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In recent years, there have been significant advances in building end-to-end Machine Learning (ML) systems that learn at scale. But most of these systems are: (a) isolated (perception, speech, or language only); (b) trained on static…

Large Language Models (LLMs) have emerged as powerful tools for accelerating scientific discovery, yet their static knowledge and hallucination issues hinder autonomous research applications. Recent advances integrate LLMs into agentic…

Artificial Intelligence · Computer Science 2025-12-23 Zeyu Xia , Jinzhe Ma , Congjie Zheng , Shufei Zhang , Yuqiang Li , Hang Su , P. Hu , Changshui Zhang , Xingao Gong , Wanli Ouyang , Lei Bai , Dongzhan Zhou , Mao Su

Recent agent frameworks and inference-time algorithms often struggle with complex planning problems due to limitations in verifying generated plans or reasoning and varying complexity of instances within a single task. Many existing methods…

Automated model-based test generation presents a viable alternative to the costly manual test creation currently employed for regression testing of web apps. However, existing model inference techniques rely on threshold-based whole-page…

Software Engineering · Computer Science 2022-05-09 Rahulkrishna Yandrapally , Ali Mesbah

Recent advances in large language models (LLMs) have shown great potential to accelerate drug discovery. However, the specialized nature of biochemical data often necessitates costly domain-specific fine-tuning, posing major challenges.…

Machine Learning · Computer Science 2025-11-17 Namkyeong Lee , Edward De Brouwer , Ehsan Hajiramezanali , Tommaso Biancalani , Chanyoung Park , Gabriele Scalia

The aerodynamic design of turbomachinery is a complex and tightly coupled multi-stage process involving geometry generation, performance prediction, optimization, and high-fidelity physical validation. Existing intelligent design approaches…

Artificial Intelligence · Computer Science 2026-04-10 Juan Du , Yueteng Wu , Pan Zhao , Yuze Liu , Min Zhang , Xiaobin Xu , Xinglong Zhang

The automation of scientific research through large language models (LLMs) presents significant opportunities but faces critical challenges in knowledge synthesis and quality assurance. We introduce Feedback-Refined Agent Methodology…

Computation and Language · Computer Science 2025-11-18 Chengzhang Yu , Yiming Zhang , Zhixin Liu , Zenghui Ding , Yining Sun , Zhanpeng Jin

In the accelerating era of human-instructed visual content creation, diffusion models have demonstrated remarkable generative potential. Yet their deployment is constrained by a dual bottleneck: semantic ambiguity in diverse prompts and the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Jie Qin , Jie Wu , Weifeng Chen , Yueming Lyu

Modern information systems require autonomous agents capable of navigating complex workflows, yet current methodologies often struggle with the transition from structured metadata parsing to general environmental perception. While the…

Artificial Intelligence · Computer Science 2026-05-28 Susanna Cifani , Mario Luca Bernardi , Marta Cimitile

LLM-based search agents achieve strong performance but suffer from severe latency, as each step requires serialized LLM reasoning followed by action of tool execution. We revisit this bottleneck through the lens of speculation. While…

Artificial Intelligence · Computer Science 2025-11-26 Zixiao Huang , Wen Zeng , Tianyu Fu , Tengxuan Liu , Yizhou Sun , Ke Hong , Xinhao Yang , Chengchun Liu , Yan Li , Quanlu Zhang , Guohao Dai , Zhenhua Zhu , Yu Wang

The rapid advancement of large language models (LLMs) has enabled the development of multi-agent systems where multiple LLM-based agents collaborate on complex tasks. However, existing systems often rely on centralized coordination, leading…

Multiagent Systems · Computer Science 2025-06-02 Yingxuan Yang , Huacan Chai , Shuai Shao , Yuanyi Song , Siyuan Qi , Renting Rui , Weinan Zhang

While Large Language Models (LLMs) have demonstrated potential in healthcare, they often struggle with the complex, non-linear reasoning required for accurate clinical diagnosis. Existing methods typically rely on static, linear mappings…

Computation and Language · Computer Science 2026-05-28 Zhuohan Ge , Haoyang Li , Yubo Wang , Nicole Hu , Chen Jason Zhang , Qing Li

The rapid advancement of artificial intelligence, particularly autonomous agentic systems based on Large Language Models (LLMs), presents new opportunities to accelerate drug discovery by improving in-silico modeling and reducing dependence…

Large language models (LLMs) have enabled remarkable advances in automated task-solving with multi-agent systems. However, most existing LLM-based multi-agent approaches rely on predefined agents to handle simple tasks, limiting the…

Artificial Intelligence · Computer Science 2024-05-01 Guangyao Chen , Siwei Dong , Yu Shu , Ge Zhang , Jaward Sesay , Börje F. Karlsson , Jie Fu , Yemin Shi

We present SheetMind, a modular multi-agent framework powered by large language models (LLMs) for spreadsheet automation via natural language instructions. The system comprises three specialized agents: a Manager Agent that decomposes…

Human-Computer Interaction · Computer Science 2025-06-17 Ruiyan Zhu , Xi Cheng , Ke Liu , Brian Zhu , Daniel Jin , Neeraj Parihar , Zhoutian Xu , Oliver Gao

We present a modular framework powered by large language models (LLMs) that automates and streamlines key tasks across the early-stage computational drug discovery pipeline. By combining LLM reasoning with domain-specific tools, the…

Hierarchical Multi-Agent Systems provide convenient and relevant ways to analyze, model, and simulate complex systems composed of a large number of entities that interact at different levels of abstraction. In this paper, we introduce…

Machine Learning · Computer Science 2022-04-27 Ahmad Esmaeili , John C. Gallagher , John A. Springer , Eric T. Matson

Research funding discovery remains fundamentally fragmented: researchers navigate disparate agency portals (e.g., in the United States, NSF, NIH, DARPA, Grants.gov, and many others) with heterogeneous interfaces, search capabilities, and…

Artificial Intelligence · Computer Science 2026-05-05 Zhisheng Tang , Mayank Kejriwal

Effective prompt design is essential for improving the planning capabilities of large language model (LLM)-driven agents. However, existing structured prompting strategies are typically limited to single-agent, plan-only settings, and often…

Artificial Intelligence · Computer Science 2025-07-08 Bruce Yang , Xinfeng He , Huan Gao , Yifan Cao , Xiaofan Li , David Hsu

The rapid growth of scientific literature has made it increasingly difficult for researchers to efficiently discover, evaluate, and synthesize relevant work. Recent advances in multi-agent large language models (LLMs) have demonstrated…

Computation and Language · Computer Science 2026-04-08 Komal Kumar , Aman Chadha , Salman Khan , Fahad Shahbaz Khan , Hisham Cholakkal