpeng Kong , Wei Bi

The information bottleneck principle is an elegant and useful approach to representation learning. In this paper, we investigate the problem of representation learning in the context of reinforcement learning using the information…

Machine Learning · Computer Science 2019-11-14 Pei Yingjun , Hou Xinwen

Normalization is fundamental to deep learning, but existing approaches such as BatchNorm, LayerNorm, and RMSNorm are variance-centric by enforcing zero mean and unit variance, stabilizing training without controlling how representations…

Machine Learning · Computer Science 2026-01-30 Xiandong Zou , Jia Li , Xiaotong Yuan , Pan Zhou

Whenever communication takes place to fulfil a goal, an effective way to encode the source data to be transmitted is to use an encoding rule that allows the receiver to meet the requirements of the goal. A formal way to identify the…

Signal Processing · Electrical Eng. & Systems 2022-11-24 Francesco Pezone , Sergio Barbarossa , Paolo Di Lorenzo

The Information Bottleneck principle offers both a mechanism to explain how deep neural networks train and generalize, as well as a regularized objective with which to train models. However, multiple competing objectives are proposed in the…

Machine Learning · Computer Science 2021-01-06 Andreas Kirsch , Clare Lyle , Yarin Gal

Generating molecules with high binding affinities to target proteins (a.k.a. structure-based drug design) is a fundamental and challenging task in drug discovery. Recently, deep generative models have achieved remarkable success in…

Biomolecules · Quantitative Biology 2023-05-24 Zaixi Zhang , Qi Liu

Explaining deep learning models operating on time series data is crucial in various applications of interest which require interpretable and transparent insights from time series signals. In this work, we investigate this problem from an…

This paper investigates task-oriented communication for edge inference, where a low-end edge device transmits the extracted feature vector of a local data sample to a powerful edge server for processing. It is critical to encode the data…

Signal Processing · Electrical Eng. & Systems 2023-01-19 Jiawei Shao , Yuyi Mao , Jun Zhang

The information bottleneck (IB) method is a feasible defense solution against adversarial attacks in deep learning. However, this method suffers from the spurious correlation, which leads to the limitation of its further improvement of…

Machine Learning · Computer Science 2022-10-27 Huan Hua , Jun Yan , Xi Fang , Weiquan Huang , Huilin Yin , Wancheng Ge

The Information Bottleneck (IB) is a conceptual method for extracting the most compact, yet informative, representation of a set of variables, with respect to the target. It generalizes the notion of minimal sufficient statistics from…

Machine Learning · Computer Science 2017-11-08 Amichai Painsky , Naftali Tishby

Several generative models with elaborate training and sampling procedures have been proposed to accelerate structure-based drug design (SBDD); however, their empirical performance turns out to be suboptimal. We seek to better understand…

Machine Learning · Computer Science 2025-03-04 Rafał Karczewski , Samuel Kaski , Markus Heinonen , Vikas Garg

The information bottleneck (IB) method seeks a compressed representation of data that preserves information relevant to a target variable for prediction while discarding irrelevant information from the original data. In its classical…

Information Theory · Computer Science 2026-02-23 Akira Kamatsuka , Takahiro Yoshida