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The current popular methods for video object segmentation (VOS) implement feature matching through several hand-crafted modules that separately perform feature extraction and matching. However, the above hand-crafted designs empirically…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Qiangqiang Wu , Tianyu Yang , Wei WU , Antoni Chan

The potential of virtual reality (VR) to contribute to drug design and development has been recognised for many years. Hardware and software developments now mean that this potential is beginning to be realised, and VR methods are being…

Biomolecules · Quantitative Biology 2022-02-09 Rebecca K. Walters , Ella M. Gale , Jonathan Barnoud , David R. Glowacki , Adrian J. Mulholland

We present DeepSeek-VL, an open-source Vision-Language (VL) Model designed for real-world vision and language understanding applications. Our approach is structured around three key dimensions: We strive to ensure our data is diverse,…

Artificial Intelligence · Computer Science 2024-03-12 Haoyu Lu , Wen Liu , Bo Zhang , Bingxuan Wang , Kai Dong , Bo Liu , Jingxiang Sun , Tongzheng Ren , Zhuoshu Li , Hao Yang , Yaofeng Sun , Chengqi Deng , Hanwei Xu , Zhenda Xie , Chong Ruan

Computer-aided drug discovery is an essential component of modern drug development. Therein, deep learning has become an important tool for rapid screening of billions of molecules in silico for potential hits containing desired chemical…

This paper introduces a novel Hybrid Visual Servoing (HVS) approach for controlling tendon-driven continuum robots (TDCRs). The HVS system combines Image-Based Visual Servoing (IBVS) with Deep Learning-Based Visual Servoing (DLBVS) to…

Robotics · Computer Science 2025-02-21 Rana Danesh , Farrokh Janabi-Sharifi , Farhad Aghili

Writing programs for heterogeneous platforms optimized for high performance is hard since this requires the code to be tuned at a low level with architecture-specific optimizations that are most times based on fundamentally differing…

Computer Vision and Pattern Recognition · Computer Science 2020-08-31 M. Akif Özkan , Burak Ok , Bo Qiao , Jürgen Teich , Frank Hannig

Accurate prediction of protein-ligand binding affinities is an essential challenge in structure-based drug design. Despite recent advances in data-driven methods for affinity prediction, their accuracy is still limited, partially because…

Biomolecules · Quantitative Biology 2024-09-04 Yaosen Min , Ye Wei , Peizhuo Wang , Xiaoting Wang , Han Li , Nian Wu , Stefan Bauer , Shuxin Zheng , Yu Shi , Yingheng Wang , Ji Wu , Dan Zhao , Jianyang Zeng

Cancer is the second leading cause of death, with chemotherapy as one of the primary forms of treatment. As a result, researchers are turning to drug combination therapy to decrease drug resistance and increase efficacy. Current methods of…

Quantitative Methods · Quantitative Biology 2024-11-08 Zachary Schwehr

We present a novel cross-view classification algorithm where the gallery and probe data come from different views. A popular approach to tackle this problem is the multi-view subspace learning (MvSL) that aims to learn a latent subspace…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Jiamiao Xu , Shujian Yu , Xinge You , Mengjun Leng , Xiao-Yuan Jing , C. L. Philip Chen

Virtual screening (VS) is widely used during computational drug discovery to reduce costs. Chemogenomics-based virtual screening (CGBVS) can be used to predict new compound-protein interactions (CPIs) from known CPI network data using…

Quantitative Methods · Quantitative Biology 2021-05-04 Masahito Ohue , Takuro Yamazaki , Tomohiro Ban , Yutaka Akiyama

Video super-resolution (VSR) is a prominent research topic in low-level computer vision, where deep learning technologies have played a significant role. The rapid progress in deep learning and its applications in VSR has led to a…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Arbind Agrahari Baniya , Tsz-Kwan Lee , Peter Eklund , Sunil Aryal

We propose an online multi-view depth prediction approach on posed video streams, where the scene geometry information computed in the previous time steps is propagated to the current time step in an efficient and geometrically plausible…

Computer Vision and Pattern Recognition · Computer Science 2021-07-23 Arda Düzçeker , Silvano Galliani , Christoph Vogel , Pablo Speciale , Mihai Dusmanu , Marc Pollefeys

Vector set search, an underexplored similarity search paradigm, aims to find vector sets similar to a query set. This search paradigm leverages the inherent structural alignment between sets and real-world entities to model more…

Databases · Computer Science 2025-07-08 Yiqi Li , Sheng Wang , Zhiyu Chen , Shangfeng Chen , Zhiyong Peng

In contemporary pathology, multiplexed immunofluorescence (mIF) and multiplex immunohistochemistry (mIHC) present both significant opportunities and challenges. These methodologies shed light on intricate tumor microenvironment…

High-dimensional vector similarity search (HVSS) is gaining prominence as a powerful tool for various data science and AI applications. As vector data scales up, in-memory indexes pose a significant challenge due to the substantial increase…

High throughput screening of compounds (chemicals) is an essential part of drug discovery [7], involving thousands to millions of compounds, with the purpose of identifying candidate hits. Most statistical tools, including the industry…

Machine Learning · Statistics 2017-09-29 Ivo D. Shterev , David B. Dunson , Cliburn Chan , Gregory D. Sempowski

Deep learning models have driven significant progress in predicting protein function and interactions at the protein level. While these advancements have been invaluable for many biological applications such as enzyme engineering and…

Machine Learning · Computer Science 2025-05-20 Yang Tan , Wenrui Gou , Bozitao Zhong , Liang Hong , Huiqun Yu , Bingxin Zhou

Text recognition is an inherent integration of vision and language, encompassing the visual texture in stroke patterns and the semantic context among the character sequences. Towards advanced text recognition, there are three key…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Humen Zhong , Zhibo Yang , Zhaohai Li , Peng Wang , Jun Tang , Wenqing Cheng , Cong Yao

Finding new drugs is getting harder and harder. One of the hopes of drug discovery is to use machine learning models to predict molecular properties. That is why models for molecular property prediction are being developed and tested on…

Machine Learning · Computer Science 2023-10-11 Simon Steshin

Due to their excellent drug-like and pharmacokinetic properties, small molecule drugs are widely used to treat various diseases, making them a critical component of drug discovery. In recent years, with the rapid development of deep…

Machine Learning · Computer Science 2025-05-15 Kun Li , Yida Xiong , Hongzhi Zhang , Xiantao Cai , Jia Wu , Bo Du , Wenbin Hu