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We consider the following basic learning task: given independent draws from an unknown distribution over a discrete support, output an approximation of the distribution that is as accurate as possible in $\ell_1$ distance (i.e. total…

Machine Learning · Computer Science 2015-11-12 Gregory Valiant , Paul Valiant

Sampling from a distribution $p(x) \propto e^{-\mathcal{E}(x)}$ known up to a normalising constant is an important and challenging problem in statistics. Recent years have seen the rise of a new family of amortised sampling algorithms,…

Machine Learning · Computer Science 2026-05-29 Arran Carter , Sanghyeok Choi , Kirill Tamogashev , Víctor Elvira , Esmeralda S. Whitammer

As neural interfaces become more advanced, there has been an increase in the volume and complexity of neural data recordings. These interfaces capture rich information about neural dynamics that call for efficient, real-time processing…

Neural and Evolutionary Computing · Computer Science 2024-08-26 Sai Deepesh Pokala , Marie Bernert , Takuya Nanami , Takashi Kohno , Timothée Lévi , Blaise Yvert

We theoretically investigate the phenomena of generalization and memorization in diffusion models. Empirical studies suggest that these phenomena are influenced by model complexity and the size of the training dataset. In our experiments,…

Machine Learning · Computer Science 2025-10-09 Anand Jerry George , Rodrigo Veiga , Nicolas Macris

Neural diffusion processes provide a scalable, non-Gaussian approach to modelling distributions over functions, but existing formulations are limited to single-task inference and do not capture dependencies across related tasks. In many…

Machine Learning · Computer Science 2026-01-19 Joseph Rawson , Domniki Ladopoulou , Petros Dellaportas

Diffusion models are widely used in applications ranging from image generation to inverse problems. However, training diffusion models typically requires clean ground-truth images, which are unavailable in many applications. We introduce…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Chicago Y. Park , Shirin Shoushtari , Hongyu An , Ulugbek S. Kamilov

Masked discrete diffusion models (MDMs) are a promising new approach to generative modelling, offering the ability for parallel token generation and therefore greater efficiency than autoregressive counterparts. However, achieving an…

Machine Learning · Computer Science 2026-03-02 David Fox , Sam Bowyer , Song Liu , Laurence Aitchison , Raul Santos-Rodriguez , Mengyue Yang

We consider the problem of sampling transition paths between two given metastable states of a molecular system, e.g. a folded and unfolded protein or products and reactants of a chemical reaction. Due to the existence of high energy…

Biomolecules · Quantitative Biology 2023-07-19 Lars Holdijk , Yuanqi Du , Ferry Hooft , Priyank Jaini , Bernd Ensing , Max Welling

Diffusion models excel at creating visually-convincing images, but they often struggle to meet subtle constraints inherent in the training data. Such constraints could be physics-based (e.g., satisfying a PDE), geometric (e.g., respecting…

Machine Learning · Computer Science 2025-04-11 Berthy T. Feng , Ricardo Baptista , Katherine L. Bouman

Stochastic differential equations (SDEs) or diffusions are continuous-valued continuous-time stochastic processes widely used in the applied and mathematical sciences. Simulating paths from these processes is usually an intractable problem,…

Computation · Statistics 2020-05-27 Qi Wang , Vinayak Rao , Yee Whye Teh

In sampling-based Bayesian models of brain function, neural activities are assumed to be samples from probability distributions that the brain uses for probabilistic computation. However, a comprehensive understanding of how mechanistic…

Neurons and Cognition · Quantitative Biology 2023-11-16 Shirui Chen , Linxing Preston Jiang , Rajesh P. N. Rao , Eric Shea-Brown

Recent years have seen deep neural networks (DNNs) becoming wider and deeper to achieve better performance in many applications of AI. Such DNNs however require huge amounts of memory to store weights and intermediate results (e.g.,…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-04-27 Taro Sekiyama , Takashi Imamichi , Haruki Imai , Rudy Raymond

For four decades statistical physics has been providing a framework to analyse neural networks. A long-standing question remained on its capacity to tackle deep learning models capturing rich feature learning effects, thus going beyond the…

Machine Learning · Statistics 2025-12-15 Jean Barbier , Francesco Camilli , Minh-Toan Nguyen , Mauro Pastore , Rudy Skerk

We introduce a novel framework for efficient sampling from complex, unnormalised target distributions by exploiting multiscale dynamics. Traditional score-based sampling methods either rely on learned approximations of the score function or…

Computation · Statistics 2025-11-04 Paula Cordero-Encinar , Andrew B. Duncan , Sebastian Reich , O. Deniz Akyildiz

The curse of dimensionality is a widely known issue in reinforcement learning (RL). In the tabular setting where the state space $\mathcal{S}$ and the action space $\mathcal{A}$ are both finite, to obtain a nearly optimal policy with…

Machine Learning · Computer Science 2022-10-28 Bingyan Wang , Yuling Yan , Jianqing Fan

Medical image annotation is constrained by privacy concerns and labor-intensive labeling, significantly limiting the performance and generalization of segmentation models. While mask-controllable diffusion models excel in synthesis, they…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Kunpeng Qiu , Zhiying Zhou , Yongxin Guo

For image generation with diffusion models (DMs), a negative prompt n can be used to complement the text prompt p, helping define properties not desired in the synthesized image. While this improves prompt adherence and image quality,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Alakh Desai , Nuno Vasconcelos

Denoising diffusion models have emerged as the go-to generative framework for solving inverse problems in imaging. A critical concern regarding these models is their performance on out-of-distribution tasks, which remains an under-explored…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Riccardo Barbano , Alexander Denker , Hyungjin Chung , Tae Hoon Roh , Simon Arridge , Peter Maass , Bangti Jin , Jong Chul Ye

Stochastic differential equations (SDEs) are an important class of time-series models, used to describe stochastic systems evolving in continuous time. Simulating paths from these processes, particularly after conditioning on noisy…

Computation · Statistics 2026-02-03 Xinyi Pei , Minhyeok Kim , Vinayak Rao

Precise control of signal propagation in modular neural networks represents a fundamental challenge in computational neuroscience. We establish a framework for identifying optimal control nodes that maximize stimulus transmission between…

Neurons and Cognition · Quantitative Biology 2025-08-18 Bulat Batuev , Arsenii Onuchin , Sergey Sukhov