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Background: Material structures at the micrometer scale cause ultra-small-angle X-ray scattering, e.g., seen in lung tissue or plastic foams. In grating-based X-ray imaging, this causes a reduction of the fringe visibility, forming a…

Dark-field radiography of the human chest has been demonstrated to have promising potential for the analysis of the lung microstructure and the diagnosis of respiratory diseases. However, previous studies of dark-field chest radiographs…

Dark-field imaging based on grating interferometry is an emerging X-ray modality in medical imaging, which is particularly capable of providing complementary diagnostic information by visualizing the microstructural properties of lung…

Medical Physics · Physics 2026-05-29 Longchao Men , Peiyuan Guo , Jincheng Lu , Yan Xu , Hongxia Yin , Zhenchang Wang , Li Zhang , Zhentian Wang

Purpose: Grating-based X-ray phase-contrast imaging is a promising modality increasing the soft tissue contrast in medical imaging. In this work, the signature of lung tissue in X-ray grating-based physe-contrast imaging is investigated.…

X-ray dark-field radiography provides complementary diagnostic information to conventional attenuation imaging by visualizing microstructural tissue changes through small-angle scattering. However, the limited availability of such data…

Machine Learning · Computer Science 2026-01-23 Lina Felsner , Henriette Bast , Tina Dorosti , Florian Schaff , Franz Pfeiffer , Daniela Pfeiffer , Julia Schnabel

Chest radiography is the most common clinical examination type. To improve the quality of patient care and to reduce workload, methods for automatic pathology classification have been developed. In this contribution we investigate the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Ivo M. Baltruschat , Leonhard Steinmeister , Harald Ittrich , Gerhard Adam , Hannes Nickisch , Axel Saalbach , Jens von Berg , Michael Grass , Tobias Knopp

In recent years, a novel x-ray imaging modality has emerged that reveals unresolved sample microstructure via a "dark-field image", which provides complementary information to conventional "bright-field" images, such as attenuation and…

The chest X-ray plays a key role in screening and diagnosis of many lung diseases including the COVID-19. More recently, many works construct deep neural networks (DNNs) for chest X-ray images to realize automated and efficient diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Binyu Tian , Qing Guo , Felix Juefei-Xu , Wen Le Chan , Yupeng Cheng , Xiaohong Li , Xiaofei Xie , Shengchao Qin

The dark-field signal uncovers details beyond conventional X-ray attenuation contrast, which is especially valuable for material sciences. In particular, dark-field techniques are able to reveal structures beyond the spatial resolution of a…

Chest X-ray is the most common test among medical imaging modalities. It is applied for detection and differentiation of, among others, lung cancer, tuberculosis, and pneumonia, the last with importance due to the COVID-19 disease.…

Image and Video Processing · Electrical Eng. & Systems 2020-03-24 Gusztáv Gaál , Balázs Maga , András Lukács

Chest radiography is an effective screening tool for diagnosing pulmonary diseases. In computer-aided diagnosis, extracting the relevant region of interest, i.e., isolating the lung region of each radiography image, can be an essential step…

Image and Video Processing · Electrical Eng. & Systems 2022-02-23 Hilda Azimi , Jianxing Zhang , Pengcheng Xi , Hala Asad , Ashkan Ebadi , Stephane Tremblay , Alexander Wong

X-ray dark-field imaging enables a spatially-resolved visualization of ultra-small-angle X-ray scattering. Using phantom measurements, we demonstrate that a material's effective dark-field signal may be reduced by modification of the…

The recent progress of computing, machine learning, and especially deep learning, for image recognition brings a meaningful effect for automatic detection of various diseases from chest X-ray images (CXRs). Here efficiency of lung…

Machine Learning · Computer Science 2018-11-21 Yu. Gordienko , Peng Gang , Jiang Hui , Wei Zeng , Yu. Kochura , O. Alienin , O. Rokovyi , S. Stirenko

This study investigates the effects of including patients' clinical information on the performance of deep learning (DL) classifiers for disease location in chest X-ray images. Although current classifiers achieve high performance using…

Image and Video Processing · Electrical Eng. & Systems 2023-12-29 Chihcheng Hsieh , Isabel Blanco Nobre , Sandra Costa Sousa , Chun Ouyang , Margot Brereton , Jacinto C. Nascimento , Joaquim Jorge , Catarina Moreira

Low-dose computed tomography (LDCT) is the current standard for lung cancer screening, yet its adoption and accessibility remain limited. Many regions lack LDCT infrastructure, and even among those screened, early-stage cancer detection…

Medical Physics · Physics 2025-11-03 Joyoni Dey , Hunter C. Meyer , Murtuza S. Taqi

Chest X-rays (X-ray images) have been proven to be effective for the diagnosis of chest diseases, including Pneumonia, Lung Opacity, and COVID-19. However, relying on traditional medical methods for diagnosis from X-ray images is prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-10-01 Omar Hesham Khater , Abdullahi Sani Shuaib , Sami Ul Haq , Abdul Jabbar Siddiqui

Dual-energy imaging is a clinically well-established technique that offers several advantages over conventional X-ray imaging. By performing measurements with two distinct X-ray spectra, differences in energy-dependent attenuation are…

Chest X-rays (CXRs) are commonly utilized as a low-dose modality for lung screening. Nonetheless, the efficacy of CXRs is somewhat impeded, given that approximately 75% of the lung area overlaps with bone, which in turn hampers the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Zhanghao Chen , Yifei Sun , Wenjian Qin , Ruiquan Ge , Cheng Pan , Wenming Deng , Zhou Liu , Wenwen Min , Ahmed Elazab , Xiang Wan , Changmiao Wang

Beam hardening (BH) is one of the major artifacts that severely reduces the quality of Computed Tomography (CT) imaging. In a polychromatic X-ray beam, since low-energy photons are more preferentially absorbed, the attenuation of the beam…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Ammar Alsaffar , Kaicong Sun , Sven Simon

In clinical CT, the x-ray source emits polychromatic x-rays, which are detected in the current-integrating mode. This physical process is accurately described by an energy-dependent non-linear integral model on the basis of the Beer-Lambert…

Medical Physics · Physics 2018-01-11 Wenxiang Cong , Ge Wang
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